Results 71 to 80 of about 1,240,466 (302)

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Colorimetric Method Based on CeO2/CoOOH Nanozyme for Rapid Detection of Ascorbic Acid in Fruits [PDF]

Shipin Kexue
In this study, cerium dioxide-modified cobalt oxyhydroxide (CeO2/CoOOH) nanomaterial was synthesized by a liquid-phase precipitation method. CeO2/CoOOH showed good oxidase-like activity toward 3,3’,5,5’-tetramethylbenzidine (TMB), and could directly ...
YUE Xiaoyue, WU Chaoyun, YAN Shuliang, FU Long, ZHAO Dianbo
doaj   +1 more source

Transient events in bright debris discs: Collisional avalanches revisited [PDF]

, 2017
A collisional avalanche is set off by the breakup of a large planetesimal, releasing small unbound grains that enter a debris disc located further away from the star, triggering there a collisional chain reaction that can potentially create detectable ...
Kral, Quentin, Thebault, Philippe
core   +2 more sources

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

Molecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata, Koji Ando, Hirofumi Hasuda, Koshi Mimori, Elizabeth C. Unan, Siddhartha Pulukuri, Aahana Tiku, Allison Berger, Eiji Oki, Ajit Bharti, Tomoharu Yoshizumi   +10 more
wiley   +1 more source

Physiological Characteristics and Transcriptomic Analysis of Saccharomyces cerevisiae under Carvacrol Stress [PDF]

Shipin Kexue
This study investigated the effect of carvacrol stress on the physiological characteristics and transcriptome of Saccharomyces cerevisiae, a common spoilage yeast in fruit and vegetable products.
NIU Liyuan, SUN Xiaocheng, LIU Jingfei, WU Zihao, BAI Yanhong, ZHANG Zhijian
doaj   +1 more source

Luttinger liquid in superlattice structures: atomic gases, quantum dots and the classical Ising chain

, 2010
We study physical properties of a Luttinger liquid in a superlattice which is characterized by alternating two tunneling parameters. Employing the Bosonization approach, we describe the corresponding Hubbard model by the equivalent Tomonoga-Luttinger ...
Bhattacherjee, Aranya B, Jha, Pradip, Kumar, Tarun, ManMohan   +3 more
core   +1 more source

Monitoring cold chain logistics by means of RFID. [PDF]

, 2010
Every day, millions of tons of temperature sensitive goods are produced, transported, stored or distributed worldwide. For all these products the control of temperature is essential.
Lunadei, Loredana, Ruiz García, Luis
core   +3 more sources

BlockColdChain: Vaccine Cold Chain Blockchain

, 2023
In this paper, we propose a blockchain-based cold chain technology for vaccine cooling track. The COVID-19 pandemic has caused the death of millions of people. An important step towards ending the pandemic is vaccination. Vaccines must be kept under control temperature during the whole process, from fabrication to the hands of the health professionals ...
Ronan Dutra Mendonça, Otávio S. Gomes, Luiz Filipe M. Vieira, Marcos A. M. Vieira, Alex Borges Vieira, José Augusto Miranda Nacif   +5 more
openaire   +2 more sources

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Low-Temperature and High-Pressure Induced Swelling of a Hydrophobic Polymer-Chain in Aqueous Solution

, 2005
We report molecular dynamics simulations of a hydrophobic polymer-chain in aqueous solution between $260 {K}$ and $420 {K}$ at pressures of $1 {bar}$, $3000 {bar}$, and $4500 {bar}$.
Alfons Geiger, Berendsen, Blokzijl, Brandts, Daggett, De Los Rios, De Los Rios, Dietmar Paschek, Essmann, Flyvbjerg, Forsman, Geiger, Ghosh, Ghosh, Ghosh, Ghosh, Hawley, Herberhold, Herberhold, Hoover, Huang, Hummer, Lindahl, Lüdemann, Lüdemann, Mahoney, Marqués, Miyamoto, Moghaddam, Muller, Naghibi, Neumann, Nicolini, Nosé, Nosé, Pangali, Panick, Parrinello, Paschek, Paschek, Payne, Pearlman, Peng, Pratt, Privalov, Privalov, Ravindra, Rein ten Wolde, Rettich, Rick, Rick, Rick, Roberts, Roberts, Royer, Ryckaert, Sascha Nonn, Shimizu, Shimizu, Shimizu, Silva, Silva, Silverstein, Skipper, Smeller, Smith, Smith, Southall, Wilhelm, Zichi, Zipp   +70 more
core   +1 more source