Results 61 to 70 of about 248,704 (239)

Cardiorenal Involvement in Metabolic Syndrome Induced by Cola Drinking in Rats: Proinflammatory Cytokines and Impaired Antioxidative Protection [PDF]

open access: yes, 2016
We report experimental evidence confirming renal histopathology, proinflammatory mediators, and oxidative metabolism induced by cola drinking. Male Wistar rats drank ad libitum regular cola (C, = 12) or tap water (W, = 12). Measures.
Ambrosio, Giuseppe   +7 more
core   +1 more source

A Case of Statin-Associated Autoimmune Myopathy. [PDF]

open access: yes, 2017
A 70-year-old previously independent man developed progressive proximal leg weakness resulting in a fall at home suffering traumatic brain injury. He was prescribed a statin medication two years prior, but this was discontinued on admission to the ...
Dokukin, Andrei N   +6 more
core   +3 more sources

Knock-down of pantothenate kinase 2 severely affects the development of the nervous and vascular system in zebrafish, providing new insights into PKAN disease

open access: yesNeurobiology of Disease, 2016
: Pantothenate Kinase Associated Neurodegeneration (PKAN) is an autosomal recessive disorder with mutations in the pantothenate kinase 2 gene (PANK2), encoding an essential enzyme for Coenzyme A (CoA) biosynthesis.
Daniela Zizioli   +10 more
doaj   +1 more source

Evaluation of The Analgesic Activity of Coenzyme Q10 Ointment in Mice

open access: yesJournal of Applied Veterinary Sciences, 2020
The aim of this study is to examine analgesic effect of Coenzyme Q10 ointment in mice. Fifteen healthy male albino mice were selected for this study. The animals were divided into three groups of five animals for each group.
Ibtisam T. Al-Jureisy   +2 more
doaj   +1 more source

Effects of ursodeoxycholic acid on synthesis of cholesterol and bile acids in healthy subjects [PDF]

open access: yes, 2004
Background/Aims: Ursodeoxycholic acid ( UDCA) decreases biliary secretion of cholesterol and is therefore used for the dissolution of cholesterol gallstones.
Fischer, S.   +5 more
core   +1 more source

THE IMPACT OF CARDIOVASCULAR AND BRONCHOPULMONARY DISEASES ON COENZYME Q10 PLASMA CONCENTRATION

open access: yesСеченовский вестник, 2019
Introduction. Coenzyme Q10 plays an important role in the human body. Its main function is not only the transfer of electrons in the mitochondrial respiratory chain for the ATP synthesis, but it is also one of the most powerful antioxidants in the body ...
V. I. Zozina   +4 more
doaj   +1 more source

Associations between Coenzyme Q10 Status, Oxidative Stress, and Muscle Strength and Endurance in Patients with Osteoarthritis

open access: yesAntioxidants, 2020
Osteoarthritis (OA) causes oxidative stress. Coenzyme Q10 is an antioxidant that participates in energy production in the human body. The purpose of this study was to investigate the relationships among coenzyme Q10 status, oxidative stress, antioxidant ...
Po-Sheng Chang   +4 more
doaj   +1 more source

Insights into the Ecological Roles and Evolution of Methyl-Coenzyme M Reductase-Containing Hot Spring Archaea [PDF]

open access: yes, 2019
Several recent studies have shown the presence of genes for the key enzyme associated with archaeal methane/alkane metabolism, methyl-coenzyme M reductase (Mcr), in metagenome-assembled genomes (MAGs) divergent to existing archaeal lineages.
Chen, Ya-Ting   +17 more
core   +2 more sources

4′‐Phosphopantetheine corrects CoA, iron, and dopamine metabolic defects in mammalian models of PKAN

open access: yesEMBO Molecular Medicine, 2019
Pantothenate kinase‐associated neurodegeneration (PKAN) is an inborn error of CoA metabolism causing dystonia, parkinsonism, and brain iron accumulation.
Suh Young Jeong   +22 more
doaj   +1 more source

Role of mitochondria in neuronal cell death induced by oxidative stress; neuroprotection by Coenzyme Q10

open access: yesNeurobiology of Disease, 2005
Neuronal cells depend on mitochondrial oxidative phosphorylation for most of their energy needs and therefore are at a particular risk for oxidative stress.
M. Somayajulu   +5 more
doaj   +1 more source

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