Results 1 to 10 of about 50,322 (265)
Colchicine and coronary heart disease risks: A meta-analysis of randomized controlled clinical trials [PDF]
Frontiers in Cardiovascular Medicine, 2022 BackgroundSeveral trials have considered the safety and clinical benefits of colchicine as a treatment option for secondary prevention in patients with coronary atherosclerotic heart disease (CAD), but its safety and clinical benefits remain ...
Zijun Ma, Jun Chen, Kaiqin Jin, Xin Chen
doaj +2 more sources
RMD Open, 2021 Objective To evaluate whether the addition of colchicine to standard treatment for COVID-19 results in better outcomes.Design We present the results of a randomised, double-blinded, placebo-controlled clinical trial of colchicine for the treatment of ...
Maria Isabel Lopes +2 more
exaly +3 more sources
Critical appraisal of "Colchicine for the secondary prevention of cardiovascular diseases: a cumulative-dose meta-analysis of randomized controlled trials including 31,397 subjects worldwide". [PDF]
Ann Med Surg (Lond)Amjad A, Junaid M, Ali U, Khalid M.
europepmc +2 more sources
Frontiers in Pharmacology, 2021 Background: The beneficial effects of colchicine on cardiovascular disease have been widely reported in recent studies. Previous research demonstrated that colchicine has a certain protective effect on ischemic myocardium and has the potential to treat ...
Yuanjun Tang +8 more
doaj +1 more source
Effect of Colchicine on Secondary Acute Lung Injury in an Experimental Sepsis Model in Rats
Mediterranean Journal of Infection, Microbes and Antimicrobials, 2023 Introduction: An irregular systemic inflammatory response in sepsis can induce acute lung injury (ALI), which is characterized by the exaggerated inflammation of the lung tissue.
Mehmet CEYLAN +4 more
doaj +1 more source
AGRIVITA Journal of Agricultural Science, 2023 This research aimed to induce in vitro and identify polyploidy plantlets of Porang (Amorphophallus muelleri Blume) after colchicine treatment.
Wahyu Widoretno +3 more
doaj +1 more source
Inhibition of the Glycine Receptor alpha 3 Function by Colchicine
Frontiers in Pharmacology, 2020 Colchicine is a plant alkaloid that is widely used as a therapeutic agent. It is widely accepted that colchicine reduces the production of inflammatory mediators mainly by altering cytoskeleton dynamics due to its microtubule polymerization inhibitory ...
Carola Muñoz-Montesino +11 more
doaj +1 more source
Frontiers in Cardiovascular Medicine, 2022 BackgroundThis study investigated the effect of colchicine use on the risks of heart disease (HD), pericarditis, endocarditis, myocarditis, cardiomyopathy, cardiac arrhythmia, and cardiac failure in patients having interstitial lung disease (ILD) with ...
Jun-Jun Yeh +11 more
doaj +1 more source
International Journal of Cardiology: Heart & Vasculature, 2023 Background: Colchicine has anti-inflammatory properties, but its utility in improving cardiovascular outcomes has been disputed. Here, we study the impact of colchicine on cardiovascular outcomes in patients with gout with and without coronary artery ...
Muhammad U. Siddiqui +5 more
doaj +1 more source
Frontiers in Pharmacology, 2019 Objectives: A previous study suggested that colchicine may cause leukopenia and increase the risk of infection, such as pneumonia. Thus, we investigated the potential relationship between colchicine use and risk of developing pneumonia.Methods: Data were
Tsung-Lin Tsai +8 more
doaj +1 more source