Results 121 to 130 of about 2,692,536 (314)

Biallelic pathogenic variants in COX11 are associated with an infantile‐onset mitochondrial encephalopathy

open access: yesHuman Mutation, Volume 43, Issue 12, Page 1970-1978, December 2022., 2022
Abstract Primary mitochondrial diseases are a group of genetically and clinically heterogeneous disorders resulting from oxidative phosphorylation (OXPHOS) defects. COX11 encodes a copper chaperone that participates in the assembly of complex IV and has not been previously linked to human disease. In a previous study, we identified that COX11 knockdown
Rocio Rius   +15 more
wiley   +1 more source

Role of mitochondria in neuronal cell death induced by oxidative stress; neuroprotection by Coenzyme Q10

open access: yesNeurobiology of Disease, 2005
Neuronal cells depend on mitochondrial oxidative phosphorylation for most of their energy needs and therefore are at a particular risk for oxidative stress.
M. Somayajulu   +5 more
doaj  

Development of an Organoautocatalyzed Double σ‐Bond C(sp2)‐N Transamination Metathesis Reaction

open access: yesAngewandte Chemie International Edition, Accepted Article.
The transamination reaction, which involves the conversion of one amine to another, traditionally relies on biological enzyme catalysts. Although chemists have recently developed a few transition metal‐catalyzed methods, mimicking these enzymes to interconvert amine groups in acyclic substrates via transamination metathesis of a single C(sp2)–N bond ...
Volker Klein   +7 more
wiley   +1 more source

BIOSYNTHESIS OF FLAVIN COENZYMES BY MICROORGANISMS

open access: bronze, 1959
Hideo Katagiri   +2 more
openalex   +2 more sources

A Method for the Purification of Coenzyme a from Yeast

open access: hybrid, 1953
Helmut Beinert   +6 more
openalex   +1 more source

Metabolomic analysis reveals the molecular mechanism related to leg abnormality in broilers

open access: yesAnimal Research and One Health, EarlyView.
The graphical abstract shows the principal results of this study. Compared to the leg normal broilers, the serum calcium to phosphorus ratio was extremely decreased in the group with deformed leg bones. Additionally, a total of nine differential metabolites significantly associated with leg abnormalities and serum calcium and phosphorus levels were ...
Jumei Zheng   +9 more
wiley   +1 more source

Inactivation of human liver bile acid CoA:amino acid N-acyltransferase by the electrophilic lipid, 4-hydroxynonenal

open access: yesJournal of Lipid Research, 2008
The hepatic enzyme bile acid CoA:amino acid N-acyltransferase (BAT) catalyzes the formation of amino acid-conjugated bile acids. In the present study, protein carbonylation of BAT, consistent with modification by reactive oxygen species and their ...
E.M. Shonsey   +6 more
doaj  

Characterization of the pattern of development of key compounds contributing to aroma quality of chicken meat and their metabolic markers

open access: yesAnimal Research and One Health, EarlyView.
The graphical abstract shows the principal results of this study. Eight major aroma‐contributing compounds (nonanal, octanal, dimethyl tetrasulfide, hexanal, 1‐octen‐3‐ol, (E)‐2‐nonenal, heptanal, and (E,E)‐2,4‐decadienal) were identified by electronic nose and GC‐O‐MS analysis, and their content increased with age.
Yanke Wang   +6 more
wiley   +1 more source

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