Results 71 to 80 of about 34,301 (245)
Coenzyme Q10 as a therapeutic candidate for treating inherited photoreceptor degeneration [PDF]
, 2017 Inherited photoreceptor degeneration (IPD): The human retina is a highly specialised tissue that enables the perception of light across a range of intensities and colours.
Biswas, Lincoln +5 more
core +4 more sources
European Journal of Heart Failure, EarlyView.Improving clinical translation of mitoprotective therapies. 31P MRI, phosphorus‐31 magnetic resonance imaging; hiPSC‐CM, human‐induced pluripotent stem cell‐derived cardiomyocyte; IHD, ischaemic heart disease. Abstract Acute myocardial infarction (MI) remains a major cause of death and disability worldwide.
Melanie Paillard +29 more
wiley +1 more source
ProtTrans: Towards Cracking the Language of Life's Code Through Self-Supervised Deep Learning and High Performance Computing [PDF]
arXiv, 2020 Computational biology and bioinformatics provide vast data gold-mines from protein sequences, ideal for Language Models taken from NLP. These LMs reach for new prediction frontiers at low inference costs. Here, we trained two auto-regressive models (Transformer-XL, XLNet) and four auto-encoder models (BERT, Albert, Electra, T5) on data from UniRef and ...
arxiv
E3S Web of Conferences, 2018 Contaminated water often affects the occurrence of periodontitis in the coastal area. The diabetic hypercholesterolemia-induced periodontitis in Indonesia is very high.
Saryono Saryono +3 more
doaj +1 more source
Antioxidant Supplementation in the Treatment of Aging-Associated Diseases [PDF]
, 2016 Oxidative stress is generally considered as the consequence of an imbalance between pro- and antioxidants species, which often results into indiscriminate and global damage at the organismal level.
Conti, V +7 more
core +2 more sources
European Journal of Heart Failure, EarlyView.Abstract A better understanding of additional mechanisms of heart failure (HF) progression may allow a different and more complete phenotyping of the disease and identification of novel therapeutic targets. Persistent latent myocardial inflammation/immune activation in HF may represent an attempt to restore tissue homeostasis in the failing heart ...
Gabriele Fragasso +20 more
wiley +1 more source
Development of Carbon-Fiber Electrodes Modified for Electrochemical ATP Detection [PDF]
arXiv, 2018 Adenosine triphosphate (ATP) is a highly energetic molecule used as a coenzyme in the transfer of chemical energy required for the continuation of cellular metabolism. In addition, extracellular ATP has an important role in cell-to-cell communication in immune, nervous and vascular systems.
arxiv
Inherited metabolic epilepsies–established diseases, new approaches
Epilepsia Open, EarlyView.Abstract Inherited metabolic epilepsies (IMEs) represent the inherited metabolic disorders (IMDs) in which epilepsy is a prevailing component, often determining other neurodevelopmental outcomes associated with the disorder. The different metabolic pathways affected by individual IMEs are the basis of their rarity and heterogeneity.
Itay Tokatly Latzer, Phillip L. Pearl
wiley +1 more source
EFFECTIVITY AND PHYSICOCHEMICAL STABILITY OF NANOSTRUCTURED LIPID CARRIER COENZYME Q10 IN DIFFERENT RATIO of LIPID ALFA CETYL PALMITATE AND ALPHA TOCOPHERYL ACETATE AS CARRIER [PDF]
, 2017 Objective: The aim of this study was to investigate physical characteristics of nanostructured lipid carriers (NLCs) mixture of alpha tocopheryl acetate, cetyl palmitate, Tween 80 and propylene glycol using high shear homogenization technique on NLC ...
Hendradi, Esti +2 more
core +1 more source
Food Chemistry International, EarlyView.After adaptive laboratory evolution against nisin, improved nisin production and tolerance were found in the evolved strains. To reveal the advantages of the evolved strains, a systematic comparison was made between the starting strains and the domesticated strains in terms of their microscopic morphology, metabolomics, transcriptomics, and whole ...
Xinyue Liu +7 more
wiley +1 more source