Results 131 to 140 of about 31,924 (248)

Cohesin loops DNA [PDF]

The Journal of Cell Biology, 2006
![][1] The large distance between two loci (green) in rec8− cells indicates decompacted chromosomes. The glue that holds together sister chromatids also compacts meiotic chromosomes, according to Ding et al. on page [499][2].
openaire   +1 more source

Cohesin-interacting protein WAPL-1 regulates meiotic chromosome structure and cohesion by antagonizing specific cohesin complexes

eLife, 2016
Wapl induces cohesin dissociation from DNA throughout the mitotic cell cycle, modulating sister chromatid cohesion and higher-order chromatin structure.
Oliver Crawley, Consuelo Barroso, Sarah Testori, Nuria Ferrandiz, Nicola Silva, Maikel Castellano-Pozo, Angel Luis Jaso-Tamame, Enrique Martinez-Perez   +7 more
doaj   +1 more source

Oncogenic C-Myc Induces Replication Stress by Increasing Cohesins Chromatin Occupancy at Ctcf Sites

, 2022
Silvia Peripolli, Tanya Singh, Harshil Patel, Letícia Meneguello, Koshiro Kiso, Peter H. Thorpe, Cosetta Bertoli, Robertus Antonius Maria de Bruin   +7 more
openalex   +1 more source

Structural characterization of a novel autonomous cohesin fromRuminococcus flavefaciens [PDF]

, 2014
Milana Voronov‐Goldman, Maly Levy-Assaraf, Oren Yaniv, Gloria Wisserman, Sadanari Jindou, Ilya Borovok, Edward A. Bayer, Raphael Lamed, Linda J. W. Shimon, Felix Frolow   +9 more
openalex   +1 more source

APC/C-Cdc20 mediates deprotection of centromeric cohesin at meiosis II in yeast [PDF]

, 2017
Katarzyna Jonak, Ievgeniia Zagoriy, Tugce Oz, Peter Graf, Julie Rojas, Valentina Mengoli, Wolfgang Zachariae   +6 more
openalex   +1 more source

Supplementary Figures 1-7 from ATM Regulation of the Cohesin Complex Is Required for Repression of DNA Replication and Transcription in the Vicinity of DNA Double-Strand Breaks

, 2023
Thomas E. Bass, Donald E. Fleenor, Paige E. Burrell, Michael B. Kastan   +3 more
openalex   +1 more source

Intertwined Functions of Separase and Caspase in Cell Division and Programmed Cell Death. [PDF]

, 2020
Timely sister chromatid separation, promoted by separase, is essential for faithful chromosome segregation. Separase is a member of the CD clan of cysteine proteases, which also includes the pro-apoptotic enzymes known as caspases.
Jeong, Pan Young, Joshi, Pradeep M, Kumar, Ashish, Rothman, Joel H   +3 more
core   +1 more source

The kinetochore is an enhancer of pericentric cohesin binding.

PLoS Biology, 2004
The recruitment of cohesins to pericentric chromatin in some organisms appears to require heterochromatin associated with repetitive DNA. However, neocentromeres and budding yeast centromeres lack flanking repetitive DNA, indicating that cohesin ...
Stewart A Weber, Jennifer L Gerton, Joan E Polancic, Joseph L DeRisi, Douglas Koshland, Paul C Megee   +5 more
doaj   +1 more source

Enhanced RAD21 cohesin expression confers poor prognosis in BRCA2 and BRCAX, but not BRCA1 familial breast cancers [PDF]

, 2012
Max Yan, Huiling Xu, Nicola Waddell, Kristy Shield‐Artin, Izhak Haviv, Michael J. McKay, Stephen B. Fox, Stephen B Fox   +7 more
openalex   +1 more source

Cohesin cleavage by separase is enhanced by a substrate motif distinct from the cleavage site. [PDF]

, 2019
Chromosome segregation begins when the cysteine protease, separase, cleaves the Scc1 subunit of cohesin at the metaphase-to-anaphase transition.
Asfaha, Jonathan B, Campbell, Melody G, Cheng, Yifan, Ghent, Chloe M, Klebba, Joseph E, Morgan, David O, Rosen, Laura E   +6 more
core   +1 more source