Lifestyle implications of the paradox and management of oxidative stress in sperm
The Journal of Physiology, EarlyView.Abstract figure legend Lifestyle factors influencing male fertility. Schematic overview of lifestyle factors with beneficial (left) and detrimental (right) effects on male fertility. A balanced diet, regular moderate physical activity and stress management strategies support sperm function and redox homeostasis.
Giuseppe T. Patané +6 more
wiley +1 more source
Statins in Breast Cancer Therapy: Mechanistic Insights and Emerging Evidence
Cancer Innovation, Volume 5, Issue 1, February 2026.Statins, particularly simvastatin, demonstrate potential as adjuvant agents in breast cancer treatment by disrupting tumour cell signalling and survival pathways. This review highlights emerging evidence supporting their repurposing for improved outcomes, especially in aggressive breast cancer subtypes.
Rohina Alim, H. M. Kasuni Akalanka
wiley +1 more source
Short-term impact of aged garlic extract on endothelial function in diabetes: A randomized, double-blind, placebo-controlled trial. [PDF]
, 2020 Impaired endothelial function portends an increased risk of cardiovascular disease. Vascular oxidative stress and systemic inflammation play a critical role in the pathogenesis and progression of vascular disease.
Birudaraju, Divya +9 more
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EFFECT OF COENZYME Q10 AND L-CARNITINE ON GROWTH PERFORMANCE, PHYSICAL AND CHEMICAL BLOOD INDICES, ANTIOXIDANT STATUS AND IMMUNE RESPONSE OF NEWBORN EGYPTIAN BUFFALO CALVES [PDF]
, 2020 A. Gabr
openalex +1 more source
Oxidative Stress: Molecular Mechanisms, Diseases, and Therapeutic Targets
MedComm, Volume 7, Issue 2, February 2026.Oxidative stress occurs when the reactive oxygen species (ROS) production overwhelms the ROS scavenging, which lead to genomic instability, epigenetic regulation, proteostasis imbalance, and lipid peroxidation, subsequently causing the occurrence and development of numerous diseases. ABSTRACT Although the physiological level of reactive oxygen species (
Yi Qin +10 more
wiley +1 more source
Endothelial dysfunction and inflammatory biomarkers as a response factor of concurrent coenzyme Q10 add-on metformin in patients with type 2 diabetes mellitus [PDF]
, 2019 Hayder M. Al‐kuraishy +3 more
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Diabetes, Obesity and Metabolism, Volume 28, Issue 2, Page 826-839, February 2026.Abstract Maternally inherited diabetes and deafness (MIDD) is a mitochondrial disorder usually caused by the variant m.3243A>G in the MT‐TL1 gene. We have proposed that diabetes in MIDD arises from a combination of insulin resistance and impaired β‐cell function that is more likely to occur in the presence of high skeletal muscle heteroplasmy and ...
Ahsen Chaudhry +2 more
wiley +1 more source
The effect of coenzyme Q10 on the state hemostasis in the blood of old animals in high-altitude conditions [PDF]
E3S Web of ConferencesIn this study, the effect of oral administration of coenzyme Q10 on the blood coagulation system parameters in old rats under low- and high-altitude conditions was investigated.
Gulbarchyn Alisherovna Asrankulova +5 more
doaj +1 more source
Statins: Adherence and side-effects [PDF]
, 2016 Many patients either do not adhere to, or fail to persist with, long-term lipid-lowering therapy. This unfavourable medication utilisation behaviour compromises potential treatment benefit.
Blom, D J
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مجلة كلية الطبBackground: Rheumatoid arthritis (RA) is a chronic inflammatory autoimmune illness. Oxidative stress such as Malondialdehyde plays a major role in the pathophysiology of RA while antioxidants such as Coenzyme Q10 play protect role against inflammation.
Nagham Y. Mohsin +2 more
doaj +1 more source