Results 51 to 60 of about 3,143,453 (309)

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Instantiating the onEEGwaveLAD Framework for Real-Time Muscle Artefact Identification and Mitigation in EEG Signals

open access: yesSensors
While electroencephalography is extremely useful for studying brain activity, EEG data is always contaminated by a wide range of artefacts. Many techniques exist to identify and remove such artefacts, primarily offline, with and without human supervision
Luca Longo, Richard Reilly
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Advancing Deliberative Discourse Measurement: The Intersection with Computational Abstract Argumentation in Discourse Quality Evaluations

open access: yesSystems
This research investigates the potential of computational argumentation, specifically the application of the Abstract Argumentation Framework (AAF), to enhance the evaluation of deliberative quality in public discourse.
Sanjay Kumar, Jane Suiter, Luca Longo
doaj   +1 more source

Goliath and the Cognitive Load Theory

open access: yesJournal of Computer Languages
A successful teaching effort is usually dependant on several factors. From the right environment, to a precisely worded exercise statement, it rests on the teacher's shoulders the concoction of the most effective learning assets to their students. A significant part of this process lies on practise: students commonly solidify their knowledge by solving
Tiago Carvalho Freitas   +3 more
openaire   +3 more sources

Metastatic niche shaped by host factors influences disseminated cancer cell fate

open access: yesFEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward   +2 more
wiley   +1 more source

A Review on Machine Learning Methods for Customer Churn Prediction and Recommendations for Business Practitioners

open access: yesIEEE Access
Due to market deregulation and globalisation, competitive environments in various sectors continuously evolve, leading to increased customer churn. Effectively anticipating and mitigating customer churn is vital for businesses to retain their customer ...
Awais Manzoor   +3 more
doaj   +1 more source

Pupil dilation as cognitive load measure in instructional videos on complex chemical representations

open access: yesFrontiers in Education, 2023
This secondary analysis of an earlier eye-tracking experiment investigated how triangulating changes in pupil dilation with student-self reports can be used as a measure of cognitive load during instructional videos with complex chemical representations.
Marc Rodemer   +2 more
doaj   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

Assessing Interaction Quality in Human–AI Dialogue: An Integrative Review and Multi-Layer Framework for Conversational Agents

open access: yesMachine Learning and Knowledge Extraction
Conversational agents are transforming digital interactions across various domains, including healthcare, education, and customer service, thanks to advances in large language models (LLMs).
Luca Marconi   +2 more
doaj   +1 more source

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