Results 71 to 80 of about 81,810 (279)

Advanced Oral Delivery Systems for Nutraceuticals

Advanced Healthcare Materials, EarlyView.
Emerging delivery technologies are explored to overcome barriers to oral nutraceutical absorption. Traditional carriers are compared with novel platforms including biodegradable polymers, MOFs, MPNs, and 3D printing. These systems enhance bioavailability, control release, and enable personalized nutrition.
Xin Yang, Linzixuan Zhang, Zhiling Zheng, Robert Langer, Ana Jaklenec   +4 more
wiley   +1 more source

Improved Mitochondrial Metabolism and Reduced Inflammation Following Attenuation of Murine Lupus With Coenzyme Q10 Analog Idebenone

Arthritis & Rheumatology, 2020
A role for mitochondrial dysfunction has been proposed in the immune dysregulation and organ damage characteristic of systemic lupus erythematosus (SLE). Idebenone is a coenzyme Q10 synthetic quinone analog and an antioxidant that has been used in humans
L. Blanco, H. Pedersen, Xinghao Wang, Yaima Lightfoot, N. Seto, C. Carmona-Rivera, Zu-Xi Yu, V. Hoffmann, P. S. Yuen, M. Kaplan   +9 more
semanticscholar   +1 more source

EETs Reduction Contributes to Granulosa Cell Senescence and Endometriosis‐Associated Infertility via the PI3K/AKT/mTOR Signaling Pathway

Advanced Science, EarlyView.
1) 14, 15‐EET levels were decreased in ovarian granulosa cells, follicular fluid, peritoneal fluid from endometriosis patients. 2) EETs reduction in endometriosis follicular fluid aggravated granulosa cell senescence. 3) ROS reduced 14, 15‐EET levels by upregulating EPHX2 through a mechanism involving histone methylation modification.
Xiang Lin, Weijia Gu, Xiaomei Tong, Mengru Lai, Yi Zhang, Na Liu, Xiaoying Jin, Chao Li, Dong Huang, Feng Zhou, Yongdong Dai, Songying Zhang   +11 more
wiley   +1 more source

Intrastriatal administration of coenzyme Q10 enhances neuroprotection in a Parkinson’s disease rat model

Scientific Reports, 2020
Parkinson’s disease is a neurodegenerative disorder, and no treatment has been yet established to prevent disease progression. Coenzyme Q10, an antioxidant, has been considered a promising neuroprotective agent; however, conventional oral administration ...
H. Park, Chun Gwon Park, Min Park, Seung Ho Lee, H. Park, Jaesung Lim, S. Paek, Y. B. Choy   +7 more
semanticscholar   +1 more source

Decoupling Electron and Proton Transfer in Noncontact Catalytic Hydrogenation of Nitroaromatics

Advanced Science, EarlyView.
A noncontact catalytic system is constructed by modifying metal nanoparticles supported on conductive carbon with (hypo)phosphorous acid. This design effectively prevents the adsorption of unsaturated substrates while permitting H2 activation to generate electrons and protons. The hydrogenation is governed by electron transfer processes, which occur at
Zhongyin Liang, Qingyuan Wu, Zhe Yang, Nanfeng Zheng   +3 more
wiley   +1 more source

Coenzyme Q10: Novel Formulations and Medical Trends

International Journal of Molecular Sciences, 2020
The aim of this review is to shed light over the most recent advances in Coenzyme Q10 (CoQ10) applications as well as to provide detailed information about the functions of this versatile molecule, which have proven to be of great interest in the medical
Carmen J Pastor-Maldonado, J. M. Suárez-Rivero, Suleva Povea-Cabello, Mónica Álvarez-Córdoba, Irene Villalón-García, Manuel Munuera-Cabeza, Alejandra Suárez-Carrillo, Marta Talaverón-Rey, J. Sánchez-Alcázar   +8 more
semanticscholar   +1 more source

Synthesis of Coenzyme Q10 [PDF]

American Journal of Infectious Diseases, 2009
Problem statement: CoQ10 is a key compound in ATP synthesis having wide number of health application especially for treating humans suffering from pathophysiological condition. The CoQ10 presently available in the market is solely derived from fermentation process. A commercially viable synthetic process is yet to be realized.
Machi Raju Garaga, Suryachandra Rao Ravada, Lakshma Reddy Emani, Trimurtulu Golakoti, Bharani Meka   +4 more
openaire   +2 more sources

Efficacy and Engagement With an Immersive Virtual Learning Experience of the Citric Acid Cycle

Biochemistry and Molecular Biology Education, EarlyView.
ABSTRACT This randomized controlled trial assessed the comparative effectiveness of a biochemistry education program delivered through an immersive virtual reality (iVR) experience and traditional video‐based instruction. Undergraduate students enrolled in three nutrition courses from a large R1 American university participated (n = 95).
Bianca C. Braga, William Hurst, John Barrow, John Long, Gregory C. Shearer, Joanna K. Hodges, Olivia Lawler, Ravi Patel, Terry Schiavone, Travis D. Masterson   +9 more
wiley   +1 more source

The Promise and Pitfalls of Artificial Intelligence in the Evaluation of Synthetic “Greenness”

ChemSusChem, EarlyView.
Rapid rise of AI prompts a question whether it can be used to accelerate and standardize assessment of synthetic “greenness.” This perspective argues for the potential of such applications, although it also identifies several hurdles, like the need for extensive training or the creation of “ground truth” datasets.
Paweł Mateusz Nowak, Michał Woźniakiewicz, Grzegorz J. Nalepa, Bartosz A. Grzybowski   +3 more
wiley   +1 more source

The antioxidant status of coenzyme Q10 and vitamin E in children with type 1 diabetes

Jornal de Pediatria, 2019
Objective: The purpose of this study was to evaluate the antioxidant status of plasma vitamin E and plasma and intracellular coenzyme Q10 in children with type 1 diabetes.
Usama M. Alkholy, Nermin Abdalmonem, Ahmed Zaki, Mohamed A. Elkoumi, Mustafa I. Abu Hashim, Maha A.A. Basset, Hossam E. Salah   +6 more
doaj   +3 more sources