Results 61 to 70 of about 51,495 (221)

The antioxidant status of coenzyme Q10 and vitamin E in children with type 1 diabetes

Jornal de Pediatria, 2019
Objective: The purpose of this study was to evaluate the antioxidant status of plasma vitamin E and plasma and intracellular coenzyme Q10 in children with type 1 diabetes.
Usama M. Alkholy, Nermin Abdalmonem, Ahmed Zaki, Mohamed A. Elkoumi, Mustafa I. Abu Hashim, Maha A.A. Basset, Hossam E. Salah   +6 more
doaj   +3 more sources

Subgingivally delivered coenzyme Q10 in the treatment of chronic periodontitis among smokers: A randomized, controlled clinical study

Journal of Oral Biology and Craniofacial Research, 2019
Background: Coenzyme Q10 is an antioxidant whose efficacy in periodontal diseases is well known. However studies regarding its efficacy in smokers with periodontitis are few.
Chetan P. Raut, Kunal S. Sethi, Bhagyashree Kohale, Alefiya Mamajiwala, Ayushya Warang   +4 more
doaj   +1 more source

Renal‐vascular axis: unmasking its role in vascular endothelial growth factor‐inhibitor vascular toxicity in cancer patients

British Journal of Pharmacology, EarlyView.
Abstract Vascular toxicity is a growing concern in cancer patients receiving vascular endothelial growth factor inhibitor (VEGFi) therapy, posing a significant threat to patient prognosis. While the primary mechanism of VEGFi‐induced vascular toxicity is linked to redox‐sensitive reactions that disrupt vascular tone, leading to hypertension and ...
Grace Whelan, Karla B. Neves
wiley   +1 more source

Coenzyme q10 is potentially usedto improve lipid profile in diabetic hypercholesterolemia-induced periodontitis in the coastal area

E3S Web of Conferences, 2018
Contaminated water often affects the occurrence of periodontitis in the coastal area. The diabetic hypercholesterolemia-induced periodontitis in Indonesia is very high.
Saryono Saryono, Devinta Hesti, Widodo Abdul Haris Budi, Hidayat Arif Imam   +3 more
doaj   +1 more source

Metabolic remodelling in anthracycline cardiotoxicity: mechanisms and therapeutic insights

British Journal of Pharmacology, EarlyView.
Cardiac metabolic remodelling in anthracycline‐induced cardiomyopathy and metabolically oriented cardioprotective strategies. Schematic representation of substrate utilization, mitochondrial bioenergetic function and metabolic flexibility in the healthy heart, in anthracycline‐induced cardiomyopathy and under potential cardioprotective interventions ...
Giulia Guerra, Francesco Niro, Marco Mergiotti, Giovanni Gavatorta, Emilio Hirsch, Alessandra Ghigo   +5 more
wiley   +1 more source

THE MODERN METHODS OF ANALYSIS OF OXIDIZED AND REDUCED FORMS OF COENZYME Q₁₀ IN BIOMATERIAL (REVIEW)

Разработка и регистрация лекарственных средств, 2019
In the human body, coenzyme Q10 is in the oxidized and reduced forms and can be found in every organ. The review describes modern HPLC methods of coenzyme Q10 analysis using electrochemical, spectrophotometric and mass spectrometric detectors.
V. I. Zozina, O. A. Goroshko, L. M. Krasnykh, V. G. Kukes   +3 more
doaj  

An Evaluation of the Protective Effects of Coenzyme Q10 on Fertility Parameters of Male Mice Treated with Methotrexate [PDF]

Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul, 2023
Background and Objective: Methotrexate (MTX) is a chemotherapy drug that has destructive effects on body tissues, including the male reproductive system.
M Babaei, A Kalantari-Hesari, M Yavari, M Hallaj, H Morovvati   +4 more
doaj  

A 3D Bioprinted Platform That Maintains the Functional Integrity of Primary AML Cells

Cell Proliferation, EarlyView.
This study presents a 3D bioprinted platform using gelatin‐hyaluronic acid hydrogels to enhance primary AML cell survival and proliferation while preserving stem‐like properties in vitro. By recapitulating in vivo‐like metabolic activity and drug resistance, this system offers a robust tool for preclinical drug screening and personalised therapy ...
Wanling Huang, Bo Deng, Nini Guo, Yiyi Ding, Zhangjingwen Xu, Yiwen Lu, Yue Ma, Qian Ren, Nan Wang, Pengyu Huang, Xiaotong Ma   +10 more
wiley   +1 more source

CoQ10 mitigates BPA-induced cardiotoxicity by maintaining cellular antioxidant levels and Na+/K+-ATPase and Ca2+-ATPase activities

Scientific African
Background: Bisphenol A is an endocrine disruptor widely used by humans, and has diverse toxic effects, such as cardiotoxicity. The cardiotoxic effect of Bisphenol A is multifaceted and includes the depletion of cellular antioxidants and impairment of Na+
W.A. Saka, A.A. Oladipo, C.A. Adegbola, O.E. Adelowo, P.A. Oyedokun, O.R. Kolawole, M.T. Owoeye, T.M. Akhigbe, A.Y. Onaolapo, R.E. Akhigbe   +9 more
doaj   +1 more source

Coenzyme-Q10 és obesitas kapcsolata

, 2016
Az obesitas napjaink egyik legnagyobb problémáját jelentő betegsége, mely egyre több embert érint. Napjainkig is rendkívül nehéz feladat az obesitas és kísérő betegségeinek kezelése, ezért folyamatos kutatasok folynak a lehetséges kiváltó okok, illetve ...
Kádár, Emese Lenke
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