Results 61 to 70 of about 98,142 (384)
Molecular Oncology, EarlyView.Elevated level of cholesterol is positively correlated to prostate cancer development and disease severity. Cholesterol‐lowering drugs, such as statins, are demonstrated to inhibit prostate cancer. VNPP433‐3β interrupts multiple signaling and metabolic pathways, including cholesterol biosynthesis, AR‐mediated transcription of several oncogenes, mRNA 5′
Retheesh S. Thankan +10 more
wiley +1 more source
Ultrafast absorption kinetics of NADH in folded and unfolded conformations [PDF]
, 2013 The non-radiative energy transfer is shown to occur on a ~3ps time scale for NADH in the folded form in H2O.
Groma, G. I. +4 more
core +1 more source
Arthritis Care &Research, EarlyView.Objective Our objective was to examine the relationship between colchicine plasma concentrations and clinical and demographic factors and to determine the relationship between colchicine concentrations and colchicine efficacy and colchicine‐specific adverse events.
Lisa K. Stamp +8 more
wiley +1 more source
A new limit for blood metabolite analysis using 1H NMR spectroscopy
Journal of Magnetic Resonance Open, 2022 Human blood is the most widely used biospecimen in the clinic and the metabolomics field. While both mass spectrometry and NMR spectroscopy are the two premier analytical platforms in the metabolomics field, NMR exhibits several unsurpassed ...
G.A. Nagana Gowda +2 more
doaj
The diverse roles of flavin coenzymes--nature's most versatile thespians.
Journal of Organic Chemistry, 2007 Flavin coenzymes play a variety of roles in biological systems. This Perspective highlights the chemical versatility of flavins by reviewing research on five flavoenzymes that have been studied in our laboratory.
S. Mansoorabadi +2 more
semanticscholar +1 more source
The Regulation of Trace Metal Elements in Cancer Ferroptosis
Advanced Biology, EarlyView.The induction of ferroptosis inhibits tumor growth, enhances anticancer efficacy, and overcomes drug resistance. Recent evidence shows nonferrous metal elements play a role in ferroptosis. This review focuses on how trace metals regulate ferroptosis processes like iron accumulation, lipid peroxidation, and antioxidant defense.
Xiaoyan Wang +5 more
wiley +1 more source
Oxidative Stress: Concept and Some Practical Aspects
Antioxidants, 2020 Oxidative stress is defined as “an imbalance between oxidants and antioxidants in favor of the oxidants, leading to a disruption of redox signaling and control and/or molecular damage”. This Commentary presents basic features of this global concept which
Helmut Sies
doaj +1 more source
Diagnostics, 2021 Pregnancy-associated breast cancer (PABC) is a rare disease, which is frequently diagnosed at an advanced stage due to limitations in current diagnostic methods.
Li Zhou +7 more
doaj +1 more source
A Prebiotic Pathway to Nicotinamide Adenine Dinucleotide [PDF]
Enzymes play a fundamental role in cellular metabolism. A wide range of enzymes require the presence of complementary coenzymes and cofactors to function properly.
Bechtel, Maximilian +2 more
core +1 more source
Advanced Healthcare Materials, Volume 14, Issue 7, March 14, 2025.The top‐performing lipid nanoparticle, incorporating a novel ionizable lipid derived from vitamin B5, demonstrates high mRNA transfection efficiency, low toxicity, favorable stability, targeted delivery to lymphoid tissues, and high immunogenicity, showing promise as a carrier for mRNA vaccines for infectious diseases and cancer.
Soyeon Yoo +11 more
wiley +1 more source