Results 61 to 70 of about 6,471 (200)
British Journal of Pharmacology, Volume 183, Issue 18, Page 5641-5656, September 2026.Abstract Background and Purpose Apelin and Elabela are endogenous ligands of the apelin receptor (apelin receptor/APJ), a GPCR involved in cardiovascular regulation and body fluid homeostasis. The human receptor contains a conserved disulfide bridge linking the N‐terminal domain to extracellular loop 3 (ECL3) via Cys19 and Cys281, forming a structural ...
Chloé Bonef +11 more
wiley +1 more source
The intrinsic fluorescence of apo-obelin and apo-aequorin and use of its quenching to characterize coelenterazine binding. [PDF]
, 2009 The intrinsic fluorescence of two apo-photoproteins has been characterized and its concentration-dependent quenching by coelenterazine has been for the first time applied to determine the apparent dissociation constants for coelenterazine binding with ...
Markova, S.V. +18 more
core +1 more source
, 2022 Luminescence activities of reverse mutants of nanoKAZ using coelenterazine (CTZ) and CTZ analogs as a substrate.
Mikako Shirouzu (272392) +7 more
core +1 more source
Evaluation of the anticancer activity and chemiluminescence of a halogenated coelenterazine analog [PDF]
, 2023 Chemiluminescence is a remarkable process in which light is emitted due to a chemical reaction, without the need for photoexcitation. Among some of the most well-known chemiluminescent systems is that of marine Coelenterazine.
José Pedro Silva +7 more
core +1 more source
A tomato MIK2‐clade receptor is involved in the perception of a Fusarium‐derived elicitor
New Phytologist, Volume 251, Issue 5, Page 2777-2798, September 2026.Fusarium elicitor responsivness and MIK2‐clade proteins are conserved across plant families. Summary Plants continuously monitor their environment to adapt to threats affecting health and fitness. Cell‐surface receptors detect conserved microbe‐associated molecular patterns (MAMPs) or endogenous immunogenic signals to activate signaling pathways that ...
Julian Maroschek +6 more
wiley +1 more source
ChemMedChem, Volume 21, Issue 16, 27 August 2026.Four series of 20 (het)aryl substituted 7‐deazapurine nucleobases were synthesized. Several potent antagonists of all four subtypes of adenosine receptors were identified by functional assay. High‐throughput screening of the IMTM compound library for modulatory activity on adenosine receptors (ARs) identified two deazapurine hits based on 2,6‐diaryl‐7 ...
Ugnė Šinkevičiūtė +9 more
wiley +1 more source
British Journal of Pharmacology, Volume 183, Issue 16, Page 4715-4734, August 2026.Abstract Background and Purpose New synthetic cannabinoid receptor agonists (SCRAs) are associated with severe adverse effects, including unexpected psychiatric symptoms. These compounds are mainly active through their potent agonism on the cannabinoid receptors CB1 and CB2.
Giorgia Corli +8 more
wiley +1 more source
Es werde Licht! Licht als Antrieb und Regulator in synthetischen Zellen
Angewandte Chemie, Volume 138, Issue 24, 8 June 2026.Zellen sind Systeme außerhalb des Gleichgewichts, die ihre Eigenschaften in Raum und Zeit regulieren. In biomimetischen synthetischen Zellen bietet Licht eine einzigartige Möglichkeit, Vorgänge räumlich und zeitlich anzutreiben und zu kontrollieren.
Matthew E. Allen +5 more
wiley +1 more source
, 2022 Inhibition of luminescence activity of CTZ-utilizing luciferases with deaza-coelenterazine (daCTZ) analogs as inhibitors.
Mikako Shirouzu (272392) +7 more
core +1 more source
Bioluminescent Mammalian Cells Grown in Sponge Matrices to Monitor Immune Rejection
Molecular Imaging, 2007 The growth and bioluminescence of cells seeded in collagen and gelatin sponge matrices were compared in vitro under different conditions, and immune rejection was quantified and visualized directly in situ based on loss of bioluminescence activity ...
Okechukwu Ojogho +3 more
doaj +1 more source