Results 51 to 60 of about 157,006 (266)

High school students’ cognitive load on biology learning: A case study

Assimilation
This study aimed to analyze the cognitive load of high school students on biology learning. The method was used in this research is the survey method. The subjects of the study consisted of 179 students in grade X students consisting of 56 male students ...
Aris Sunandar, Rina Karwatisari, Adi Rahmat, Nanang Winarno, Yanti Hamdiyati   +4 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Performance of a cognitive load inventory during simulated handoffs: Evidence for validity

SAGE Open Medicine, 2016
Background: Advancing patient safety during handoffs remains a public health priority. The application of cognitive load theory offers promise, but is currently limited by the inability to measure cognitive load types.
John Q Young, Christy K Boscardin, Savannah M van Dijk, Ruqayyah Abdullah, David M Irby, Justin L Sewell, Olle Ten Cate, Patricia S O’Sullivan   +7 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

A review of driver cognitive load detection using ECG signals [PDF]

SHS Web of Conferences
Detection of the driver’s cognitive load while driving is crucial to prevent the likelihood of traffic collisions and improve road safety. A physiological-based approach has gained significant attention due to its potential to provide reliable indicators
Tjolleng Amir, Dyota Pramudita Nyoman
doaj   +1 more source

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source

Research Frontiers in Machine Learning & Knowledge Extraction

Machine Learning and Knowledge Extraction
Machine Learning and Knowledge Extraction have evolved from algorithmic tools for pattern recognition into a unifying foundational scientific framework underpinning virtually all of today’s groundbreaking advances, enabling systematic discovery ...
Andreas Holzinger, Luca Longo, Angelo Cangelosi, Javier Del Ser   +3 more
doaj   +1 more source

Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer

Aging and Cancer, EarlyView.
Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss, Alexis C. Wardell, Allison M. Deal, Kirsten A. Nyrop, Allison Ross, Yara G. Abdou, Jeffrey D. Aldrich, Lisa A. Cary, E. Claire Dees, Katherine E. Reeder‐Hayes, Emily M. Ray, Natalia Mitin, Denis Tsygankov   +12 more
wiley   +1 more source

Study on cognitive load of OM interface and eye movement experiment for nuclear power system

Nuclear Engineering and Technology, 2020
The operation and monitoring (OM) interface is the digital medium between nuclear power system and operators. The cognitive load of OM interface has an important effect on the operation errors made by operator during OM task between operator and computer.
Jingling Zhang, Daizhong Su, Yan Zhuang, Furong QIU   +3 more
doaj   +1 more source