Results 111 to 120 of about 25,277,741 (360)

Evaluation of The Analgesic Activity of Coenzyme Q10 Ointment in Mice

Journal of Applied Veterinary Sciences, 2020
The aim of this study is to examine analgesic effect of Coenzyme Q10 ointment in mice. Fifteen healthy male albino mice were selected for this study. The animals were divided into three groups of five animals for each group.
Ibtisam T. Al-Jureisy, Wael T. Al-Wattar, Ghada A. Taqa   +2 more
doaj   +1 more source

Essential role of coenzyme A in pyruvate dehydrogenase kinase activity [PDF]

, 1982
The rate of phosphorylation and concomitant inactivation of purified pig heart muscle pyruvate dehydrogenase complex by intrinsic kinase (EC 2.7.1.99) is markedly accelerated by the addition of coenzyme A to the incubation medium, showing a half-maximum ...
Siess, E.A., Weiland, O.H.
core   +1 more source

Polymer Brush‐Based Asymmetric Porous Patch with Excellent Anti‐Bacterial and Anti‐Contamination Properties Enables Infectious Abdominal Wall Defect Repair

Advanced Science, EarlyView.
A zwitterionic asymmetric patch is developed via self‐induced phase separation. The cationic layer exhibits anti‐bacterial efficacy and releases pro‐healing factor, while the zwitterionic hydrogel prevents contamination and visceral adhesion. The strong mechanical interlocking of two layers leads to a high and stable burst pressure tolerance.
Zeping Huang, Weiwen Liang, Binying Peng, Yang Ouyang, Zixin Chen, Mawsoom Mamut, Zhipeng Huang, Hui Wang, Rongkang Huang, Bo Ma, Bingna Zheng, Jian Cai   +11 more
wiley   +1 more source

Associations between Coenzyme Q10 Status, Oxidative Stress, and Muscle Strength and Endurance in Patients with Osteoarthritis

Antioxidants, 2020
Osteoarthritis (OA) causes oxidative stress. Coenzyme Q10 is an antioxidant that participates in energy production in the human body. The purpose of this study was to investigate the relationships among coenzyme Q10 status, oxidative stress, antioxidant ...
Po-Sheng Chang, Chi-Hua Yen, Yu-Yun Huang, Ching-Ju Chiu, Ping-Ting Lin   +4 more
doaj   +1 more source

Exogenous coenzyme Q10 modulates MMP-2 activity in MCF-7 cell line as a breast cancer cellular model [PDF]

, 2010
Background/Aims Matrix Metalloproteinases 2 is a key molecule in cellular invasion and metastasis. Mitochondrial ROS has been established as a mediator of MMP activity. Coenzyme Q10 contributes to intracellular ROS regulation.
A Adhikary, A Ortega, AR Rosenkranz, C Schmelzer, CJ Cheng, GP Littarru, Hossein Mirmiranpour, HP Chao, IV Voronkina, J Wenk, JS Lazo, K Kessenbrock, K Kupai, KK Nelson, L Rusciani, Maliheh Paknejad, Massih Bahar, Mohammad Reza Khorramizadeh, MR Khorramizadeh, N Abbasi, N Hertz, NS Brown, O Portakal, OW Griffith, P Bogani, P Bogani, P Brenneisen, P Pei, P Sachdanandam, P Shekelle, Parvin Pasalar, Q Qian, R Ala-aho, R Roy, S Das, S Das, S Yuvaraj, SC Tyagi, Shahnaz Khaghani, Siavash Gerayesh Nejad, T Ito, T Sandhya, VG Premkumar, VG Premkumar, VM Factor, VM Factor, WS Wu   +46 more
core   +3 more sources

Cardiac Slc25a49‐Mediated Energy Reprogramming Governs Doxorubicin‐Induced Cardiomyopathy through the G6P–AP‐1–Sln Axis

Advanced Science, EarlyView.
Doxorubicin‐induced cardiomyopathy involves mitochondrial energy metabolism dysfunction, exacerbated by cardiomyocyte‐specific Slc25a49 deficiency via oxidative phosphorylation (OXPHOS) suppression and glycolysis activation. The Slc25a49–glucose‐6‐phosphate (G6P)–activator protein‐1 (AP‐1) axis drives myocardial injury by upregulating Sln, disrupting ...
Sitong Wan, Jingyi Qi, Yi Xia, Chang Fan, Teng Xu, Xu Zhang, Jiaxin Shi, Chenxuan Wang, Yitong Cheng, Dongyuan Zhang, Rong Liu, Yinhua Zhu, Changchang Cao, Dekui Jin, Peng An, Yongting Luo, Junjie Luo   +16 more
wiley   +1 more source

Disorders of Human Coenzyme Q10 Metabolism: An Overview

International Journal of Molecular Sciences, 2020
Coenzyme Q10 (CoQ10) has a number of vital functions in all cells, both mitochondrial and extramitochondrial. In addition to its key role in mitochondrial oxidative phosphorylation, CoQ10 serves as a lipid soluble antioxidant, plays an important role in ...
I. Hargreaves, R. Heaton, D. Mantle
semanticscholar   +1 more source

Revised nomenclature for the mammalian long-chain acyl-CoA synthetase gene family

Journal of Lipid Research, 2004
By consensus, the acyl-CoA synthetase (ACS) community, with the advice of the human and mouse genome nomenclature committees, has revised the nomenclature for the mammalian long-chain acyl-CoA synthetases.
Douglas G. Mashek, Karin E. Bornfeldt, Rosalind A. Coleman, Johannes Berger, David A. Bernlohr, Paul Black, Concetta C. DiRusso, Steven A. Farber, Wen Guo, Naohiro Hashimoto, Varsha Khodiyar, Frans A. Kuypers, Lois J. Maltais, Daniel W. Nebert, Alessandra Renieri, Jean E. Schaffer, Andreas Stahl, Paul A. Watkins, Vasilis Vasiliou, Tokuo T. Yamamoto   +19 more
doaj  

Overcoming Extreme Ammonia Inhibition on Methanogenesis by Artificially Constructing a Synergistically Community with Acidogenic Bacteria and Hydrogenotrophic Archaea

Advanced Science, EarlyView.
This study proposes a two‐step biological strategy to synergistically enhance the three stages of anaerobic digestion, ultimately eliminating the extreme ammonia inhibition and breaking through the inefficiency bottleneck of conventional biotechnology.
Heng Wu, Huaiwen Zhang, Taili Dong, Zhenyu Li, Xiaohui Guo, Heyu Chen, Yiqing Yao   +6 more
wiley   +1 more source

Functional consequences of brain exposure to saturated fatty acids: From energy metabolism and insulin resistance to neuronal damage

Endocrinology, Diabetes &Metabolism, Volume 6, Issue 1, January 2023., 2023
Saturated fatty acids induce insulin resistance in neurons. Neuronal metabolism of palmitic acid alters mitochondrial function. Abstract Introduction Saturated fatty acids (FAs) are the main component of high‐fat diets (HFDs), and high consumption has been associated with the development of insulin resistance, endoplasmic reticulum stress and ...
Karina Sánchez‐Alegría, Clorinda Arias   +1 more
wiley   +1 more source