Effectiveness of Riboflavin in Inherited Metabolic Diseases: A Systematic Review
ABSTRACT Riboflavin (RF, vitamin B2) is an essential vitamin of which the co‐factors are critical to numerous cellular processes. RF is used as a treatment for inherited metabolic diseases (IMDs), although its effectiveness in many disorders has not been established.
Bregje Jaeger +7 more
wiley +1 more source
Current experience in testing mitochondrial nutrients in disorders featuring oxidative stress and mitochondrial dysfunction: rational design of chemoprevention trials [PDF]
An extensive number of pathologies are associated with mitochondrial dysfunction (MDF) and oxidative stress (OS). Thus, mitochondrial cofactors termed “mitochondrial nutrients” (MN), such as α-lipoic acid (ALA), Coenzyme Q10 (CoQ10), and l-carnitine ...
Castello, Giuseppe +5 more
core
CoQ10 and vitamin A supplementation support voice rehabilitation. A double-blind, randomized, controlled, three-period cross-over pilot study [PDF]
Objectives: To evaluate the effectiveness of an adjuvant therapy (CoQ10 in its watersoluble form and vitamin A) in supporting voice rehabilitation in a large group of patients with muscle tension dysphonia (MTD).
de Vincentiis, M +8 more
core +1 more source
The research objective consisted in studying of influence of coenzyme Q10 as a part of complex therapy of patients with the chronic heart failure (CHF) on indicators of quality of life in comparison with traditional therapy without coenzyme Q10 addition.
Zh. M. Sizova +2 more
doaj +1 more source
Long‐Term Stress Adaptation as a Highly‐Conserved Key Factor in Yeast Aging
This study shows that long‐term, but not short‐term, stress exposure triggers molecular changes in yeast that mirror established hallmarks of aging, including altered proteostasis, epigenetic shifts, and reduced lifespan. These changes are reversible upon stress removal, and the genes involved are conserved across all domains of life. ABSTRACT Aging is
Yanzhuo Kong +7 more
wiley +1 more source
The effects of coenzyme Q10 supplementation on gene expression related to insulin, lipid and inflammation in patients with polycystic ovary syndrome [PDF]
Objective: This research was conducted to assess the effects of coenzyme Q10 (CoQ10) intake on gene expression related to insulin, lipid and inflammation in subjects with polycystic ovary syndrome (PCOS).
Aghadavod, Esmat +7 more
core
Autoimmune diseases are a heterogeneous group of afflictions whose etiopathogenesis is still incompletely understood. There is a great need to search for new treatment methods because of the difficulty of treatment, the numerous side effects of ...
Martyna Bukała +9 more
doaj +1 more source
This study identifies ferroptosis as a key driver of diabetes and its complications via iron metabolism and lipid peroxidation, elucidates organelle interactions underlying cell vulnerability, and provides insights for targeted therapies against metabolic disorders.
Zheng Wang +10 more
wiley +1 more source
Aged garlic extract reduces low attenuation plaque in coronary arteries of patients with diabetes: A randomized, double-blind, placebo-controlled study. [PDF]
Several previous studies have demonstrated that aged garlic extract (AGE) inhibits the progression of coronary artery calcification and non-calcified plaque (NCP) in the general population.
Almeida, Shone +13 more
core
The Antioxidant Status and Concentrations of Coenzyme Q10 and Vitamin E in Metabolic Syndrome
The purpose of this study was to investigate the levels of coenzyme Q10 and vitamin E and the antioxidant status in subjects with metabolic syndrome (MS). Subjects with MS (n=72) were included according to the criteria for MS.
Chi-Hua Yen +5 more
doaj +1 more source

