Results 31 to 40 of about 332,380 (290)

Cognitive decline in Parkinson disease [PDF]

open access: yesNature Reviews Neurology, 2017
Dementia is a frequent problem encountered in advanced stages of Parkinson disease (PD). In recent years, research has focused on the pre-dementia stages of cognitive impairment in PD, including mild cognitive impairment (MCI). Several longitudinal studies have shown that MCI is a harbinger of dementia in PD, although the course is variable, and ...
Byron Creese   +10 more
openaire   +6 more sources

Impacts of baseline biomarkers on cognitive trajectories in subjective cognitive decline: the CoSCo prospective cohort study

open access: yesAlzheimer’s Research & Therapy, 2023
Background Subjective cognitive decline (SCD) is a risk factor for Alzheimer’s disease (AD); however, the rates of cognitive decline are variable according to underlying pathologies and biomarker status.
Yun Jeong Hong   +8 more
doaj   +1 more source

Mediterranean diet and cognitive decline [PDF]

open access: yesPublic Health Nutrition, 2004
AbstractObjective:To investigate the possible role of diet in age-related cognitive decline (ARCD) and cognitive impairment of both degenerative (Alzheimer's disease, AD) and vascular (vascular dementia, VaD) origin.Design:Literature review.Results:In an elderly population of southern Italy with a typical Mediterranean diet, high energy intake of ...
PANZA F   +8 more
openaire   +6 more sources

Isolated Cognitive Decline in Neurologically Stable Patients with Multiple Sclerosis

open access: yesDiagnostics, 2021
(1) Background: Cognitive deterioration is an important marker of disease activity in multiple sclerosis (MS). It is vital to detect cognitive decline as soon as possible. Cognitive deterioration can take the form of isolated cognitive decline (ICD) with
Jiri Motyl   +11 more
doaj   +1 more source

Protocol for a non-randomised pilot and feasibility study evaluating a multicomponent intervention to simplify medication regimens for people receiving community-based home care services

open access: yesBMJ Open, 2019
Introduction Managing medication regimens is one of the most complex and burdensome tasks performed by older people, and can be prone to errors. People living with dementia may require medication administration assistance from formal and informal ...
Sarah N Hilmer   +10 more
doaj   +1 more source

Longitudinal associations between physical and cognitive performance among community-dwelling older adults. [PDF]

open access: yesPLoS ONE, 2015
To assess the directionality of the association between physical and cognitive decline in later life, we compared patterns of decline in performance across groups defined by baseline presence of cognitive and/or physical impairment [none (n = 217 ...
Magdalena I Tolea   +2 more
doaj   +1 more source

Periodontitis and Cognitive Decline in Alzheimer’s Disease [PDF]

open access: yesPLOS ONE, 2016
Periodontitis is common in the elderly and may become more common in Alzheimer's disease because of a reduced ability to take care of oral hygiene as the disease progresses. Elevated antibodies to periodontal bacteria are associated with an increased systemic pro-inflammatory state. Elsewhere raised serum pro-inflammatory cytokines have been associated
Rachel Raybould   +15 more
openaire   +10 more sources

The APOE locus is linked to decline in general cognitive function: 20-years follow-up in the Doetinchem Cohort Study

open access: yesTranslational Psychiatry, 2022
Cognitive decline is part of the normal aging process. However, some people experience a more rapid decline than others due to environmental and genetic factors.
M. Liset Rietman   +11 more
doaj   +1 more source

Demand Coupling Drives Neurodegeneration: A Model of Age-Related Cognitive Decline and Dementia

open access: yesCells, 2022
The societal burden of Alzheimer’s Disease (AD) and other major forms of dementia continues to grow, and multiple pharmacological agents directed towards modifying the pathological “hallmarks” of AD have yielded disappointing results.
Josh Turknett, Thomas R. Wood
doaj   +1 more source

Information Technologies for Cognitive Decline

open access: yes, 2022
Information technology (IT) is used to establish diagnosis and provide treatments for people with cognitive decline. The condition affects many before it becomes clear that more permanent changes, like dementia, could be noticed. Those who search for information are exposed to lots of information and different technologies which they need to make sense
Farsirotos, Gina, Babic, Ankica
openaire   +4 more sources

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