Results 121 to 130 of about 77,446 (306)

Livedoid Vasculopathy Successfully Treated With JAK Inhibitors

JEADV Clinical Practice, EarlyView.
ABSTRACT Livedoid vasculopathy is a rare thrombotic disease of the small blood vessels. It manifests as fixed violaceous macules, noninflammatory retiform purpura, painful ulcers, and white atrophic scars on the lower extremities. The pathophysiology involves the type 1 interferon pathway. Many patients do not improve with oral anticoagulants.
Antoine Delpuech, Emilie Tournier, Pierre Sohier, Nicolas Dupin, Chloe Challamel, Sara Altandi, Serge Boulinguez, Carle Paul   +7 more
wiley   +1 more source

The Superiority of Compressed Colchicine Tablets over Coated Colchicine Tablets for Familial Mediterranean Fever

Medicina
Background and Objectives: Familial Mediterranean fever (FMF) is an inherited autoinflammatory disease characterized by recurrent febrile attacks and serosal inflammation.
Mehmet Nur Kaya, Muhammed Canbaş, Özlem Kılıç, Abdullah Doğan, Sedat Yılmaz   +4 more
doaj   +1 more source

Hypersensitivity to Colchicine [PDF]

Annals of the Rheumatic Diseases, 1947
L. Phillips, J. G. Macleod
openaire   +4 more sources

Erythema Nodosum in Hidradenitis Suppurativa: A Case Series

JEADV Clinical Practice, EarlyView.
ABSTRACT Hidradenitis suppurativa (HS) is a chronic inflammatory condition linked to dermatologic and multisystem comorbidities, including pyoderma gangrenosum, arthritis, inflammatory bowel disease, and Behcet's disease. While associations with immunological and inflammatory conditions are less frequently reported, erythema nodosum (EN) has an ...
Katie K. Lovell, Sujeeth Shanmugam, Steven R. Feldman, Rita Pichardo   +3 more
wiley   +1 more source

Whole‐exome sequencing in families from Lifou Island (New Caledonia) reveals candidate variants involved in gout pathogenesis

Rheumatology &Autoimmunity, EarlyView.
Strategy to identify variants involved in gout pathogenesis in New Caledonia. Abstract Background Gout, which manifests as severe inflammation caused by excessive serum urate levels and monosodium urate deposits in the joints, is associated with multiple genomic loci in Europeans.
Philippe Georgel, Yves‐Marie Ducrot, Anne Molitor, Nicodème Paul, Lydie Naegely, Antoine Hanauer, Thomas Bardin, Gaston Rijo de Leon, Etienne Patin, Luis Quintana‐Murci, Mariko Matsui, Marc Jouan, Seiamak Bahram, Raphael Carapito   +13 more
wiley   +1 more source

Structure of Colchicine [PDF]

Nature, 1945
IN view of the remarkable physiological properties of colchicine its chemical nature is of some interest. Until recently, the structure (I) proposed by Windaus1 has been generally accepted, although the stability of colchicine did not suggest a 9-amino-9: 10-dihydrophenanthrene system, and although the salicylaldehyde enol structure of ring C appeared ...
openaire   +4 more sources

Colchicine Overdose in a Suicidal Attempt [PDF]

International Journal of Medical Toxicology and Forensic Medicine, 2019
Colchicine overdose is uncommon; however, it can cause serious adverse effects and even death. Colchicine inhibits microtubule polymerization, causing mitotic spindle disruption.
Fatemeh Eghbali, Reza Bidaki, Sina Negintaji, Maryam Dehghani, Adeleh Sahebnasagh, Ali Asghar Bagheri Atabak, Fatemeh Saghafi   +6 more
doaj  

Colchicine effect on the DNA content and stomata size of Glycyrrhiza glabra var.glandulifera and Carthamus tinctorius L. cultured in vitro

Journal of Genetic Engineering and Biotechnology, 2015
In vitro induction of polyploids using colchicine causes an increase in DNA content in plants. This is of high importance especially for plants that have medicinal and commercial values. Seeds of two medicinal plants, licorice Glycyrrhiza glabra L.
Nahid Moghbel, Maasoumeh Khalili Borujeni, Françoise Bernard   +2 more
doaj   +1 more source

Colchicine and the Heart

Journal of the American College of Cardiology, 2013
Colchicine, a natural and ancient drug still used today, is traditionally considered the staple therapy for gout and a second-line treatment for pericarditis, as well as a basic part of familial Mediterranean fever and Behcet's disease management. It is commonly classified as an anti-inflammatory agent, although its mechanism of action does not involve
Charalampos Kossyvakis, Spyridon Deftereos, Michael W. Cleman, Konstantinos Raisakis, Georgios Giannopoulos, Nikolaos Papoutsidakis, Christodoulos Stefanadis, Vasiliki Panagopoulou   +7 more
openaire   +3 more sources

Effect of Anakinra on Recurrent Pericarditis Among Patients With Colchicine Resistance and Corticosteroid Dependence: The AIRTRIP Randomized Clinical Trial.

Journal of the American Medical Association (JAMA), 2016
Importance Anakinra, an interleukin 1β recombinant receptor antagonist, may have potential to treat colchicine-resistant and corticosteroid-dependent recurrent pericarditis.
A. Brucato, M. Imazio, M. Gattorno, G. Lazaros, S. Maestroni, M. Carraro, M. Finetti, D. Cumetti, A. Carobbio, N. Ruperto, R. Marcolongo, M. Lorini, A. Rimini, A. Valenti, G. Erre, M. Sormani, R. Belli, F. Gaita, A. Martini   +18 more
semanticscholar   +1 more source