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Informing: A Cognitive Load Perspective [PDF]

Informing Science: The International Journal of an Emerging Transdiscipline, 2011
Introduction Informing science investigates how to provide clientele with information in a form, format, and schedule that maximizes its effectiveness (Cohen, 1999; 2009). According to its general, cross-disciplinary definition, information is a feature of objects of different nature that describes their structural aspects represented by patterns ...
openaire   +1 more source

Verification-guided modelling of salience and cognitive load

, 2009
Well-designed interfaces use procedural and sensory cues to increase the cognitive salience of appropriate actions. However, empirical studies suggest that cognitive load can influence the strength of those cues.
Curzon, P., Jonathan Back, Rukšėnas, R., Paul Curzon, Back, Jonathan, Blandford, Ann, Rukšėnas, Rimvydas, Curzon, Paul, Ann Blandford, Rimvydas Rukšėnas, Back, J., Blandford, A.   +11 more
core   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

A global model-agnostic rule-based XAI method based on Parameterized Event Primitives for time series classifiers

Frontiers in Artificial Intelligence
Time series classification is a challenging research area where machine learning and deep learning techniques have shown remarkable performance. However, often, these are seen as black boxes due to their minimal interpretability.
Ephrem Tibebe Mekonnen, Ephrem Tibebe Mekonnen, Luca Longo, Luca Longo, Pierpaolo Dondio   +4 more
doaj   +1 more source

The evolution of cognitive load theory and its application to medical education

Perspectives on Medical Education, 2015
Cognitive Load Theory (CLT) has started to find more applications in medical education research. Unfortunately, misconceptions such as lower cognitive load always being beneficial to learning and the continued use of dated concepts and methods can result
Jimmie Leppink, Angelique van den Heuvel
doaj   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

FEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik, Russell Pickford, Hannah C. Timmins, Olivier Piguet, Glenda M. Halliday, Matthew C. Kiernan, Woojin Scott Kim   +6 more
wiley   +1 more source

Computational Argumentation and Automatic Rule-Generation for Explainable Data-Driven Modeling

IEEE Access
The creation of data-driven models for classification problems requires increasing transparency and inferential explainability, especially in high-stakes domains such as health-care, finance, and policy making. Rule-based systems are widely regarded as a
Luca Longo, Serena Berretta, Damiano Verda, Lucas Rizzo   +3 more
doaj   +1 more source

Understanding Cognitive Load Using On-line Dictionaries [PDF]

, 2017
Cognitive Load Theory may useful for language instructors to understand how the look up conditions of using an on-line dictionary might influence learning.
Dilenschneider, Robert F.
core  

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Approximate-Inverse Explainability of β–VAE Latents for Multichannel EEG Participant-Generalised Topographical Representation Learning

IEEE Access
Electroencephalography (EEG) offers millisecond-level resolution of brain activity. However, its clinical utility is limited by artefacts and its non-linear and non-stationary characteristics.
Takafumi Nakanishi, Luca Longo
doaj   +1 more source