Results 31 to 40 of about 32,845 (292)

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

open access: yesFEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida   +6 more
wiley   +1 more source

Coenzyme [PDF]

open access: yes, 2008
Citation: 'coenzyme' in the IUPAC Compendium of Chemical Terminology, 3rd ed.; International Union of Pure and Applied Chemistry; 2006. Online version 3.0.1, 2019. 10.1351/goldbook.C01126 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms.
openaire   +2 more sources

Vitamin D3 affects liver expression of pro-/anti-inflammatory cytokines and nitric oxide synthases in type 2 diabetes

open access: yesExperimental Biology and Medicine
Our objective was to study the effect of vitamin D3 (VD) on hepatocellular oxidative-nitrosative stress and pro/anti-inflammatory cytokines in relation to nitric oxide (NO) formation and NO synthase (NOS) levels in type 2 diabetes mellitus (T2DM).
Ihor Shymanskyi   +9 more
doaj   +1 more source

Bio-Inspired Smart Nanoparticles in Enhanced Cancer Theranostics and Targeted Drug Delivery

open access: yesJournal of Functional Biomaterials, 2022
Globally, a significant portion of deaths are caused by cancer.Compared with traditional treatment, nanotechnology offers new therapeutic options for cancer due to its ability to selectively target and control drug release.
Khushabu Gulia   +5 more
doaj   +1 more source

Nano‐ and Micro‐Sized Solid Materials Used as Antiviral Agents

open access: yesAdvanced Functional Materials, EarlyView.
Due to the rise of viral infections in humans and possible viral outbreaks, the use of nano‐ or micro‐sized materials as antiviral agents is rapidly increasing. This review explores their antiviral properties against RNA and DNA viruses, either as a prevention or a treatment tool, by delving into their mechanisms of action and how to properly assess ...
Orfeas‐Evangelos Plastiras   +6 more
wiley   +1 more source

Coenzyme Q10 Deficiency [PDF]

open access: yesDeutsches Ärzteblatt international, 2016
The prevalence of dyslipidemia is high. It is usually treated with statins which inhibit HMG-CoA reductase and also coenzyme Q10 synthesis. This may lead to muscle pain. The question whether coenzyme Q10 replacement treatment helps to improve these muscle symptoms has been evaluated in a prospective study.
openaire   +2 more sources

3D Microprinting of Structures with Lanthanide‐Based Fluorophores on Optical Fibers for Multiplexed Sensing

open access: yesAdvanced Optical Materials, EarlyView.
Incorporating lanthanide‐based fluorophores into commercial resists for femtosecond direct laser writing enables a novel platform for multiplexed sensing. Porous, periodic, and solid luminescent microstructures fabricated directly on optical fiber tips are presented.
Valese Aslani   +8 more
wiley   +1 more source

Nanoemulsion-directed growth of MOFs with versatile architectures for the heterogeneous regeneration of coenzymes

open access: yesNature Communications, 2022
Controlling the structure of hierarchical metal-organic frameworks via soft template remains a challenge. Here, the authors report a salt-assisted nanoemulsion-guided strategy to achieve continuous structure transition of hierarchical Zr-based MOFs.
Ke Li   +3 more
doaj   +1 more source

Metabolic Changes in Maternal and Cord Blood in One Case of Pregnancy-Associated Breast Cancer Seen by Fluorescence Lifetime Imaging Microscopy

open access: yesDiagnostics, 2021
Pregnancy-associated breast cancer (PABC) is a rare disease, which is frequently diagnosed at an advanced stage due to limitations in current diagnostic methods.
Li Zhou   +7 more
doaj   +1 more source

Ratoon Season Rice Reduces Methane Emissions by Limiting Acetic Acid Transport to the Rhizosphere and Inhibiting Methanogens

open access: yesAdvanced Science, EarlyView.
This study finds that the interaction between ABA‐OsCIPK2‐OsSWEET1A reduces the allocation of methane producing bacteria carbon source (acetic acid) content to the rhizosphere soil of ratoon season rice, thereby reducing methane emissions. Abstract Rice paddies are a major, persistent source of atmospheric methane (CH4), emission rates depend on the ...
Jingnan Zou   +14 more
wiley   +1 more source

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