Results 101 to 110 of about 99,240 (382)
Biosynthetic potentials of metabolites and their hierarchical organization [PDF]
Peer reviewedPublisher ...
Ebenhoeh, Oliver+2 more
core +4 more sources
This study develops a human engineered heart tissue‐derived model of diabetic cardiomyopathy that accurately replicates the dynamic changes in the structural, contractile, and electrophysiological properties of the myocardium. Furthermore, this model is used to confirm the direct protective effects of empagliflozin on the heart through an SGLT2 off ...
Lin Cai+9 more
wiley +1 more source
Folic Acid Effect on Arginase Activity in Human Colostrum and Mature Milk
Folic acid, or folates are available from a large variety of sources, such as green leafy vegetables (spinach, beans) and liver. The importance of folates is based on their requirement as coenzymes in the transfer and utilization of one-carbon units in a
Bjelakovic Ljiljana+7 more
doaj +1 more source
Characterisation of FAD-family folds using a machine learning approach [PDF]
Flavin adenine dinucleotide (FAD) and its derivatives play a crucial role in biological processes. They are major organic cofactors and electron carriers in both enzymatic activities and biochemical pathways. We have analysed the relationships between
Gilbert, D, Tan, A C, Tuson, A
core
Autofluorescence of atmospheric bioaerosols – fluorescent biomolecules and potential interferences [PDF]
Primary biological aerosol particles (PBAP) are an important subset of air particulate matter with a substantial contribution to the organic aerosol fraction and potentially strong effects on public health and climate.
C. Pöhlker, J. A. Huffman, U. Pöschl
core +1 more source
Biosynthesis rates of 13 FFAs are quantitatively calculated in 15 tissues from glucose and an analytical framework to quantitatively calculate inter‐tissue communications of fatty acids between the liver and other tissues is developed. Moreover, the approach is extended to aging condition and a system‐wide decline of fatty acid synthesis in peripheral ...
Beizi Xing+4 more
wiley +1 more source
γGC deficiency in ulcerative colitis drives macrophage ferroptosis‐mediated inflammation. Claw‐engaged microparticles armed with γGC (γGC‐MPs) enhance lesion targeting, promoting localized γGC release and tissue uptake. On the cover, Monkey King (Macrophages) was bound by the Immortal‐Binding Rope and subsequently sealed beneath the Five‐Fingered ...
Rong Wang+10 more
wiley +1 more source
One-carbon metabolism is essential to provide activated one-carbon units in the biosynthesis of methionine, purines, and thymidylate. The major forms of folates in vivo are polyglutamylated derivatives.
H. Cherest+2 more
semanticscholar +1 more source
Metal‐Ligand Complexes as Multifunctional Platforms for Photo‐Activated Cancer Therapy
Metal‐ligand complexes serve as multifunctional platforms for photo‐activated cancer therapy, facilitating photothermal and photodynamic effects through light absorption and reactive oxygen species generation. This review categorizes these complexes by ligand and metal types, examines their roles in combined therapeutic approaches, and explores ...
Jeonga Kim, Saehan Choi, Yoonsung Nam
wiley +1 more source
Abstract The following evidence supports the conclusion that the reaction catalyzed by succinyl coenzyme A:3-keto acid coenzyme A transferase proceeds through two half-reactions in a "ping-pong" mechanism with an enzyme-CoA intermediate. (a) Double reciprocal plots of the initial rates against substrate concentration for the reaction in each direction ...
William P. Jencks, Louis B. Hersh
openaire +3 more sources