Results 111 to 120 of about 33,314 (243)

Atorvastatin therapy and antioxidant status correction in patients with metabolic syndrome

Российский кардиологический журнал, 2013
Aim. To study the changes in antioxidant status and glucose-insulin homeostasis among atorvastatin-treated patients with metabolic syndrome and to investigate the potential of coenzyme Q10 for the correction of these changes. Material and methods.
N. S. Yubitskaya, M. V. Antonyuk, V. I. Yankova   +2 more
doaj   +1 more source

A Case Series of Sudden Death in Children Aged 12 Months to 4 Years From LPIN1 Deficiency and PPA2 Deficiency in Queensland

Journal of Paediatrics and Child Health, EarlyView.
Sophie Manoy, Sally Smith, Marita Smith, Catherine Atthow, Janette Spicer, Matthew Lynch, Michelle Lipke, Julie A. McEniery, David Coman, Anita Inwood, Jim McGill, Carolyn Bursle   +11 more
wiley   +1 more source

BPM31510 Increases the CoQ Pool in Chemically Induced CoQ‐Deficient Cells, CoQ‐Deficient Patient Fibroblasts, and in Metabolically Active Murine Tissues

The FASEB Journal, Volume 40, Issue 7, 15 April 2026.
Graphical abstract illustrating the in vitro and in vivo experimental workflow used to compare BPM31510, a nanoliposomal formulation of oxidized CoQ10, with conventional CoQ10. Chemically induced CoQ‐deficient SH‐SY5Y cells, CoQ‐deficient patient fibroblasts, and C57BL/6J mice receiving oral CoQ10 or intraperitoneal BPM31510 were subjected to plasma ...
Juan J. Aristizabal‐Henao, Sarah R. Wessel, Sylwia A. Stopka, Srada Karmacharya, Devon Van Cura, Alba Pesini, Kelsey R. Nickerson, Kashni Grover, Oksana Zavidij, Archna Ravi, Andressa L. Mota, Kenneth M. Rosen, Maria‐Dorothea Nastke, Megan K. Cox, Niven R. Narain, Vijay Modur, Catarina M. Quinzii, Stephane Gesta, Michael A. Kiebish   +18 more
wiley   +1 more source

Tim1 Deficiency Mediates Gestational Hyperglycemia‐Related Syncytiotrophoblast Dysfunction and Fetal Growth Restriction

Advanced Science, Volume 13, Issue 20, 9 April 2026.
Hyperglycemia during pregnancy impairs the fusion of trophoblast cells into syncytiotrophoblasts, leading to fetal growth restriction. This impaired fusion is mediated by Tim1 downregulation via hyperglycemia‐induced ROS. Antioxidant therapy during pregnancy promotes syncytiotrophoblast formation by upregulating Tim1 expression, thus alleviating fetal ...
Junsen She, Rui Liu, Chen Fang, Shuyu Zhang, Yizhi Hu, Fei Guo, Yuhang Long, Mengzhen Ding, Haiyan Wu, Bokang Zhou, Zexin Yang, Ying Jiang, Jianzhong Sheng, Ling Gao, Hefeng Huang   +14 more
wiley   +1 more source

Palmitoylation‐Mediated Ubiquitination of SRPK1 Regulates Ferroptosis in High‐Fat‐Induced Erectile Dysfunction

Advanced Science, Volume 13, Issue 19, 2 April 2026.
Elevated exogenous palmitic acid promotes the S‐palmitoylation of SRPK1 in endothelial cells, a dynamic process governed by ZDHHC24 and APT1. This post‐translational modification strengthens the interaction between SRPK1 and the E3 ubiquitin ligase MIB1, thereby facilitating the proteasomal degradation of SRPK1.
Xiao‐Hui Tan, Ke‐Fan Li, Yi‐Ming Yuan, Man‐Cheng Xia, Fang‐Zhou Zhao, Hong‐Gang Ying, Zhuo Zhou, Peng‐Chao Gao, Guo‐Qing Xie, Xue‐Song Li, Hui Jiang, Rui‐Li Guan   +11 more
wiley   +1 more source

Impact of Biologic and Conventical Synthetic DMARDs on Serum Coenzyme Q10 and Malondialdehyde in Rheumatoid Arthritis Patients

مجلة كلية الطب
Background: Rheumatoid arthritis (RA) is a chronic inflammatory autoimmune illness. Oxidative stress such as Malondialdehyde plays a major role in the pathophysiology of RA while antioxidants such as Coenzyme Q10 play protect role against inflammation.
Nagham Y. Mohsin, Basil O. Saleh, Faiq I. Gorial   +2 more
doaj   +1 more source

Protection and Delivery of Phytochemicals from Passive Encapsulation to Guaranteed Self‐Assembly Induced by Amyloid Template for Chronic Disease Prevention via Modulating Microbial‐Host Crosstalk

Advanced Science, Volume 13, Issue 21, 13 April 2026.
ABSTRACT The rising incidence of chronic diseases globally has drawn widespread attention to phytochemicals, which exert targeted preventive and alleviating effect by modulating gut microbiota; thus, a potential strategy for precision nutritional interventions is offered.
Shiqi Bai, Siying Cheng, Fengguang Ma, Xiaorong Zhang, Jianan Huang, Zhonghua Liu, Bing Hu   +6 more
wiley   +1 more source

Effect of some natural antioxidants on aflatoxin B1-induced hepatic toxicity [PDF]

, 2008
Aflatoxins are potent hepatotoxic and hepatocarcinogenic agents. This hepatotoxicity is thought to be mediated by their ability to generate reactive oxygen species and cause peroxidative damage.
Kheir Eldin, Adel A., Motawi, Tarek M. K., Sadik, Nermin A. H.   +2 more
core  

Genome‐Wide Association Studies for 24 Hematological Traits in Production Pigs Before and After Weaning

Animal Genetics, Volume 57, Issue 2, April 2026.
ABSTRACT Hematological traits are essential indicators of an animal's immune status and overall health, reflecting both physiological and pathological conditions. The complete blood count (CBC), a commonly used clinical test, evaluates the concentrations, proportions, and characteristics of various blood cell parameters, providing insights into an ...
Jiahong Sun, Emil Ibragimov, Malene Kjelin Morsing, Martin Peter Rydal, Lise Nikolic Nielsen, Zexi Cai, Jens Peter Nielsen, Merete Fredholm, Peter Karlskov‐Mortensen   +8 more
wiley   +1 more source

Coenzyme Q10

, 2012
europepmc   +3 more sources