Results 1 to 10 of about 32,845 (292)

Coenzyme-protein interactions since early life [PDF]

eLife
Recent findings in protein evolution and peptide prebiotic plausibility have been setting the stage for reconsidering the role of peptides in the early stages of life’s origin.
Alma Carolina Sanchez Rocha, Mikhail Makarov, Lukáš Pravda, Marian Novotný, Klára Hlouchová   +4 more
doaj   +2 more sources

Vitamin D(3) and methylenebisphosphonic acid in the correction of mineral metabolism disorders and bone remodeling associated with glucocorticoid-induced osteoporosis [PDF]

The Ukrainian Biochemical Journal, 2023
The study was aimed at evaluating therapeutic efficacy of vitamin D3 (VD3, 1000 IU/kg of b.w., 30 days) and sodium salt of methylenebisphosphonic acid (MBPA, 17 mg/kg of b.w., 30 days) monotherapies as well as their effect in combination in preventing ...
O. O. Lisakovska, I. O. Shymanskyi, V. M. Vasylevska, E. P. Pasichna, M. M. Veliky, S. V. Komisarenko   +5 more
doaj   +1 more source

Brain vitamin D3-auto/paracrine system in relation to structural, neurophysiological, and behavioral disturbances associated with glucocorticoid-induced neurotoxicity

Frontiers in Cellular Neuroscience, 2023
IntroductionVitamin D3 (VD3) is a potent para/autocrine regulator and neurosteroid that can strongly influence nerve cell function and counteract the negative effects of glucocorticoid (GC) therapy.
Olha Lisakovska, Dmytro Labudzynskyi, Anna Khomenko, Dmytro Isaev, Alina Savotchenko, Ludmila Kasatkina, Serhii Savosko, Mykola Veliky, Ihor Shymanskyi   +8 more
doaj   +1 more source

Indirect Export of Reducing Equivalents From the Chloroplast to Resupply NADP for C3 Photosynthesis—Growing Importance for Stromal NAD(H)?

Frontiers in Plant Science, 2021
Plant productivity greatly relies on a flawless concerted function of the two photosystems (PS) in the chloroplast thylakoid membrane. While damage to PSII can be rapidly resolved, PSI repair is complex and time-consuming. A major threat to PSI integrity
Moritz Krämer, Hans-Henning Kunz
doaj   +1 more source

Effect of Propionic Acid on Diabetes-Induced Impairment of Unfolded Protein Response Signaling and Astrocyte/Microglia Crosstalk in Rat Ventromedial Nucleus of the Hypothalamus

Neural Plasticity, 2022
Background. The aim was to investigate the influence of propionic acid (PA) on the endoplasmic reticulum (ER), unfolded protein response (UPR) state, and astrocyte/microglia markers in rat ventromedial hypothalamus (VMH) after type 2 diabetes mellitus ...
Larysa V. Natrus, Yulia S. Osadchuk, Olha O. Lisakovska, Dmytro O. Labudzinskyi, Yulia G. Klys, Yuri B. Chaikovsky   +5 more
doaj   +1 more source

The contribution of the Nobel prize laureates to the development of knowledge of vitamin biochemistry: Ch. Eijkman, F. G. Hopkins, A. Szent-Györgyi, W. Haworth, P. Karrer, R. Kuhn, H. Dam, E. A. Doisy, G. Minot, W. Murphy, G. Whipple, D. Hodgkin, R. Woodward [PDF]

The Ukrainian Biochemical Journal, 2019
In the first half of the 20th century, the experimental research of chemists, biochemists and physiologists in collaboration with doctors led to the discovery of a new class of biologically active compounds – vitamins.
V. M. Danilova, R. P. Vynogradova, S. V. Komisarenko   +2 more
doaj   +1 more source

Vitamin D Auto-/Paracrine System Is Involved in Modulation of Glucocorticoid-Induced Changes in Angiogenesis/Bone Remodeling Coupling

International Journal of Endocrinology, 2020
Osteoporosis is a devastating side effect of chronic glucocorticoid (GC) treatment. Despite the crucial role of vitamin D (VD) in bone homeostasis, the precise molecular mechanisms of its action on GC-induced disturbances of bone remodeling remain ...
Olha Lisakovska, Ihor Shymanskyi, Dmytro Labudzynskyi, Anna Mazanova, Mykola Veliky   +4 more
doaj   +1 more source

Iron-sulfur flavoenzymes: the added value of making the most ancient redox cofactors and the versatile flavins work together

Open Biology, 2021
Iron-sulfur (Fe-S) flavoproteins form a broad and growing class of complex, multi-domain and often multi-subunit proteins coupling the most ancient cofactors (the Fe-S clusters) and the most versatile coenzymes (the flavin coenzymes, FMN and FAD).
Maria Antonietta Vanoni
doaj   +1 more source

4,7-Dimethoxy-6-propyl-2H-1,3-benzodioxole-5-carbaldehyde

Molbank, 2023
A simple intermediate for the synthesis of methoxy-analogues of coenzymes Q with substituents having various chain lengths based on natural polyalkoxyallylbenzene apiol has been developed.
Dmitry V. Tsyganov, Victor V. Semenov
doaj   +1 more source

Structure and function of yeast alcohol dehydrogenase [PDF]

Journal of the Serbian Chemical Society, 2000
1. Introduction 2. Isoenzymes of YADH 3. Substrate specificity 4. Kinetic mechanism 5. Primary structure 6. The active site 7. Mutations in the yeast enzyme 8. Chemical mechanism 9. Binding of coenzymes 10.
VLADIMIR LESKOVAC, SVETLANA TRIVIC
doaj   +2 more sources