Results 81 to 90 of about 80,404 (288)

Determination of quantum yield of NADH and FAD in alcohol-water solutions: the analysis of radiative and nonradiative relaxation pathways [PDF]

arXiv, 2022
Combined studies on fluorescence quantum yield in coenzymes NADH and FAD in water-methanol, water-ethanol and water-propylene glycol mixtures and on time-resolved fluorescence of the same molecules under excitation at 450 and 355~nm by means of the TCSPC method have been carried out.
arxiv  

Prenatal Brain Abnormalities in Sodium‐Dependent Multivitamin Transporter Deficiency

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT In treatable neurometabolic disorders, early diagnosis and prompt initiation of treatment are key to improved survival and outcomes. Biallelic variants in SLC5A6 cause sodium‐dependent multivitamin transporter deficiency (OMIM # 618973), which is treatable with high‐dose pantothenic acid, biotin, and alpha lipoic acid.
Eri Ogawa, Kenjiro Kosaki, Toshiki Takenouchi   +2 more
wiley   +1 more source

The effect of temperature on basal metabolism of Mnemiopsis leidyi [PDF]

arXiv, 2020
To evaluate the influence of temperature on metabolic performance on the invasive ctenophore Mnemiopsis leidyi, we exposed fully acclimatized adults to conditions typical for the annual variability of the Western Baltic Sea region. We derived basal metabolic rates from oxygen consumption rates of adult M.
arxiv  

The Paradox of Coenzyme Q10 in Aging [PDF]

Nutrients, 2019
Coenzyme Q (CoQ) is an essential endogenously synthesized molecule that links different metabolic pathways to mitochondrial energy production thanks to its location in the mitochondrial inner membrane and its redox capacity, which also provide it with the capability to work as an antioxidant.
M Elena Díaz-Casado, José L. Quiles, Alfonso Varela-López, Eliana Barriocanal-Casado, Luis C. López, Maurizio Battino, Maurizio Battino, Maurizio Battino, Pilar González-García   +8 more
openaire   +4 more sources

Targeting signaling pathways in neurodegenerative diseases: Quercetin's cellular and molecular mechanisms for neuroprotection

Animal Models and Experimental Medicine, EarlyView.
Quercetin regulates signaling pathways in neurodegenerative diseases, including NF‐κB, sirtuins, and PI3K/Akt. Studies show quercetin improves symptoms and pathology in neurodegenerative models. The study aims to incorporate laboratory research into practical medical treatment, focusing on quercetin's neuroprotective effects and optimal dosage ...
Md. Rezaul Islam, Md. Ibrahim Khalil Al‐Imran, Mehrukh Zehravi, Sherouk Hussein Sweilam, Mohammad Rakib Mortuza, Jeetendra Kumar Gupta, Thukani Sathanantham Shanmugarajan, Kadirvel Devi, Tanuja Tummala, Mohammed Ali Alshehri, Kalirajan Rajagopal, Mohammed Asiri, Irfan Ahmad, Talha Bin Emran   +13 more
wiley   +1 more source

Comparative Bioavailability of Different Coenzyme Q10 Formulations in Healthy Elderly Individuals

Nutrients, 2020
Coenzyme Q10 (CoQ10) plays a central role in mitochondrial oxidative phosphorylation. Several studies have shown the beneficial effects of dietary CoQ10 supplementation, particularly in relation to cardiovascular health.
I. Pravst, Juan Carlos Rodríguez Aguilera, Ana Belen Cortes Rodriguez, Janja Jazbar, I. Locatelli, H. Hristov, Katja Žmitek   +6 more
semanticscholar   +1 more source

Induction of Cell Death by Combined Treatment with Photosensitizer‐Chitosan Nanoparticles and the Ferroptosis Inducer RSL3 in Breast Cancer Cell Lines

Advanced NanoBiomed Research, EarlyView.
This study demonstrates that combination of phosphosensitizer‐conjugated chitosan nanoparticles and ferroptosis inducer RSL3 increases cell death in mesenchymal breast cancer cells. Data suggests that this is attributed to variations in ferroptosis‐related protein expression, lipid peroxydation and mitochondrial function.
Marek Feith, Saikat Das Sajib, Anne Grethe Myrann, Anders Høgset, Pablo Garrido, Alfredo Martinez, Erik Knutsen, Kirsten Sandvig, Tore Skotland, Gunhild Mari Mælandsmo, Tore‐Geir Iversen   +10 more
wiley   +1 more source

An Evaluation of the Protective Effects of Coenzyme Q10 on Fertility Parameters of Male Mice Treated with Methotrexate [PDF]

Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul, 2023
Background and Objective: Methotrexate (MTX) is a chemotherapy drug that has destructive effects on body tissues, including the male reproductive system.
M Babaei, A Kalantari-Hesari, M Yavari, M Hallaj, H Morovvati   +4 more
doaj  

Ultrafast polarization-modulation transient spectroscopy to study electronic excited state dynamics in solutions and cells [PDF]

arXiv, 2020
A novel polarization-modulation transient method has been developed for studying fast anisotropic relaxation in electronic excited states of polyatomic and biologically relevant molecules under excitation with femtosecond laser pulses. The method is based on the modulation of pump beam polarization with a photo-elastic modulator and detection of an ...
arxiv  

Topical Delivery of Coenzyme Q10-Loaded Microemulsion for Skin Regeneration

Pharmaceutics, 2020
The aim of this study was to develop a coenzyme Q10 (CoQ10) microemulsion system with improved solubility, penetration, and wound healing efficacy. Based on the pseudo-ternary diagram, microemulsions containing isopropyl myristate (IPM), Cremophor EL ...
Kyeong-A Ryu, P. Park, Seong-Bo Kim, Bum-Ho Bin, Dong-Jin Jang, Sung Tae Kim   +5 more
semanticscholar   +1 more source