Results 21 to 30 of about 85,138 (342)
Iso-coenzyme A is an isomer of coenzyme A in which the monophosphate is attached to the 2'-carbon of the ribose ring. Although iso-CoA was first reported in 1959 (Moffatt, J. G., and Khorana, H. G. (1959) J. Am. Chem. Soc. 81, 1265-1265) to be a by-product of the chemical synthesis of CoA, relatively little attention has been focused on iso-CoA or on ...
David E. Bostwick+4 more
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Background. The aim was to investigate the influence of propionic acid (PA) on the endoplasmic reticulum (ER), unfolded protein response (UPR) state, and astrocyte/microglia markers in rat ventromedial hypothalamus (VMH) after type 2 diabetes mellitus ...
Larysa V. Natrus+5 more
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Coenzymes and Their Role in the Evolution of Life
The evolution of coenzymes, or their impact on the origin of life, is fundamental for understanding our own existence. Having established reasonable hypotheses about the emergence of prebiotic chemical building blocks, which were probably created under ...
A. Kirschning
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The contribution of the Nobel prize laureates to the development of knowledge of vitamin biochemistry: Ch. Eijkman, F. G. Hopkins, A. Szent-Györgyi, W. Haworth, P. Karrer, R. Kuhn, H. Dam, E. A. Doisy, G. Minot, W. Murphy, G. Whipple, D. Hodgkin, R. Woodward [PDF]
In the first half of the 20th century, the experimental research of chemists, biochemists and physiologists in collaboration with doctors led to the discovery of a new class of biologically active compounds – vitamins.
V. M. Danilova+2 more
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Iron-sulfur (Fe-S) flavoproteins form a broad and growing class of complex, multi-domain and often multi-subunit proteins coupling the most ancient cofactors (the Fe-S clusters) and the most versatile coenzymes (the flavin coenzymes, FMN and FAD).
Maria Antonietta Vanoni
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4,7-Dimethoxy-6-propyl-2H-1,3-benzodioxole-5-carbaldehyde
A simple intermediate for the synthesis of methoxy-analogues of coenzymes Q with substituents having various chain lengths based on natural polyalkoxyallylbenzene apiol has been developed.
Dmitry V. Tsyganov, Victor V. Semenov
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Structure and function of yeast alcohol dehydrogenase [PDF]
1. Introduction 2. Isoenzymes of YADH 3. Substrate specificity 4. Kinetic mechanism 5. Primary structure 6. The active site 7. Mutations in the yeast enzyme 8. Chemical mechanism 9. Binding of coenzymes 10.
VLADIMIR LESKOVAC, SVETLANA TRIVIC
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Osteoporosis is a devastating side effect of chronic glucocorticoid (GC) treatment. Despite the crucial role of vitamin D (VD) in bone homeostasis, the precise molecular mechanisms of its action on GC-induced disturbances of bone remodeling remain ...
Olha Lisakovska+4 more
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The content of riboflavin and its coenzymes forms in the brain of rats of different ages
The content of total riboflavin and its coenzymes (FAD and FMN) in the brain homogenates of rats of different ages by means of fluorimetric ion exchange chromatography was determined. The experiment included 3 age groups of rats: 3 months, 10-12 months,
N. L. Fedorko+2 more
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The “great” controlling nucleotide coenzymes
Nucleotide coenzymes dot the map of metabolic pathways providing energy to drive the reactions of the pathway and play an important role in regulating and controlling energy metabolism through their shared potential energy, which is widely unobserved due
R. Veech+5 more
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