Results 31 to 40 of about 102,445 (274)

ZZE-Configuration of chromophore ß-153 in C-phycocyanin from Mastigocladus laminosus [PDF]

, 1987
The photochemistry of C-phycocyanin has been studied after denaturation in the dark. It shows an irreversible reaction which has characteristics of a Ζ,Ζ,Ε- to Z,Z,Z-isomerization of dihydrobilins. Its amplitude depends on the reaction conditions, with
Bode, W., Fischer, R., Huber, R., Rüdiger, W., Scheer, Hugo, Schirmer, T., Schmidt, G., Siebzehnrübl, S.   +7 more
core   +1 more source

Antioxidative stress-induced damage in cochlear explants

Journal of Otology, 2020
The imbalance of reactive oxygen species and antioxidants is considered to be an important factor in the cellular injury of the inner ear. At present, great attention has been placed on oxidative stress.
Dalian Ding, Jianghui Zhang, Fang Liu, Peng Li, Weidong Qi, Yazhi Xing, Haibo Shi, Haiyan Jiang, Hong Sun, Shankai Yin, Richard Salvi   +10 more
doaj   +1 more source

Traumatic Brain Injury Alters Cerebral Concentrations and Redox States of Coenzymes Q₉ and Q₁₀ in the Rat

Antioxidants, 2023
To date, there is no information on the effect of TBI on the changes in brain CoQ levels and possible variations in its redox state. In this study, we induced graded TBIs (mild TBI, mTBI and severe TBI, sTBI) in male rats, using the weight-drop closed ...
Giacomo Lazzarino, Renata Mangione, Miriam Wissam Saab, Barbara Tavazzi, Alessandra Pittalà, Stefano Signoretti, Valentina Di Pietro, Giuseppe Lazzarino, Angela Maria Amorini   +8 more
doaj   +1 more source

Effects of an Intervention with Selenium and Coenzyme Q₁₀ on Five Selected Age-Related Biomarkers in Elderly Swedes Low in Selenium: Results That Point to an Anti-Ageing Effect—A Sub-Analysis of a Previous Prospective Double-Blind Placebo-Controlled Randomised Clinical Trial

Cells, 2023
Background: Ageing is associated with cardiovascular disease (CVD). As no single biomarker reflects the full ageing process, we aimed to investigate five CVD- and age-related markers and the effects of selenium and coenzyme Q10 intervention to elucidate ...
Urban Alehagen, Jan Alexander, Jan O. Aaseth, Anders Larsson, Erland Svensson, Trine B. Opstad   +5 more
doaj   +1 more source

Coenzyme Q(10) Therapy

, 2023
For a number of years, coenzyme Q 10 (CoQ 10 ) was known for its key role in mitochondrial bioenergetics; later studies demonstrated its presence in other subcellular fractions and in blood plasma, and extensively investigated its antioxidant role. These 2 functions constitute the basis for supporting the clinical use of CoQ 10 .
Garrido-Maraver, Juan, Cordero, Mario D., Oropesa-Ávila, Manuel, Fernández Vega, Alejandro, Mata, Mario de la, Delgado Pavón, Ana, Miguel Rodríguez, Manuel de, Sánchez-Alcázar, José Antonio   +7 more
openaire   +2 more sources

Antioxidant Supplementation in the Treatment of Aging-Associated Diseases [PDF]

, 2016
Oxidative stress is generally considered as the consequence of an imbalance between pro- and antioxidants species, which often results into indiscriminate and global damage at the organismal level.
Conti, V, Corbi, G, De Lise, F, Di Donato, A, Filippelli, A, Izzo, V, Manzo, V, Russomanno, G   +7 more
core   +2 more sources

The Important Role of CoQ₁₀ in Aging

Antioxidants, 2019
Coenzyme Q10 (CoQ10) is an essential lipid present in all cell membranes[...]
Guillermo López-Lluch
doaj   +1 more source

Increased SIRT1 Concentration Following Four Years of Selenium and Q₁₀ Intervention Associated with Reduced Cardiovascular Mortality at 10-Year Follow-Up—Sub-Study of a Previous Prospective Double-Blind Placebo-Controlled Randomized Clinical Trial

Antioxidants, 2023
Background: Selenium and coenzyme Q10 (SeQ10) possess antioxidant and anti-inflammatory properties, potentially mediated via Sirtuin1 (SIRT1). We aimed to investigate the influence of a SeQ10 intervention on SIRT1 concentration, with potential ...
Trine Baur Opstad, Jan Alexander, Jan Aaseth, Anders Larsson, Ingebjørg Seljeflot, Urban Alehagen   +5 more
doaj   +1 more source

Atherosclerosis and Coenzyme Q10 [PDF]

International Journal of Molecular Sciences, 2019
Atherosclerosis is the most common cause of cardiac deaths worldwide. Classically, atherosclerosis has been explained as a simple arterial lipid deposition with concomitant loss of vascular elasticity. Eventually, this condition can lead to consequent blood flow reduction through the affected vessel.
Juan M. Suárez-Rivero, Carmen J. Pastor-Maldonado, Mario de la Mata, Marina Villanueva-Paz, Suleva Povea-Cabello, Mónica Álvarez-Córdoba, Irene Villalón-García, Alejandra Suárez-Carrillo, Marta Talaverón-Rey, Manuel Munuera, José A. Sánchez-Alcázar   +10 more
openaire   +3 more sources

Remnants of an ancient metabolism without phosphate [PDF]

, 2017
Phosphate is essential for all living systems, serving as a building block of genetic and metabolic machinery. However, it is unclear how phosphate could have assumed these central roles on primordial Earth, given its poor geochemical accessibility.
Goldford, Joshua E., Hartman, Hyman, Segrè, Daniel, Smith, Temple F.   +3 more
core   +1 more source