Results 121 to 130 of about 33,314 (243)

Ferroptotic neurodegeneration and diet: a narrative review

open access: yesAlzheimer's &Dementia, Volume 22, Issue 4, April 2026.
Dietary regimes and separate components have been reported to reduce ferroptosis by (1) altering iron metabolism, (2) increasing antioxidant defense, and (3) reducing lipid peroxidation. This ultimately leads to reduced ferroptosis and neurodegeneration.
Ximaine R. van der Burg   +4 more
wiley   +1 more source

An Overview of Leber’s Hereditary Optic Neuropathy [PDF]

open access: yes, 2015
Typically affecting males ranging from 20 to 24 years of age, Leber’s Hereditary Optic Neuropathy (LHON) is a disorder that is characterized by an acute loss of central vision.
Dalton, Matthew R
core   +2 more sources

Decoding the Pathophysiology of Autoimmune Diseases—Mechanism, Triggers, and Nanotherapeutics: A Review

open access: yesAdvanced NanoBiomed Research, Volume 6, Issue 4, April 2026.
This review highlights how autoimmune diseases arise from intertwined immunological, genetic, and environmental factors, emphasizing gut microbiota dysbiosis as a pivotal driver. It outlines emerging nanotechnology‐based strategies—such as liposomes, hydrogels, and polymeric nanoparticles—that enhance targeted drug delivery, minimize systemic toxicity,
Md. Meraj Ansari   +5 more
wiley   +1 more source

Short-term impact of aged garlic extract on endothelial function in diabetes: A randomized, double-blind, placebo-controlled trial. [PDF]

open access: yes, 2020
Impaired endothelial function portends an increased risk of cardiovascular disease. Vascular oxidative stress and systemic inflammation play a critical role in the pathogenesis and progression of vascular disease.
Birudaraju, Divya   +9 more
core  

Predicting Potential Treatment Targets for Fatigue in Chronic Fatigue Syndrome Using Thalamic Seeding

open access: yesBrain and Behavior, Volume 16, Issue 4, April 2026.
Bilateral thalamic seeding identified a candidate cortical target near PO7 in the left lateral occipital cortex. Its FC correlated with fatigue severity and exercise‐induced fatigue in CFS, suggesting an FC‐guided framework for future NIBS targeting fatigue symptoms.
Kang Wu   +7 more
wiley   +1 more source

Anticancer Potential of Piericidin A1 and Derivatives Isolated From Streptomyces sp. Associated With Palythoa variabilis From Brazilian Reefs

open access: yesChemistry &Biodiversity, Volume 23, Issue 4, April 2026.
A Streptomyces spp. strain, isolated from the zoantharian Palythoa variabilis, produces the complex I mitochondrial inhibitor piericidin A1 with effects on cancer cells proliferation and MTT‐formazan reduction at concentrations up to 0.1 aM. ABSTRACT Marine holobionts are an important source of bioactive natural products.
Bianca Del B. Sahm   +9 more
wiley   +1 more source

Food is our medicine [PDF]

open access: yes, 2012
The paper describes the role of foods and nutrition in the promotion of human health. The relationship between foods, metabolism, homeostasis and metabolic disorder are briefly described.
Sarmidi, Mohamad Roji
core  

Decades of Misdiagnosis as Myasthenia Gravis: Late‐Onset POLG‐Related Ophthalmoplegia Unveiled by Whole‐Genome Sequencing

open access: yesClinical Case Reports, Volume 14, Issue 4, April 2026.
ABSTRACT A 55‐year‐old male developed POLG‐related ophthalmoplegia in 2015 and was misdiagnosed with seronegative myasthenia gravis for 10 years. Whole‐genome sequencing identified compound heterozygous POLG mutations, highlighting its value in diagnosing refractory neuromuscular disorders.
Tanli Lu   +3 more
wiley   +1 more source

“Coenzyme Q10” (Coenzym Q10) [PDF]

open access: yesIIC - International Review of Intellectual Property and Competition Law, 2016
openaire   +1 more source

Spatial and single‐cell RNA sequencing reveals the immune microenvironment of human ascending thoracic aortic aneurysms

open access: yesClinical and Translational Medicine, Volume 16, Issue 4, April 2026.
This study has used integrated single‐cell RNA sequencing and Visium HD spatial transcriptomics to construct a high‐resolution immune cell atlas of human ascending thoracic aortic aneurysms (ATAA). The analysis reveals distinct immune cell composition and interactions in ATAA tissues, providing new insights into immune dysregulation and vascular ...
Ke Zhen   +6 more
wiley   +1 more source

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