Results 41 to 50 of about 231,600 (190)
Coenzyme A corrects pathological defects in human neurons of PANK2‐associated neurodegeneration
EMBO Molecular Medicine, 2016 Pantothenate kinase‐associated neurodegeneration (PKAN) is an early onset and severely disabling neurodegenerative disease for which no therapy is available.
Daniel I Orellana +15 more
doaj +1 more source
Oleic acid is a potent inhibitor of fatty acid and cholesterol synthesis in C6 glioma cells
Journal of Lipid Research, 2007 Glial cells play a pivotal role in brain fatty acid metabolism and membrane biogenesis. However, the potential regulation of lipogenesis and cholesterologenesis by fatty acids in glial cells has been barely investigated.
Francesco Natali +3 more
doaj +1 more source
A Case of Statin-Associated Autoimmune Myopathy. [PDF]
, 2017 A 70-year-old previously independent man developed progressive proximal leg weakness resulting in a fall at home suffering traumatic brain injury. He was prescribed a statin medication two years prior, but this was discontinued on admission to the ...
Dokukin, Andrei N +6 more
core +3 more sources
A cross-metathesis approach to novel pantothenamide derivatives
Beilstein Journal of Organic Chemistry, 2016 Pantothenamides are known for their in vitro antimicrobial activity. Our group has previously reported a new stereoselective route to access derivatives modified at the geminal dimethyl moiety.
Jinming Guan +5 more
doaj +1 more source
Frontiers in Physiology, 2017 Coenzyme Q is a lipid that participates to important physiological functions. Coenzyme Q is synthesized in multiple steps from the precursor 4-hydroxybenzoic acid.
Fabien Pierrel
doaj +1 more source
Coenzyme Q10 ameliorates BPA-induced apoptosis by regulating autophagy-related lysosomal pathways
Ecotoxicology and Environmental Safety, 2021 Bisphenol A (BPA) is a widely distributed environmental endocrine disruptor. The accumulation of BPA has been proved that produce various toxic effects both on human and animals. However, the strategies to reduce the damage of BPA on the body and related
Yuan Liu +7 more
doaj +1 more source
Effect of Dietary Coenzyme Q10 on Cholesterol Metabolism in Growing Chickens
The Journal of Poultry Science, 2010 Coenzyme Q10 (CoQ10), a potent lipophilic antioxidant, is a naturally occurring compound with a ubiquitous distribution in nature and is used as a dietary supplement to combat aging.
Kazuhisa Honda +4 more
doaj +1 more source
Coenzyme A thiosulfonate (coenzyme A disulfide-S,S-dioxide), an affinity analog of coenzyme A.
Journal of Biological Chemistry, 1982 The structure of the CoA affinity analog-oxidized CoA disulfide (o-CoAS2) (Collier, G. E., and Nishimura, J. S. (1978) J. Biol. Chem. 253, 4938-4939) has been deduced to be that of the thiosulfonate of CoA, i.e. coenzyme A disulfide-S,S-dioxide. This deduction is based on several considerations among which are: the cleavage of o-CoAS2 by dithiothreitol
J S, Nishimura +3 more
openaire +2 more sources
Antioxidant Supplementation in the Treatment of Aging-Associated Diseases [PDF]
, 2016 Oxidative stress is generally considered as the consequence of an imbalance between pro- and antioxidants species, which often results into indiscriminate and global damage at the organismal level.
Conti, V +7 more
core +2 more sources
Coenzyme A in Brain Biology and Neurodegeneration
BiomedicinesCoenzyme A (CoA) biology has been extensively studied in health and disease due to the central role of CoA in numerous metabolic and signalling processes.
Dejun Zhang +4 more
doaj +1 more source