Results 211 to 220 of about 103,462 (335)

Therapeutic Effects of Coenzyme Q₁₀and Remacemide in Transgenic Mouse Models of Huntington's Disease [PDF]

, 2002
Robert J. Ferrante, Ole A. Andreassen, Alpaslan Dedeoglu, Kimberly L. Ferrante, Bruce G. Jenkins, Steven M. Hersch, M. Flint Beal   +6 more
openalex   +1 more source

Inhibition of Histone Lysine Acetyltransferases by Coenzyme A Analogs. [PDF]

Molecules
Voukia F, Bilgin N, Andersen SB, Mecinović J.   +3 more
europepmc   +1 more source

Simvastatin Restores Uteroplacental Hemodynamics and Trophoblast Function in Obstetric Antiphospholipid Syndrome in a Placenta‐on‐a‐Chip Model

Advanced Healthcare Materials, Volume 15, Issue 18, 15 May 2026.
Simvastatin mitigates placental hypoperfusion in OAPS by ameliorating abnormal uteromaternal hemodynamics and enhancing trophoblast invasion via optimized endothelial cell interactions under pathological shear stress, as evidenced by results from a placenta‐on‐a‐chip platform.
Hongli Liu, Yuan Wang, Yanjun Cai, Ruixin Guo, Shunhua Liu, Tingting Chen, Tingting Sun, Ruiheng Huo, Tengwei Liu, Qingfeng Lv, Xietong Wang   +10 more
wiley   +1 more source

MVP Inhibits Influenza A Virus‐Induced Ferroptosis by Targeting IRF1 and Increasing FSP1 Activity

Advanced Science, Volume 13, Issue 26, 8 May 2026.
During IAV infection, MVP inhibits IRF1 polyubiquitination, thereby relieving IRF1‐mediated transcriptional inhibition of FSP1. Consequently, this leads to an upregulation of FSP1 expression, thereby reinforcing the inhibition of ferroptosis. In addition, the MVP can promote myristoylation and ubiquitination of FSP1, enabling its membrane localization ...
Yingbo Chen, Paili Lin, Yongfang Xia, Zhiqiang Liu, Zilu Cheng, Qingmei Zhu, Shiqi Wan, Xiaoyu Chen, Haiyan Bao, Renbo Qiao, Gechang Zhong, Ying Zhu, Shi Liu   +12 more
wiley   +1 more source

The Age‐Dependent Resident Myonuclear Multi‐Omic Response to an Acute Skeletal Muscle Hypertrophic Stimulus in Mice

Advanced Science, Volume 13, Issue 25, 4 May 2026.
Resident myonuclei are the molecular “control centers” for large multinuclear muscle fibers. It is presumed that, with aging, these control centers become compromised and contribute to delayed or blunted muscle adaptive potential. This study is a detailed roadmap that exposes how young versus aged myonuclei respond to a hypertrophic loading stimulus ...
Pieter J. Koopmans, Ronald G. Jones III, Ana Regina Cabrera, Francielly Morena, Nicholas P. Greene, John J. McCarthy, Ahmed Ismaeel, Yuan Wen, Kevin A. Murach   +8 more
wiley   +1 more source

SIRT1 Prevents Ferroptosis in Corneal Epithelial Cells by Enhancing HIF1α Protein Stability in Dry Eye Disease

Advanced Science, Volume 13, Issue 26, 8 May 2026.
Hyperosmotic stress drives ferroptosis in corneal epithelium via SIRT1 downregulation. This work demonstrates that SIRT1 activation stabilizes HIF1α, which transcriptionally upregulates GPX4 to inhibit lipid peroxidation and cell death. The identified SIRT1/HIF1α/GPX4 axis reveals a novel defense mechanism and potential therapy for dry eye disease ...
Lili Lian, Zhenmin Le, Xuanqiao Ye, Zimo Wang, Jiuxiao Li, Chenyu Dong, Yetao Shen, Jiazheng Li, Yueping Ren, Xiaoyin Ma, Wei Chen, Qinxiang Zheng   +11 more
wiley   +1 more source

Impact of liposomal delivery on coenzyme Q10 absorption: a double-blind, placebo-controlled, randomized trial. [PDF]

Front Nutr
Jäger R, Purpura M, Godavarthi A, Ceylan HI, Balcombe ST, Chandrappa A, Tinsley GM.   +6 more
europepmc   +1 more source

Efficient production of coenzyme Q₁₀ from acid hydrolysate of sweet sorghum juice by Rhodobacter sphaeroides

, 2019
Yong Wang, S. Chen, J. Liu, Pengmei Lv, Di Cai, Guanglei Zhao   +5 more
openalex   +2 more sources

Central Dogma Cycle and Network: A Model for Cell Memory

BioEssays, Volume 48, Issue 5, May 2026.
This paper revisits the Central Dogma, expanding it to the Central Dogma cycle (CDC) and Central Dogma cyclic network (CDCN). These models frame cellular memory as a system of logic‐based processes with an architecture of interconnected cycles that more accurately describe cellular information flow in cells. ABSTRACT This paper proposes an extension of
Martin R. Schiller
wiley   +1 more source

Crystal structure of a short-chain dehydrogenase from Brucella ovis with apo and coenzyme NAD⁺-bound protomer chains. [PDF]

Acta Crystallogr F Struct Biol Commun
Zupko SP, Konstanty AT, Mayclin SJ, Choi R, Serbzhinskiy D, Robles E, Moses V, Barrett LK, Van Voorhis WC, Edwards TE, Myler PJ, Torelli AT, French JB, Hicks KA.   +13 more
europepmc   +1 more source