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Colchicine and the heart [PDF]
European Heart Journal, 2021 Abstract Colchicine is a unique, sophisticated anti-inflammatory agent that has been used for decades for the prevention of acute inflammatory flares in gout and familial Mediterranean fever. In recent years, clinical trials have demonstrated its potential in a range of cardiovascular (CV) conditions.
Massimo Imazio, Mark Nidorf
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Colchicine for pericarditis [PDF]
Cochrane Database of Systematic Reviews, 2014 Pericarditis is the inflammation of the pericardium, the membranous sac surrounding the heart. Recurrent pericarditis is the most common complication of acute pericarditis, causing severe and disabling chest pains. Recurrent pericarditis affects one in three patients with acute pericarditis within the first 18 months.
Alabed, S +4 more
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Frontiers in Pharmacology, 2021 Background: The beneficial effects of colchicine on cardiovascular disease have been widely reported in recent studies. Previous research demonstrated that colchicine has a certain protective effect on ischemic myocardium and has the potential to treat ...
Yuanjun Tang +8 more
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Effect of Colchicine on Secondary Acute Lung Injury in an Experimental Sepsis Model in Rats
Mediterranean Journal of Infection, Microbes and Antimicrobials, 2023 Introduction: An irregular systemic inflammatory response in sepsis can induce acute lung injury (ALI), which is characterized by the exaggerated inflammation of the lung tissue.
Mehmet CEYLAN +4 more
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AGRIVITA Journal of Agricultural Science, 2023 This research aimed to induce in vitro and identify polyploidy plantlets of Porang (Amorphophallus muelleri Blume) after colchicine treatment.
Wahyu Widoretno +3 more
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Frontiers in Cardiovascular Medicine, 2022 BackgroundThis study investigated the effect of colchicine use on the risks of heart disease (HD), pericarditis, endocarditis, myocarditis, cardiomyopathy, cardiac arrhythmia, and cardiac failure in patients having interstitial lung disease (ILD) with ...
Jun-Jun Yeh +11 more
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Inhibition of the Glycine Receptor alpha 3 Function by Colchicine
Frontiers in Pharmacology, 2020 Colchicine is a plant alkaloid that is widely used as a therapeutic agent. It is widely accepted that colchicine reduces the production of inflammatory mediators mainly by altering cytoskeleton dynamics due to its microtubule polymerization inhibitory ...
Carola Muñoz-Montesino +11 more
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Arthritis & Rheumatism, 1991 The purpose of this discussion is to examine these two concerns, the efficacy and safety of colchicine, in the context of this controversy.
Gene V. Ball, Larry W. Moreland
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Radioimmunoassay of colchicine [PDF]
Biochemical Journal, 1975 Antibodies to cholchicine were raised in rabbits after injection of N-desacetylthiocolchicine conjugated to bovine serum albumin. Antisera diluted 1:100 bound 50% of 1.6ng of [3H]colchicine. Cross-reaction of the antisera with colchicine derivatives and other drugs was measured and a radioimmunoassay of colchicine in biological fluids was proposed.
Duprey F, Bohuon C, Boudène C
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Colchicine Impacts Leukocyte Trafficking in Atherosclerosis and Reduces Vascular Inflammation
Frontiers in Immunology, 2022 BackgroundInflammation strongly contributes to atherosclerosis initiation and progression. Consequently, recent clinical trials pharmacologically targeted vascular inflammation to decrease the incidence of atherosclerosis-related complications ...
Ulrike Meyer-Lindemann +23 more
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