Results 101 to 110 of about 96,183 (271)
Inherited metabolic epilepsies–established diseases, new approaches
Epilepsia Open, EarlyView.Abstract Inherited metabolic epilepsies (IMEs) represent the inherited metabolic disorders (IMDs) in which epilepsy is a prevailing component, often determining other neurodevelopmental outcomes associated with the disorder. The different metabolic pathways affected by individual IMEs are the basis of their rarity and heterogeneity.
Itay Tokatly Latzer, Phillip L. Pearl
wiley +1 more source
The role of Coenzyme Q10 in statin-associated myopathy [PDF]
, 2009 Statins, or 3-hydroxyl-3-methylglutaryl coenzyme HMG-CoA reductase inhibitors,\ud are cholesterol-lowering drugs which are frequently used in the primary and secondary\ud prevention of coronary artery disease. Current research and recommendations support\
Kalra, Dr Sanjay
core
Interdisciplinary Medicine, EarlyView.This review highlights recent advances in mitochondria‐targeted nanomedicine for cancer therapy. It summarizes key targeting strategies and delineates four principal therapeutic mechanisms: oxidative stress–induced mitochondrial dysfunction, disruption of energy metabolism, direct mitochondrial damage, and induction of immunogenic cell death.
Linfeng Xiao +7 more
wiley +1 more source
The importance of the formulation in the effectiveness of Coenzyme Q10 supplementation in mitochondrial disease therapy [PDF]
, 2012 This report describes the response of a patient treated with two different coenzyme Q10 extemporaneous pharmaceutical formulations that generated radical changes in her symptoms and life quality.
Lucangioli, Silvia Edith +1 more
core
Forest plot of comparisons of Coenzyme Q10 supplementation versus placebo (outcomes: A: serum Coenzyme Q10, B: tumor necrosis factor-alpha, C: interleukin-6, D: C reactive protein). [PDF]
, 2017 Forest plot of comparisons of Coenzyme Q10 supplementation versus placebo (outcomes: A: serum Coenzyme Q10, B: tumor necrosis factor-alpha, C: interleukin-6, D: C reactive protein).
Lishi Zhang (3710122) +4 more
core +1 more source
The Effect of Zinc and Coenzyme Q10 Supplementation in Combination with Vitamin C on Lead Acetate-Induced Testicular Injury and Oligospermia in Rats [PDF]
International Journal of Nutrition SciencesBackground: Male infertility means that a man cannot start a pregnancy with the female partner. In this relation, the fatal impact of environment factors such as heavy metals was reported a worldwide concern.
Muhsin SG Al-Mozie’l
doaj +1 more source
Mass Spectrometry Reviews, EarlyView.ABSTRACT Nitrooxidative stress, driven by excess reactive nitrogen species like peroxynitrite, contributes to the pathogenesis of many chronic diseases. Among its molecular footprints, 3‐nitrotyrosine (3NT) has emerged as a biologically relevant marker of protein nitration.
Brîndușa Alina Petre
wiley +1 more source
The antioxidant status of coenzyme Q10 and vitamin E in children with type 1 diabetes
Jornal de Pediatria, 2019 Objective: The purpose of this study was to evaluate the antioxidant status of plasma vitamin E and plasma and intracellular coenzyme Q10 in children with type 1 diabetes.
Usama M. Alkholy +6 more
doaj +3 more sources
Journal of Oral Biology and Craniofacial Research, 2019 Background: Coenzyme Q10 is an antioxidant whose efficacy in periodontal diseases is well known. However studies regarding its efficacy in smokers with periodontitis are few.
Chetan P. Raut +4 more
doaj +1 more source
Isothiocyanates as Ferroptosis Inducers to Promote Cancer Cell Death
Phytotherapy Research, EarlyView.ABSTRACT Cancer remains a leading cause of global mortality, with the therapeutic efficacy of anticancer drugs often hampered by late diagnosis and the development of chemotherapy resistance. Ferroptosis is an iron‐dependent form of regulated non‐apoptotic cell death driven by lipid peroxidation.
Valentina Citi +6 more
wiley +1 more source