Results 21 to 30 of about 51,001 (266)
The etiology and autopsy findings in Colchicine intoxication-related deaths
Medicine Science, 2016 Colchicine is a drug which has a very narrow therapeutic range. This drug has been commonly used for Familial Mediterranean Fever (FMF), Behcets disease, gout arthritis and acute pseudo gout attacks.
Servet Birgin Iritas +7 more
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Exploring the Origin of Differential Binding Affinities of Human Tubulin Isotypes αβII, αβIII and αβIV for DAMA-Colchicine Using Homology Modelling, Molecular Docking and Molecular Dynamics Simulations. [PDF]
PLoS ONE, 2016 Tubulin isotypes are found to play an important role in regulating microtubule dynamics. The isotype composition is also thought to contribute in the development of drug resistance as tubulin isotypes show differential binding affinities for various anti-
Bajarang Vasant Kumbhar +3 more
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Transcriptome analysis reveals plant response to colchicine treatment during on chromosome doubling
Scientific Reports, 2017 Colchicine was commonly used to artificially double chromosomes while the transcriptome changes in colchicine treated plants has rarely been characterized.
Kai Zhou +4 more
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Scientific Reports, 2022 This study aimed to determine the effect of colchicine use on the risk of stroke among patients with diabetes mellitus (DM). We retrospectively enrolled patients with DM between 2000 and 2013 from the Longitudinal Health Insurance Database and divided ...
Jun-Jun Yeh +5 more
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Future Science OA, 2021 Purpose: To evaluate the impact of colchicine on sympathetic denervation after acute myocardial infarction (AMI). Materials & methods: Ischemia/Reperfusion was induced in C57BL/6J male mice.
Fabien Huet +6 more
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Successfully Treated Severe Colchicine Intoxication in an Adolescent
Türk Yoğun Bakim Derneği Dergisi, 2022 The contain is extracted from the autumn crocus plant, colchicine that an anti-inflammatory drug. The use of colchicine impairs mobilization and activation of neutrophil and supporting treating from some rheumatological diseases especially in childhood ...
Hatice Feray Arı +2 more
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Frontiers in PharmacologyBackgroundCurrently, there remains substantial controversy in research regarding whether the concomitant use of colchicine and statins increases the occurrence of rhabdomyolysis, warranting further substantiation.ObjectiveThis study aimed to identify the
Sha Zhang +4 more
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Colchicine-induced myoneuropathy in a cyclosporine-treated renal transplant recipient
Kidney Research and Clinical Practice, 2013 Colchicine is a relatively safe medication that is widely used for both prevention and treatment of gout attack. However, serious adverse events, including myoneuropathy and multiorgan failure, have been reported.
Kyungmin Huh +6 more
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BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma
FEBS Open Bio, EarlyView.The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru +6 more
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Cardiovascular Therapeutics, 2022 Aim. Colchicine as an anti-inflammatory drug might be effective in the treatment of atherosclerosis, an inflammatory-based condition. The aim of this systematic review and meta-analysis was to evaluate the impact of colchicine on acute coronary syndrome (
Erfan Razavi +3 more
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