Physiological metabolic analysis and process optimization of hypoxia in promoting coenzyme Q<sub>10</sub> biosynthesis and accumulation in <i>Rhodobacter sphaeroides</i> HY01. [PDF]
Li B +9 more
europepmc +1 more source
Oxidative Stress and DNA Epigenetic Modifications in Cancer: Mechanisms and Targeted Therapeutics
Reactive oxygen species (ROS) modulate DNA methyltransferases (DNMTs), ten‐eleven translocation family proteins (TETs) and their cofactors, reshaping 5‐methylcytosine (5mC)/5‐hydroxymethylcytosine (5hmC)/5‐formylcytosine (5fC) landscapes and gene expression in cancer cells. In turn, epigenetic control of antioxidant and metabolic pathways feeds back on
Xishan Yang +7 more
wiley +1 more source
Spatial mapping of CoQ10 repletion by BPM31510 in a genetic mouse model (Coq4<sup>F147C</sup>) of coenzyme Q deficiency. [PDF]
Barriocanal-Casado E +15 more
europepmc +1 more source
Proteolytic control of mitochondrial protein translocases. [PDF]
Abstract Mitochondria are essential organelles that drive numerous cellular processes, including energy metabolism, ion homeostasis, and programmed cell death. This functional versatility relies on a highly dynamic proteome whose composition is continuously remodeled to meet changing cellular and environmental demands.
Kroczek L, Langer T.
europepmc +2 more sources
Oxidative Stress in the Tumor Immune Microenvironment: Mechanisms and Therapeutic Perspectives
Oxidative stress is involved in several key processes in cancer, including redox regulation, DNA damage, post‐translational modifications, transcriptional regulation, epigenetic modifications, metabolic reprogramming, cell death, and immune modulation. These mechanisms collectively influence tumor progression, immune evasion, and therapeutic responses,
Zhen Wang +14 more
wiley +1 more source
Comment on "Phase I Randomized, Placebo-Controlled, Cross-Over Dose-Finding Study of Coenzyme Q<sub>10</sub> on Doxorubicin Pharmacokinetics During Breast Cancer Treatment". [PDF]
Lei Z.
europepmc +1 more source
Effects of lipid-lowering drugs on epilepsy and its subtypes: A drug-target Mendelian randomization study. [PDF]
Wang Y, Huang S.
europepmc +1 more source
Enhancement of antibody production by the addition of Coenzyme-Q(10). [PDF]
Konno Y +6 more
europepmc +1 more source

