Results 111 to 120 of about 86,831 (312)
Anti-IL1 in patients with low penetrance mutations for autoinflammatory diseases: tuscany and sicilian case series from paediatric to adult age [PDF]
, 2017 Patients with low penetrance mutations for Autoinflammatory syndromes (AID) can have severe clinical manifestations, which require to be treated with biological drugs anti-IL-1.
Giovanni Corsello +4 more
core
Herbicide effects on freshwater benthic diatoms: Induction of nucleus alterations and silica cell wall abnormalities [PDF]
, 2008 Benthic diatoms are well known bio-indicators of river pollution by nutrients (nitrogen and phosphorus). Biological indexes, based on diatom sensitivity for non-toxic pollution, have been developed to assess the water quality.Nevertheless, they are not ...
Coste, Michel +4 more
core +2 more sources
Environmental and Molecular Mutagenesis, EarlyView.Abstract Quantitative risk assessments of chemicals are routinely performed using in vivo data from rodents; however, there is growing recognition that non‐animal approaches can be human‐relevant alternatives. There is an urgent need to build confidence in non‐animal alternatives given the international support to reduce the use of animals in toxicity ...
Marc A. Beal +14 more
wiley +1 more source
Bitter Taste Receptor Agonists Induce Apoptosis in Papillary Thyroid Cancer
Head &Neck, EarlyView.ABSTRACT Background Papillary thyroid carcinoma (PTC) is the most common thyroid malignancy, with a 20% recurrence rate. Bitter taste receptors (T2Rs) and their genes (TAS2Rs) may regulate survival in solid tumors. This study examined T2R expression and function in PTC cells.
Kimberly Wei +6 more
wiley +1 more source
Colchicine Overdose in a Suicidal Attempt [PDF]
International Journal of Medical Toxicology and Forensic Medicine, 2019 Colchicine overdose is uncommon; however, it can cause serious adverse effects and even death. Colchicine inhibits microtubule polymerization, causing mitotic spindle disruption.
Fatemeh Eghbali +6 more
doaj
Hemophagocytic lymphohistiocytosis and Pelger-Huët anomaly associated with colchicine intoxication
Hematology Reports, 2014 Colchicine is frequently used in the treatment of familial Mediterranean fever (FMF). First symptoms of colchicine intoxication are gastrointestinal disturbances, such as abdominal cramps, diarrhea, pancytopenia and so on.
Baris Malbora +2 more
doaj +1 more source
Safety Evaluation of Serendipity Berry Sweet Protein From Komagataella phaffii
Journal of Applied Toxicology, EarlyView.ABSTRACT Serendipity Berry Sweet Protein (sweelin) is a novel hyper‐sweet thermophilic protein designed using Artificial Intelligence Computational Protein Design (AI‐CPD) to improve the stability and sensory profile of the protein found in serendipity berry (Dioscoreophyllum cumminsii).
Yael Lifshitz +12 more
wiley +1 more source
CENH3-GFP: a visual marker for gametophytic and somatic ploidy determination in Arabidopsis thaliana [PDF]
, 2016 Background: The in vivo determination of the cell-specific chromosome number provides a valuable tool in several aspects of plant research. However, current techniques to determine the endosystemic ploidy level do not allow non-destructive, cell-specific
Angenon, Geert +4 more
core +5 more sources
The conversion of colchicine into colchiceine [PDF]
, 1938 Eric Boyland, Elinor Huntsman Mawson
openalex +1 more source
Journal of Applied Toxicology, EarlyView.ABSTRACT Gastrointestinal health is one of the fastest growing areas in the food and beverage industry, as its importance to overall health and well‐being is becoming increasingly recognized. Immunoglobulins play a key role in protecting the gastrointestinal tract, and nonbovine sources of immunoglobulins (including camel milk, which has a long history
Kirt R. Phipps +8 more
wiley +1 more source