Results 51 to 60 of about 6,471 (200)
New Phytologist, EarlyView.Model of the cell wall damage (CWD)‐responsive signaling network leading to camalexin biosynthesis. Summary Plant cell walls constitute dynamic barriers that are essential for defense against pathogens. Beyond a structural role in blocking pathogen infection, innate mechanisms monitor cell wall integrity (CWI) in Arabidopsis thaliana and trigger local ...
Richard Noi Morton +9 more
wiley +1 more source
Presence of coelenterazine in mesopelagic fishes from the Strait of Messina
, 1995 Coelenterazine, a luciferine, and luciferase activity specific to coelenterazine were detected and assayed in various tissues of mid-water fishes, Argyropelecus hemigymnus, Chauliodus sloani, Myctophum punctatum, Vinciguerria attenuata and Cyclothone ...
Mallefet, Jérôme, Shimomura, O
core +1 more source
Bioluminescent imaging of Trypanosoma brucei shows preferential testis dissemination which may hamper drug efficacy in sleeping sickness. [PDF]
PLoS Neglected Tropical Diseases, 2009 Monitoring Trypanosoma spread using real-time imaging in vivo provides a fast method to evaluate parasite distribution especially in immunoprivileged locations.
Filip Claes +8 more
doaj +1 more source
Mechanisms of XCR1 Membrane Trafficking and Constitutive Endocytosis
Basic &Clinical Pharmacology &Toxicology, Volume 139, Issue 5, November 2026.ABSTRACT Chemokines orchestrate immune cell trafficking through receptor‐mediated signalling and are implicated in inflammatory, autoimmune and neuropathic disorders. The XCL1–XCR1 axis is of particular interest because XCR1 is selectively expressed on mature conventional type 1 dendritic cells (cDC1s), where it supports communication with activated ...
Qiao Li +3 more
wiley +1 more source
, 1995 Coelenterazine chemiluminescence is now established as the most common chemistry responsible for bioluminescence in the sea, being found in seven phyla. However, the organisms which synthesize coelenterazine have yet to be identified.
Herring, P. J. +2 more
core +1 more source
British Journal of Pharmacology, Volume 183, Issue 19, Page 5871-5894, October 2026.A pharmacological profiling of 58 synthetic stimulants of various classes at dopamine, norepinephrine, and serotonin transporters and the 5‐HT2A receptor, most showing distinct class‐dependent profiles, with some indicating a high abuse potential. Background and Purpose New psychoactive substances (NPSs) often emerge on the illicit drug market with ...
Darta Stalberga +9 more
wiley +1 more source
In Vivo Testing of Luciferase Substrate Analogs in an Orthotopic Murine Model of Human Glioblastoma
Molecular Imaging, 2006 In vivo bioluminescent imaging using cells expressing Renilla luciferase is becoming increasingly common. Hindrances to the more widespread use of Renilla luciferase are the high autoluminescence of its natural substrate, coelenterazine, in plasma; the ...
Maya Otto-Duessel +5 more
doaj +1 more source
Coelenterazine detection in five myctophid species from the Kerguelen Plateau
, 2019 Myctophidae comprise the largest biomass of mesopelagic fishes in the Southern Ocean. This family has the ability to emit light – bioluminescence – via specific organs called photophores, and from the head and caudal organs. Through biochemical analyses,
Hermans, Claire +6 more
core +3 more sources
British Journal of Pharmacology, Volume 183, Issue 17, Page 5315-5335, September 2026.Abstract Background and Purpose β2‐adrenoceptor (β2AR) agonists are the cornerstone of asthma therapy and promote bronchodilation through Gαs signalling in airway smooth muscle (ASM), but their efficacy is limited by β‐arrestin‐mediated β2AR desensitization.
Sushrut D. Shah +7 more
wiley +1 more source
Scientific Reports, 2022 Coelenterazine-v (CTZ-v), a synthetic vinylene-bridged π-extended derivative, is able to significantly alter bioluminescence spectra of different CTZ-dependent luciferases and photoproteins by shifting them towards longer wavelengths.
Pavel V. Natashin +11 more
doaj +1 more source