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IN view of the remarkable physiological properties of colchicine its chemical nature is of some interest. Until recently, the structure (I) proposed by Windaus1 has been generally accepted, although the stability of colchicine did not suggest a 9-amino-9: 10-dihydrophenanthrene system, and although the salicylaldehyde enol structure of ring C appeared ...
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Colchicine, a natural and ancient drug still used today, is traditionally considered the staple therapy for gout and a second-line treatment for pericarditis, as well as a basic part of familial Mediterranean fever and Behcet's disease management. It is commonly classified as an anti-inflammatory agent, although its mechanism of action does not involve
Charalampos Kossyvakis+7 more
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In vitro induction of polyploids using colchicine causes an increase in DNA content in plants. This is of high importance especially for plants that have medicinal and commercial values. Seeds of two medicinal plants, licorice Glycyrrhiza glabra L.
Nahid Moghbel+2 more
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Review: Colchicine, Current Advances and Future Prospects [PDF]
Ade R, Rai MK. 2010. Colchicine, current advances and future prospects. Nusantara Bioscience 2: 90-96. Colchicine isa toxic natural compound and secondary metabolite commonly produced by plants like Colchicum autumnale and Gloriosa superba.
ADE, R. (RAVINDRA)+1 more
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Role of the cellular environment in interstitial stem cell proliferation in Hydra [PDF]
The role of the cellular environment on hydra stem cell proliferation and differentiation was investigated by introduction of interstitial cells into host tissue of defined cellular composition.
Bosch, Thomas C. G.+3 more
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Multiple cutaneous manifestations have been linked with COVID‐19, including cutaneous vasculitis, ranging from mild or asymptomatic to fulminant. We conducted a comprehensive study investigating the cutaneous and histopathological manifestations of vasculitis in 33 patients with COVID‐19.
Reem Diab+8 more
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Effects of colchicine and related substances on cell division [PDF]
Austin M. Brues, Aaron A. Cohen
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Abstract Post‐COVID‐19 condition (PCC), also known as long COVID, is a complex multiple organ system condition that can develop and persist for months after acute COVID‐19. PCC encompasses a wide range of symptoms, resulting in heterogeneous clinical manifestations. These manifestations likely arise from diverse underlying pathophysiological mechanisms,
Larissa E Vlaming‐van Eijk+5 more
wiley +1 more source
Response of Pineapple Callus (Ananas comosus Merr.) through In-Vitro Colchicines Treatment
Pineapple Plant (Ananas comosus (L.) Merr) is a fruit plant that has a high economic value. Increased variety of pineapple preparations lead to increased demand for pineapple fruit.
Nurul Istiqomah, Muh. Shofi
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Acute colchicine intoxication complicated with complete AV block
Colchicine, is an old and well-known drug, used for treatment of rheumatic diseases. Nausea, vomiting, abdominal pain, and diarrhea are the clinical symptoms of colchicine poisoning. Cardiotoxicity can lead to mortality.
İlker Ertuğrul+7 more
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