Heart Failure—Do We Need New Drugs or Have Them Already? A Case of Coenzyme Q10
Heart failure (HF) is a global epidemic that contributes to the deterioration of quality of life and its shortening in 1–3% of adult people in the world. Pharmacotherapy of HF should rely on highly effective drugs that improve prognosis and prolong life.
Krzysztof J. Filipiak+3 more
doaj +1 more source
Primary Coenzyme Q10 Deficiency [PDF]
open4siCLINICAL CHARACTERISTICS: Primary coenzyme Q10 (CoQ10) deficiency is usually associated with multisystem involvement, including neurologic manifestations such as fatal neonatal encephalopathy with hypotonia; a late-onset slowly progressive ...
Doimo, Mara+3 more
core
Covalent Organic Frameworks for Photocatalysis
This review provides an overview of recent advances in covalent organic frameworks (COFs) for photocatalysis, focusing on sustainable energy applications like water splitting, hydrogen peroxide generation, and CO2 and N2 reduction. It discusses design principles, structure‐function relationships, challenges in COF photocatalysis, and strategies to ...
Bikash Mishra+6 more
wiley +1 more source
Regulator of Fatty Acid Metabolism, Acetyl Coenzyme A Carboxylase 1, Controls T Cell Immunity
Fatty acids (FAs) are essential constituents of cell membranes, signaling molecules, and bioenergetic substrates. Because CD8+ T cells undergo both functional and metabolic changes during activation and differentiation, dynamic changes in FA metabolism ...
JangEun Lee+5 more
semanticscholar +1 more source
Auxotrophic Selection Strategy for Improved Production of Coenzyme B12 in Escherichia coli
Summary: The production of coenzyme B12 using well-characterized microorganisms, such as Escherichia coli, has recently attracted considerable attention to meet growing demands of coenzyme B12 in various applications. In the present study, we designed an
Myung Hyun Noh+4 more
doaj
The physiological significance of the water soluble components of nervous tissue [PDF]
Part I. The mechanisms of acetylcholine synthesis1) Both citrate and acetate can act as acetyl donors for choline acetylation by crude brain extracts.2) In order to demonstrate the action of acetate three conditions have to be observed: a) that ...
Balfour, W. E.
core +1 more source
Remnants of an ancient metabolism without phosphate [PDF]
Phosphate is essential for all living systems, serving as a building block of genetic and metabolic machinery. However, it is unclear how phosphate could have assumed these central roles on primordial Earth, given its poor geochemical accessibility.
Goldford, Joshua E.+3 more
core +1 more source
Continuous Flow Technology Enabling Photochemistry
The merger of continuous flow technology and modern photochemistry has enabled countless applications showcasing new opportunities for chemical synthesis demonstrating improvements in selectivity, safety, sustainability and scalability. This focused review aims to highlight a selection of recently published case studies from academic and industrial ...
Ruairi Crawford, Marcus Baumann
wiley +1 more source
Faithful flatness of Hopf algebras over coideal subalgebras with a conditional expectation [PDF]
Let $H$ be a Hopf algebra and let $A\subset H$ be a right coideal subalgebra. We show that if $A$ is a direct summand in $H$ as a right $A$-module, then $H$ is faithfully flat as a right $A$-module.
arxiv
Correlation between vitamin A, E, coenzyme Q10 and degree of insulin resistance in obese and non-obese subjects [PDF]
The aim of the present study was to investigate correlation between plasma vitamin A, vitamin E, serum coenzyme Q10 levels and degree of insulin resistance in obese and normal weight people. The study was performed on 98 (21 Male, 77 Female) obese people
AASHEIM ERLEND T+4 more
core +2 more sources