Results 111 to 120 of about 136,670 (296)
KINASES FOR THE SYNTHESIS OF COENZYME A AND TRIPHOSPHOPYRIDINE NUCLEOTIDE
T.P. Wang, Nathan O. Kaplan
openalex +1 more source
Abstract Background and aims The heart is a metabolic organ rich in mitochondria. The failing heart reprograms to utilize different energy substrates, which increase its oxygen consumption. These adaptive changes contribute to increased oxidative stress.
Qinghong Li+12 more
wiley +1 more source
THE CATALYTIC FUNCTION OF COENZYME A IN CITRIC ACID SYNTHESIS
G. David Novelli, Fritz Lipmann
openalex +1 more source
Improving clinical translation of mitoprotective therapies. 31P MRI, phosphorus‐31 magnetic resonance imaging; hiPSC‐CM, human‐induced pluripotent stem cell‐derived cardiomyocyte; IHD, ischaemic heart disease. Abstract Acute myocardial infarction (MI) remains a major cause of death and disability worldwide.
Melanie Paillard+29 more
wiley +1 more source
The Biosynthesis of β-Hydroxy-β-methylglutaryl Coenzyme A in Yeast
James J. Ferguson, Harry Rudney
openalex +1 more source
Abstract A better understanding of additional mechanisms of heart failure (HF) progression may allow a different and more complete phenotyping of the disease and identification of novel therapeutic targets. Persistent latent myocardial inflammation/immune activation in HF may represent an attempt to restore tissue homeostasis in the failing heart ...
Gabriele Fragasso+20 more
wiley +1 more source
Computational modelling of myocardial metabolism in patients with advanced heart failure
LV, left ventricular; LVAD, left ventricular assist device; LVEF, left ventricular ejection fraction. Abstract Aims Perturbations of myocardial metabolism and energy depletion are well‐established hallmarks of heart failure (HF), yet methods for their systematic assessment remain limited in humans.
Niklas Beyhoff+17 more
wiley +1 more source
ENZYMATIC SYNTHESIS OF THE COENZYME A DERIVATIVES OF LONG CHAIN FATTY ACIDS
Arthur Kornberg, W.E. Pricer
openalex +1 more source
Abstract Although inborn errors of metabolism (IEM) are a rare cause of epilepsy, seizures are a common presentation in these disorders. Seizures in IEM are frequently refractory to conventional anti‐seizure medication and might warrant initiation of specific treatments based on vitamins or dietary modifications or provision of alternative substrates ...
D. Kapoor+7 more
wiley +1 more source