Determinants of Activity Levels in African Americans With Mild Cognitive Impairment. [PDF]
, 2016 Engaging in cognitive, social, and physical activities may prevent cognitive decline. In a sample of older African Americans with mild cognitive impairment (MCI; N=221), we investigated the cross-sectional relationships between activity levels and ...
Casten, PhD, Robin J. +2 more
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Cognition Enhancers in Age-Related Cognitive Decline [PDF]
Drugs & Aging, 1996 A review of recently published studies on the effect of cognition enhancers in non-demented human study participants is presented. The heterogeneity of the therapeutic target, age-associated cognitive decline, can be improved by separately treating groups in whom age-extrinsic factors may underlie cognitive pathology.
Riedel, Wim J., Jolles, Jellemer
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BMJ Open, 2019 Introduction Managing medication regimens is one of the most complex and burdensome tasks performed by older people, and can be prone to errors. People living with dementia may require medication administration assistance from formal and informal ...
Sarah N Hilmer +10 more
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Probable Early-Onset Alzheimer's Disease in an Apolipoprotein E2 Homozygote [PDF]
, 2010 Objective: To describe a case of early-onset Alzheimer's disease (AD) in an apolipoprotein (Apo) epsilon 2/epsilon 2 homozygote. Background: Apo epsilon 2/epsilon 2 is the rarest of the ApoE genotypes, representing only 1.4% of the population.
Belden, Christine +7 more
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Isolated Cognitive Decline in Neurologically Stable Patients with Multiple Sclerosis
Diagnostics, 2021 (1) Background: Cognitive deterioration is an important marker of disease activity in multiple sclerosis (MS). It is vital to detect cognitive decline as soon as possible. Cognitive deterioration can take the form of isolated cognitive decline (ICD) with
Jiri Motyl +11 more
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Longitudinal associations between physical and cognitive performance among community-dwelling older adults. [PDF]
PLoS ONE, 2015 To assess the directionality of the association between physical and cognitive decline in later life, we compared patterns of decline in performance across groups defined by baseline presence of cognitive and/or physical impairment [none (n = 217 ...
Magdalena I Tolea +2 more
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Distinct cytokine profiles across trajectories of self-perceived cognitive impairment among early-stage breast cancer survivors. [PDF]
, 2020 The aim of the current study is to identify distinct cytokine profiles in relation to self-perceived cognitive trajectories. In our study cohort (n = 128), early-stage breast cancer patients were categorized into no impairment reported, acute ...
Chan, Alexandre +3 more
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Cognition: The brain's decline [PDF]
Nature, 2012 Treating cognitive problems common in elderly people requires a deeper understanding of how a healthy brain ages.
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Gait and cognition: mapping the global and discrete relationships in ageing and neurodegenerative disease [PDF]
, 2016 Recent research highlights the association of gait and cognition in older adults but a stronger understanding is needed to discern coincident pathophysiology, patterns of change, examine underlying mechanisms and aid diagnosis.
Bunce, Jennifer +4 more
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Demand Coupling Drives Neurodegeneration: A Model of Age-Related Cognitive Decline and Dementia
Cells, 2022 The societal burden of Alzheimer’s Disease (AD) and other major forms of dementia continues to grow, and multiple pharmacological agents directed towards modifying the pathological “hallmarks” of AD have yielded disappointing results.
Josh Turknett, Thomas R. Wood
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