Results 31 to 40 of about 36,139 (254)

Genetics of Coenzyme Q10 Deficiency [PDF]

open access: yesMolecular Syndromology, 2014
Coenzyme Q10 (CoQ10) is an essential component of eukaryotic cells and is involved in crucial biochemical reactions such as the production of ATP in the mitochondrial respiratory chain, the biosynthesis of pyrimidines, and the modulation of apoptosis. CoQ10 requires at least 13 genes for its biosynthesis.
DOIMO, MARA   +5 more
openaire   +3 more sources

Role of mitochondria in neuronal cell death induced by oxidative stress; neuroprotection by Coenzyme Q10

open access: yesNeurobiology of Disease, 2005
Neuronal cells depend on mitochondrial oxidative phosphorylation for most of their energy needs and therefore are at a particular risk for oxidative stress.
M. Somayajulu   +5 more
doaj   +1 more source

Substantiation of approaches to the correction of lipid metabolism disorders and non-alcoholic fatty liver disease in children with exogenous obesity

open access: yesОжирение и метаболизм, 2022
BACKGROUND: According to the involvement of oxidative stress in the pathogenesis of obesity, the plasma level of coenzyme q10 in the correlation relationship with lipid metabolism disorders and functional liver state is of interest to study.AIM ...
O. V. Povarova   +6 more
doaj   +1 more source

Protective effect of coenzyme Q10 supplementation on the oxidative stress and histological injury caused by nicotine in the ovary of rats [PDF]

open access: yesĀsīb/shināsī-i Darmāngāhī-i Dāmpizishkī, 2023
As a poison, nicotine leaves irreparable effects on various tissues of the body, including the reproductive system. Coenzyme Q10 has a tremendous effect in raising the body's antioxidant level and preventing poisoning.
Shahnaz Yousefizadeh   +2 more
doaj   +1 more source

Circulating levels of reactive oxygen species in patients with nonproliferative diabetic retinopathy and the influence of antioxidant supplementation: 6-month follow-up [PDF]

open access: yes, 2015
The aim was to evaluate circulating levels of reactive oxygen species (ROS) and changes in central macular thickness (CMT) in patients with nonproliferative diabetic retinopathy (NPDR) after antioxidant supplementation.
Carnevale, Carmela   +5 more
core   +4 more sources

Coenzyme Q10 Modulates Remodeling Possibly by Decreasing Angiotensin-Converting Enzyme in Patients with Acute Coronary Syndrome

open access: yesAntioxidants, 2018
The study aims to examine the effects of coenzyme Q10, (a bioenergetic antioxidant), on the indexes of left ventricular remodeling, oxidative damage, and angiotensin-converting enzyme (ACE) level after acute myocardial infarction (AMI) with left ...
Ram B. Singh   +3 more
doaj   +1 more source

Anti-oxidants in Parkinson's disease therapy: a critical point of view [PDF]

open access: yes, 2016
Parkinson's disease (PD) is a degenerative neurological syndrome, which is characterized by the preferential death of dopaminergic (DAergic) neurons in the SubstantiaNigra.
Beltramini, Mariano   +3 more
core   +2 more sources

Neuroprotective effect of hesperidin and its combination with coenzyme Q10 on an animal model of ketamine-induced psychosis: behavioral changes, mitochondrial dysfunctions, and oxidative stress

open access: yesFuture Journal of Pharmaceutical Sciences, 2022
Background Psychosis is a complex mental illness divided by positive symptoms, negative symptoms, and cognitive decline. Clinically available medicines are associated with some serious side effects which limit their use.
Naresh Kumar   +4 more
doaj   +1 more source

Antioxidant Supplementation in the Treatment of Aging-Associated Diseases [PDF]

open access: yes, 2016
Oxidative stress is generally considered as the consequence of an imbalance between pro- and antioxidants species, which often results into indiscriminate and global damage at the organismal level.
Conti, V   +7 more
core   +2 more sources

Metabolic Targets of Coenzyme Q10 in Mitochondria [PDF]

open access: yesAntioxidants, 2021
Coenzyme Q10 (CoQ10) is classically viewed as an important endogenous antioxidant and key component of the mitochondrial respiratory chain. For this second function, CoQ molecules seem to be dynamically segmented in a pool attached and engulfed by the super-complexes I + III, and a free pool available for complex II or any other mitochondrial enzyme ...
Agustín Hidalgo-Gutiérrez   +6 more
openaire   +7 more sources

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