Results 241 to 250 of about 1,577,940 (309)

Müller Glial Kir4.1 Channel Dysfunction in APOE4‐KI Model of Alzheimer's Disease

Glia, Volume 74, Issue 3, March 2026.
APOE4 impairs Müller cell health by reducing Kir4.1 expression and buffering. APOE4 causes mitochondrial dysfunction with decreased ΔΨm and increased ROS. MitoQ restores Kir4.1 expression and reduces ROS in APOE4‐transfected cells. ABSTRACT Alzheimer's disease (AD), particularly late‐onset AD (LOAD), affects millions worldwide, with the apolipoprotein ...
Surabhi D. Abhyankar, Yucheng Xiao, Neha Mahajan, Qianyi Luo, Theodore R. Cummins, Adrian L. Oblak, Bruce T. Lamb, Timothy W. Corson, Ashay D. Bhatwadekar   +8 more
wiley   +1 more source

Elevated Salivary Antioxidant Biomarkers are Favorable for Clinical Pregnancy in Women Undergoing IVF: A Prospective Cohort Study

Health Science Reports, Volume 9, Issue 3, March 2026.
ABSTRACT Background and Aims The imbalance of oxidants and antioxidants mediates cell damage through a phenomenon known as oxidative stress. The increase in fertility problems led to a growing focus on factors that affect the outcome of reproductive‐ assisted treatments.
Mahdieh Ghafarpoor, Narges Gholizadeh, Ashraf Alyasin, Iraj Mirzaii‐Dizgah, Mohadeseh Bahmaee, Nafiseh Sheykhbahaei   +5 more
wiley   +1 more source

Coenzyme Q₄ is a functional substitute for coenzyme Q₁₀ and can be targeted to the mitochondria. [PDF]

J Biol Chem
Steenberge LH, Rogers S, Sung AY, Fan J, Pagliarini DJ.   +4 more
europepmc   +1 more source

Oleoylethanolamide regulates intestinal stem cell activity and villus size via PPARα signaling pathway

iMetaOmics, Volume 3, Issue 1, March 2026.
First use of a natural swine model with lipid metabolism to directly link lipid differences to a quantifiable intestinal villus height phenotype. Identified the phospholipid‐derived oleoylethanolamide, rather than canonical fatty acids, as the endogenous primary ligand that activates peroxisome proliferator‐activated receptors α (PPARα) to enlarge ...
Qianqian Wang, Lanmei Yin, Zhaobin Wang, Jun Li, Xianglin Zeng, Qiye Wang, Jianzhong Li, Kang Xu, Huansheng Yang, Yulong Yin   +9 more
wiley   +1 more source

Association between coenzyme Q 10-related genetic polymorphisms and statin-associated myotoxicity in Korean stroke patients. [PDF]

Front Pharmacol
Park YA, Chang Y, Lee DH, Kim JS, Park M, Choi SA, Song TJ, Gwak HS.   +7 more
europepmc   +1 more source

Biosynthesis gene cluster‐containing species drive microbial community stability under thermal stress through enhanced ecological cohesion

iMetaOmics, Volume 3, Issue 1, March 2026.
The study framework for exploring microbial community assembly and community stability of biosynthesis gene cluster (BGC)‐containing species under thermal stress (20°C–65°C) during 39 days of spontaneous fermentation. Temperature gradients during spontaneous fermentation reshape microbial community assembly, driving pronounced succession in both ...
Shibo Ban, Binghao He, Yang Song, Xin Li An, Yan Xu, Qun Wu, Yu Shi   +6 more
wiley   +1 more source

Exploring Plasma Coenzyme Q₁₀ Status in Paediatric Dyslipidaemia. [PDF]

Antioxidants (Basel)
Minguez B, de Los Santos M, Garcia-Volpe C, Molera C, Paredes-Fuentes AJ, Oliva C, Arias A, Rodriguez-Gonzalez H, Yubero D, Tondo M, Santos-Ocaña C, Meavilla S, Artuch R.   +12 more
europepmc   +1 more source

Reduced Dietary Protein Induces Changes in the Dental Proteome

Journal of Experimental Zoology Part B: Molecular and Developmental Evolution, Volume 346, Issue 2, Page 107-127, March 2026.
Low dietary protein (10%) from normal (20%) does change protein expression in tooth proteome and alter developmental pathways. Among the significant protein expressions changes are actin‐based myosins, tooth, and bone development proteins. Perplexingly tooth size is not altered, suggesting more nuanced phenotypic response to low dietary protein in ...
Robert W. Burroughs, Christopher J. Percival, Natasha S. Vitek   +2 more
wiley   +1 more source

Studies on Coenzyme Q

Journal of Biological Chemistry, 1965
Ronald Bentley, W.V. Lavate
openaire   +1 more source