Neuronal cells depend on mitochondrial oxidative phosphorylation for most of their energy needs and therefore are at a particular risk for oxidative stress.
M. Somayajulu+5 more
doaj
Cardiorenal Involvement in Metabolic Syndrome Induced by Cola Drinking in Rats: Proinflammatory Cytokines and Impaired Antioxidative Protection [PDF]
We report experimental evidence confirming renal histopathology, proinflammatory mediators, and oxidative metabolism induced by cola drinking. Male Wistar rats drank ad libitum regular cola (C, = 12) or tap water (W, = 12). Measures.
Ambrosio, Giuseppe+7 more
core +1 more source
Dry Eye Disease: Oxidative Stress on Ocular Surface and Cutting‐Edge Antioxidants
This review has systematically evaluated the oxidative damage of cornea, tear film, lacrimal gland, conjunctiva and meibomian gland for dry eye, and concluded the antioxidants that are either commercially available or in the research phase. GQDs: Graphene quantum dots; LF: lactoferrin; ROS: Reactive oxygen species; SOD: Superoxide dismutase; tFNA ...
Rong Hu+3 more
wiley +1 more source
Electron spin and the origin of Bio-homochirality I. Extant enzymatic reaction model [PDF]
In this paper, I tentatively put forward a new hypothesis that the emergence of a single chiral form of biomolecules in living organisms is specifically determined by the electron spin state during their enzyme-catalyzed synthesis processes. Specifically speaking, the electrons released from the coenzyme NAD(P)H of amino acid synthase are heterogeneous
arxiv
The role of Coenzyme Q10 in statin-associated myopathy [PDF]
Statins, or 3-hydroxyl-3-methylglutaryl coenzyme HMG-CoA reductase inhibitors,\ud are cholesterol-lowering drugs which are frequently used in the primary and secondary\ud prevention of coronary artery disease. Current research and recommendations support\
Kalra, Dr Sanjay
core
Mitochondrial dysfunction: Related diseases, influencing factors, and detection
Mitochondrial dysfunction is implicated in the pathogenesis of numerous diseases, including neurological disorders, cancers, and cardiovascular conditions, through mechanisms such as mitochondrial DNA mutations, dysregulation of mitochondrial network dynamics, and impaired mitophagy.
Zhaojin Li+9 more
wiley +1 more source
THE MODERN METHODS OF ANALYSIS OF OXIDIZED AND REDUCED FORMS OF COENZYME Q₁₀ IN BIOMATERIAL (REVIEW)
In the human body, coenzyme Q10 is in the oxidized and reduced forms and can be found in every organ. The review describes modern HPLC methods of coenzyme Q10 analysis using electrochemical, spectrophotometric and mass spectrometric detectors.
V. I. Zozina+3 more
doaj
Atorvastatin therapy and antioxidant status correction in patients with metabolic syndrome
Aim. To study the changes in antioxidant status and glucose-insulin homeostasis among atorvastatin-treated patients with metabolic syndrome and to investigate the potential of coenzyme Q10 for the correction of these changes. Material and methods.
N. S. Yubitskaya+2 more
doaj +1 more source
Effect of metabolic and antioxidant supplementation on sperm parameters in oligo-astheno-teratozoospermia, with and without varicocele: a double-blind placebo-controlled study [PDF]
Since sperm require high energy levels to perform their specialised function, it is vital that essential nutrients are available for spermatozoa when they develop, capacitate and acquire motility.
Agarwal, A.+8 more
core +1 more source
Regional outbreak of parvovirus B19 acute myocarditis in preschool children
We recently came across an outbreak of parvovirus B19 related acute myocarditis in preschool children in a specific region in northern Greece. The children exhibited serious morbidity and mortality. All children had very poor left ventricular ejection fraction and required inotropic intensive care unit support.
Filippos‐Paschalis Rorris+3 more
wiley +1 more source