Results 81 to 90 of about 157,006 (266)

Elevated Connectivity During Language Processing Is Associated With Cognitive Performance in SeLECTS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Self‐Limited Epilepsy with Centrotemporal Spikes (SeLECTS) is associated with language impairments despite seizures originating in the motor cortex, suggesting aberrant cross‐network interactions. Here we tested whether functional connectivity in SeLECTS during language tasks predicts language performance.
Wendy Qi, Katharine Lee, Kerry C. Nix, Miguel Menchaca, Xiwei Shé, Lorelei Santa Maria, Wei Wu, Zihuai He, Fiona M. Baumer   +8 more
wiley   +1 more source

SPG4 and Dementia: Expanding the Clinical Spectrum

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Hereditary spastic paraplegia (HSP) is a group of disorders characterized by progressive spasticity and lower limb weakness, with mutations in SPG4/SPAST being the most common cause. Detailed studies and clinical and molecular comparisons across different populations are missing.
Emanuele Panza, Arun Meyyazhagan, Eliseo Picchi, Gustavo Ribas, Ingrid Faber, Ryosuke Miyamoto, Preethi Basavaraju, Paolo Eusebi, Haripriya Kuchi Bhotla, Mario Stasi, Fabrizio Gaudiello, Francesco Patti, Filippo Maria Santorelli, Marcondes Cavalcante França Jr, José Luiz Pedroso, Orlando Graziani Povoas Barsottini, Hélio Afonso Ghizoni Teive, Peter Henry St George‐Hyslop, Toshitaka Kawarai, Antonio Orlacchio   +19 more
wiley   +1 more source

Swallowing performance during cognitive tasks in healthy adults

Frontiers in Neurology
ObjectiveDysphagia frequently co-occurs with cognitive impairment, suggesting that swallowing may involve cognitive processes. However, the relationship between cognitive load and swallowing performance remains unclear.
Xiuen Chen, Xiuen Chen, Xiuen Chen, Chenchen Zhang, Wenhui Shi, Wenhui Shi, Zhichao Ning, Zhichao Ning, Jiejiao Zheng, Yongjun Zheng, Yunyun Zhang   +10 more
doaj   +1 more source

ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan, Yan Jiang, Yuxuan Yong, Tianshuo Zhang, Niannian Zhang, Qianqian Zeng, Xue Gong, Li Meng, Fangfang Bi, Yongmin Liu   +9 more
wiley   +1 more source

Corrigendum: Human mental workload: A survey and a novel inclusive definition

Frontiers in Psychology, 2022
Luca Longo, Christopher D. Wickens, Gabriella Hancock, P. A. Hancock   +3 more
doaj   +1 more source

Cognitive Load in Pediatric Critical Care Medicine: Tsunamis and a Thousand Cuts

Critical Care Explorations
IMPORTANCE:. Excessive cognitive load impairs task performance and contributes to burnout, but studies of cognitive load in pediatric critical care medicine (PCCM) settings are limited. OBJECTIVES:. To better understand cognitive load in an academic PCCM
Daniel E. Ehrmann, MD, MS, FABP, Sara N. Gallant, PhD, Sunkyung Yu, MS, Danny Eytan, MD, PhD, Elaine Gilfoyle, MD, FRCPC, Azadeh Assadi, PhD, Seth Gray, MD, FABP, Oshri Zaulan, MD, FRCPC, Mjaye Mazwi, MBChB, FABP   +8 more
doaj   +1 more source

Longitudinal Assessment of Biomarkers in ALS: Discriminative Biomarkers for Disease Progression and Survival

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To assess the association and discriminative performance of serum biomarkers with clinical disease progression and survival in patients with amyotrophic lateral sclerosis (ALS). Methods This retrospective study, conducted at Houston Methodist Hospital, Houston, TX, used longitudinal serum samples collected between January 2018 and ...
David R. Beers, Yueh‐Yun Lin, Jason R. Thonhoff, Aaron D. Thome, Alireza Faridar, Weihua Zhao, Shixiang Wen, Stanley H. Appel   +7 more
wiley   +1 more source

Cognitive load classification of mixed reality human computer interaction tasks based on multimodal sensor signals

Scientific Reports
Evaluating cognitive load in mixed reality (MR) has become a significant challenge in human-computer interaction (HCI). To address this, we established an MR multimodal experimental platform with three distinct environments to induce varying levels of ...
Yukang Hou, Qingsheng Xie, Ning Zhang, Jian Lv   +3 more
doaj   +1 more source

Gender Differences in Cognitive Load when Applying Game-Based Learning with Intelligent Robots

Educational Technology & Society, 2021
The application of artificial intelligence (AI) in education is now widespread, and the use of robots in education has demonstrated a positive influence on students’ behavior and development.
Beyin Chen, Gwo-Haur Hwang, Shen-Hua Wang   +2 more
doaj  

Choroid Plexus Enlargement and USPIO‐Based Inflammatory Feature in Cerebral Small Vessel Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The choroid plexus (CP) is a key component of the blood–cerebrospinal fluid barrier (BCSFB), but its mechanism of action in cerebral small vessel disease (CSVD) remains unclear. This study investigated CP volume (CPV) alterations and their association with conventional imaging markers in CSVD and explored the underlying role of ...
Yongqiang Qu, Xiaoning Ren, Cuihua Fan, Chun Li, Lijie Zhang, Zaiqiang Zhang, Shaowu Li, Zhongmeng Lai, Bin Cai, Ying Fu, Yi Lin, Zhibao Zhu   +11 more
wiley   +1 more source