Results 111 to 120 of about 77,446 (306)

Beneficial effects of colchicine for moderate to severe COVID-19: an interim analysis of a randomized, double-blinded, placebo controlled clinical trial

medRxiv, 2020
Introduction. Neutrophilia and high levels of proinflammatory cytokines and other mediators of inflammation are common finds in patients with severe acute respiratory syndrome due to COVID-19.
Maria IF Lopes, L. Bonjorno, M. Giannini, N. Amaral, M. Benatti, U. C. Rezek, Laerte L Emrich Filho, B. A. Sousa, S. C. Almeida, R. Luppino-Assad, F. Veras, Ayda Scheider, T. Rodrigues, L. Leiria, L. D. Cunha, J. Alves-Filho, T. Cunha, Eurico Arruda Neto, C. H. Miranda, A. Pazin-Filho, M. Martins, M. Borges, B. Fonseca, V. Bollela, F. Cunha, D. Zamboni, R. Santana, F. Vilar, P. Louzada-Júnior, R. Oliveira   +29 more
semanticscholar   +1 more source

Safety Evaluation of Serendipity Berry Sweet Protein From Komagataella phaffii

Journal of Applied Toxicology, EarlyView.
ABSTRACT Serendipity Berry Sweet Protein (sweelin) is a novel hyper‐sweet thermophilic protein designed using Artificial Intelligence Computational Protein Design (AI‐CPD) to improve the stability and sensory profile of the protein found in serendipity berry (Dioscoreophyllum cumminsii).
Yael Lifshitz, Shira Paz, Rotem Saban, Inbar Zuker, Hagay Shmuely, Katy Gorshkov, Jwar Meetro, Shahrzad Tafazoli, Trung Vo, Gabriela Amiram, Carmit Shani Levi, Uri Lesmes, Ilan Samish   +12 more
wiley   +1 more source

The role of physical exercise in diseases treated with colchicine - an ancient drug with novel clinical applications

Quality in Sport
Colchicine, a lipid-soluble alkaloid derived from Colchicum autumnale, has a long history of use dating back to ancient Egypt. Traditionally used to alleviate pain and swelling, colchicine is now administered for various diseases, including gout and ...
Julia Rejdych, Katarzyna Podyma, Sara Rosołowska-Żak, Maria Sambura, Wiktoria Sas, Gracja Ryznar, Piotr Pierzchała, Michalina Minkowska, Krystyna Chimiak, Gabriela Bylica   +9 more
doaj   +1 more source

Colchicine’s effects on metabolic and inflammatory molecules in adults with obesity and metabolic syndrome: results from a pilot randomized controlled trial

International Journal of Obesity, 2020
Objective Recent clinical trials have demonstrated that colchicine may have metabolic and cardiovascular and benefits in at-risk patients; however, the mechanisms through which colchicine may improve outcomes are still unclear.
A. Demidowich, J. Levine, R. Apps, Foo Cheung, Jinguo Chen, G. Fantoni, Huizhi Rongye Poorani John Yasmine Zhou Shi Subramanian Tsang Belkaid, Huizhi Zhou, R. Shi, P. Subramanian, J. Tsang, Y. Belkaid, T. Patel, J. Yanovski   +13 more
semanticscholar   +1 more source

Allergenicity, Genotoxicity and Subchronic Toxicity Assessment of IgG Binding Protein LT Produced From Aspergillus oryzae

Journal of Applied Toxicology, EarlyView.
ABSTRACT Gastrointestinal health is one of the fastest growing areas in the food and beverage industry, as its importance to overall health and well‐being is becoming increasingly recognized. Immunoglobulins play a key role in protecting the gastrointestinal tract, and nonbovine sources of immunoglobulins (including camel milk, which has a long history
Kirt R. Phipps, Sachin Patel, Kevin Scaife, Toby Holmes, Alica Šoltésová, Sandra Wingaard Thrane, Louise Kristine Vigsnæs, Nigel Baldwin, Christel Jørgensen   +8 more
wiley   +1 more source

Colchicine plus Dapsone in Colchicine‐Resistant FMF Patients

Case Reports in Rheumatology, 2019
Five to ten percent of FMF patients have unfavorable response to the colchicine as a standard therapy. Biologic treatments have been shown to be highly effective, but there are often unavailable, because the price is unaffordably high. This study shows the striking effect of combined dapsone and colchicine therapy in such patients and recommends it as ...
Farhad Salehzadeh, A. Enteshary, M. Moshkbar   +2 more
openaire   +3 more sources

Colchicine may not be effective in COVID-19 infection; it may even be harmful?

Clinical Rheumatology, 2020
Dear Editor, Nowadays, the novel coronavirus disease 2019 (COVID19) pandemic is spreading rapidly all over the world. The search for drugs against COVID-19 is continuing.
M. Cumhur Cure, A. Kucuk, Erkan Cüre
semanticscholar   +1 more source

Hemophagocytic lymphohistiocytosis and Pelger-Huët anomaly associated with colchicine intoxication

Hematology Reports, 2014
Colchicine is frequently used in the treatment of familial Mediterranean fever (FMF). First symptoms of colchicine intoxication are gastrointestinal disturbances, such as abdominal cramps, diarrhea, pancytopenia and so on.
Baris Malbora, Emine Polat, Sare Gulfem Akyuz   +2 more
doaj   +1 more source

Ueber Colchicin [PDF]

Archiv der Pharmazie
n ...
openaire   +4 more sources

Nochmals „Colchicin”︁ in Bier [PDF]

Archiv der Pharmazie, 1877
n ...
openaire   +3 more sources