Results 41 to 50 of about 7,015 (221)
Red-Shifted Aequorin Variants Incorporating Non-Canonical Amino Acids: Applications in In Vivo Imaging. [PDF]
PLoS ONE, 2016 The increased importance of in vivo diagnostics has posed new demands for imaging technologies. In that regard, there is a need for imaging molecules capable of expanding the applications of current state-of-the-art imaging in vivo diagnostics.
Kristen M Grinstead +7 more
doaj +1 more source
Luciferin production and luciferase transcription in the bioluminescent copepod Metridia lucens [PDF]
PeerJ, 2018 Bioluminescent copepods are often the most abundant marine zooplankton and play critical roles in oceanic food webs. Metridia copepods exhibit particularly bright bioluminescence, and the molecular basis of their light production has just recently begun ...
Michael Tessler +7 more
doaj +2 more sources
BBA Advances, 2023 Gaussia luciferase (GLuc 18.2kDa; 168 residues) is a marine copepod luciferase that emits a bright blue light when oxidizing coelenterazine (CTZ). It is a helical protein where two homologous sequential repeats form two anti-parallel bundles, each made ...
Kyoko Takatsu +5 more
doaj +1 more source
bioRxiv, 2022 Gaussia luciferase (GLuc 18.2kDa; 168 residues) is a marine copepod luciferase that emits a bright blue light when oxidizing coelenterazine (CTZ). It is a helical protein where two homologous sequential repeats form two anti-parallel bundles, each made ...
Kyoko Takatsu +5 more
semanticscholar +1 more source
Bioluminescence in an Undescribed Species of Carnivorous Sponge (Cladorhizidae) From the Deep Sea
Frontiers in Marine Science, 2020 One dominant ecological trait in the dimly-lit deep-sea is the ability of organisms to emit bioluminescence. Despite its many ecological roles in deep-sea ecosystems, the presence of inherent bioluminescence in marine sponges has been debated for more ...
Séverine Martini +5 more
doaj +1 more source
Chemiluminescence Imaging of Superoxide Anion Detects Beta-Cell Function and Mass. [PDF]
PLoS ONE, 2016 Superoxide anion is produced during normal cellular respiration and plays key roles in cellular physiology with its dysregulation being associated with a variety of diseases.
Laura L Bronsart +2 more
doaj +1 more source
Molecules, 2022 Marine Coelenterazine is one of the most well-known chemi-/bioluminescent systems, and in which reaction the chemi-/bioluminophore (Coelenteramide) is generated and chemiexcited to singlet excited states (leading to light emission).
Ana Carolina P. Afonso +3 more
doaj +1 more source
Coelenterazine Derivatives as Potential Drugs for Photodynamic Therapy
Medical Sciences Forum, 2022 Cancer is one of the main leading causes of death worldwide, and its treatment is highly complex and known to cause serious side effects for patients.
Daiane Nascimento Maronde +4 more
doaj +1 more source
Core‐Modified Coelenterazine Luciferin Analogues: Synthesis and Chemiluminescence Properties [PDF]
Chemistry – A European Journal, 2020 AbstractIn this work on the design and studies of luciferins related to the blue‐hued coelenterazine, the synthesis of heterocyclic analogues susceptible to produce a photon, possibly at a different wavelength, is undertaken. Here, the synthesis of O‐acetylated derivatives of imidazo[1,2‐b]pyridazin‐3(5 H)‐one, imidazo[2,1‐f][1,2,4]triazin‐7(1 H)‐one ...
Glwadys Gagnot +8 more
openaire +3 more sources
PLoS Comput. Biol.Gaussia Luciferase (GLuc) is a renowned reporter protein that can catalyze the oxidation of coelenterazine (CTZ) and emit a bright light signal. GLuc comprises two consecutive repeats that form the enzyme body and a central putative catalytic cavity ...
Nan Wu +6 more
semanticscholar +1 more source