Results 21 to 30 of about 50,322 (265)
Kaohsiung Journal of Medical Sciences, 2015 Microtubules are an ideal target for anticancer drugs because of their essential role in mitosis. Colchicine is a microtubule destabilizer. Whether the clinically acceptable colchicine concentrations had anticancer effects on human cholangiocarcinoma ...
Chun-Chieh Wu +3 more
doaj +1 more source
Rekayasa, 2023 Pumpkin (Cucurbita moschene Duthene) is plant sources of food that has high nutrition content. Increasing the productivity of pumpkin can be done through programs, which is the ploidy manipulation technique, the technique using a mutagen, namely ...
Reza Prakoso Dwi Julianto +2 more
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The etiology and autopsy findings in Colchicine intoxication-related deaths
Medicine Science, 2016 Colchicine is a drug which has a very narrow therapeutic range. This drug has been commonly used for Familial Mediterranean Fever (FMF), Behcets disease, gout arthritis and acute pseudo gout attacks.
Servet Birgin Iritas +7 more
doaj +1 more source
Transcriptome analysis reveals plant response to colchicine treatment during on chromosome doubling
Scientific Reports, 2017 Colchicine was commonly used to artificially double chromosomes while the transcriptome changes in colchicine treated plants has rarely been characterized.
Kai Zhou +4 more
doaj +1 more source
Exploring the Origin of Differential Binding Affinities of Human Tubulin Isotypes αβII, αβIII and αβIV for DAMA-Colchicine Using Homology Modelling, Molecular Docking and Molecular Dynamics Simulations. [PDF]
PLoS ONE, 2016 Tubulin isotypes are found to play an important role in regulating microtubule dynamics. The isotype composition is also thought to contribute in the development of drug resistance as tubulin isotypes show differential binding affinities for various anti-
Bajarang Vasant Kumbhar +3 more
doaj +1 more source
Scientific Reports, 2022 This study aimed to determine the effect of colchicine use on the risk of stroke among patients with diabetes mellitus (DM). We retrospectively enrolled patients with DM between 2000 and 2013 from the Longitudinal Health Insurance Database and divided ...
Jun-Jun Yeh +5 more
doaj +1 more source
Future Science OA, 2021 Purpose: To evaluate the impact of colchicine on sympathetic denervation after acute myocardial infarction (AMI). Materials & methods: Ischemia/Reperfusion was induced in C57BL/6J male mice.
Fabien Huet +6 more
doaj +1 more source
Colchicine-Related Polyneuropathy and Multiple Organ Failure
Türk Nöroloji Dergisi, 2013 Colchicine arrests microtubule assembly and inhibits many cellular functions. This drug is used to treat gout and and Familial Mediterranean Fever. Its gastrointestinal side effects are frequent but more severe adverse effects such as neuropathy and ...
Ersel Dağ, Yakup Türkel, Burcu Gökçe
doaj +1 more source
Colchicine-induced myoneuropathy in a cyclosporine-treated renal transplant recipient
Kidney Research and Clinical Practice, 2013 Colchicine is a relatively safe medication that is widely used for both prevention and treatment of gout attack. However, serious adverse events, including myoneuropathy and multiorgan failure, have been reported.
Kyungmin Huh +6 more
doaj +1 more source
Assessing the Impact of Colchicine on Pulmonary Fibrosis Using Imaging in Patients With Moderate-to-Severe COVID-19 Pneumonia. [PDF]
Can Respir JObjective Pulmonary fibrosis may develop in patients with severe clinical conditions, especially those with high inflammatory indicators. We aimed to investigate the 15‐month follow‐up clinical outcomes in patients with moderate‐to‐severe COVID‐19 pneumonia treated with colchicine and to evaluate its potential in preventing post‐COVID pulmonary ...
Ayhan Albayrak G, Bardakci MI, Temel U.
europepmc +2 more sources