The concentration of coenzyme-like substance in blood following the administration of nicotinic acid to normal individuals and pellagrins [PDF]
, 1938 Henry I. Kohn
openalex +1 more source
Advanced Science, EarlyView.Biosynthesis rates of 13 FFAs are quantitatively calculated in 15 tissues from glucose and an analytical framework to quantitatively calculate inter‐tissue communications of fatty acids between the liver and other tissues is developed. Moreover, the approach is extended to aging condition and a system‐wide decline of fatty acid synthesis in peripheral ...
Beizi Xing +4 more
wiley +1 more source
Angewandte Chemie, EarlyView.Lsd18 is a flavin‐dependent monooxygenase from Streptomyces lasalocidi that performs two enantioselective epoxidations during lasalocid A biosynthesis. X‐ray crystal structures of Lsd18 bound to a substrate and product analogue illuminate how this enzyme performs multiple epoxidations on the same substrate molecule and how it controls stereoselectivity.
Qian Wang +12 more
wiley +2 more sources
Antioxidantes dietéticos para la prevención de la periodontitis crónica y su tratamiento. Una revisión de las evidencias actuales procedentes de estudios en animales y humanos [PDF]
, 2015 Objetivos. Dada la relación existente entre periodontitis crónica y altos niveles de estrés oxidativo, esta revisión pretende clarificar qué papel puede desempeñar la ingesta de los diferentes antioxidantes de la dieta en el mantenimiento de un ...
Bullon, Pedro
core
Advanced Science, EarlyView.γGC deficiency in ulcerative colitis drives macrophage ferroptosis‐mediated inflammation. Claw‐engaged microparticles armed with γGC (γGC‐MPs) enhance lesion targeting, promoting localized γGC release and tissue uptake. On the cover, Monkey King (Macrophages) was bound by the Immortal‐Binding Rope and subsequently sealed beneath the Five‐Fingered ...
Rong Wang +10 more
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Development of an Organoautocatalyzed Double σ‐Bond C(sp2)‐N Transamination Metathesis Reaction
Angewandte Chemie, EarlyView.Organoautocatalyzed transamination metathesis of cyclic tertiary amines is disclosed as a high‐yielding, scalable reaction that proceeds under mild, catalyst‐free conditions. It operates via a multi‐step domino reaction mechanism, where an in situ‐formed pyrrolidinium salt functions as a HBD organoautocatalyst.
Volker Klein +7 more
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Efficacy of coenzyme Q10 in patients with cardiac failure: a meta-analysis of clinical trials
BMC Cardiovascular Disorders, 2017 Background The therapeutic efficacy of coenzyme Q10 on patients with cardiac failure remains controversial. We pooled previous clinical studies to re-evaluate the efficacy of coenzyme Q10 in patients with cardiac failure.
Li Lei, Yan Liu
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Refinements of the inequalities between Neuman-Sandor, arithmetic, contra-harmonic and quadratic means [PDF]
arXiv, 2012 In this paper, we prove that the inequalities $\alpha [1/3 Q(a,b)+2/3 A(a,b)]+(1-\alpha)Q^{1/3}(a,b)A^{2/3}(a,b)
arxiv
Mitochondrial dysfunction promoted by Porphyromonas gingivalis lipopolysaccharide as a possible link between cardiovascular disease and periodontitis [PDF]
, 2011 Oxidative stress is one of the factors that could explain the pathophysiological mechanism of inflammatory conditions that occur in cardiovascular disease (CVD) and periodontitis.
Battino, Maurizio +5 more
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A Feedback Loop Between Fatty Acid Metabolism and Epigenetics in Clear Cell Renal Carcinoma
Advanced Science, EarlyView.The current study has profiled the landscape of active enhancers in ccRCC and identified FABP5 as an oncogene. FABP5 is essential for the lipid droplet formation driven by HIFs and critical for H3K27ac and enhancer activity. The study has discovered the function of a feedback loop between epigenetics and lipid metabolism regulated by FABP5 in ccRCC ...
Zhou Ye +21 more
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