Results 81 to 90 of about 2,685,039 (301)

Cold chain management and vaccines

, 2020
Pharmacists play a vital role in the distribution, dispensing andadministration of life saving vaccines. A vaccine is a fragile, biological product that may contain live attenuated, modified, toxoid or killed microorganisms, which when administered into ...
Bushell, Mary; id_orcid
core   +2 more sources

TRPML1 agonist ML‐SA5 attenuates pulmonary fibroblast activation by suppressing mTOR and restoring autophagic flux

FEBS Open Bio, EarlyView.
TGF‐β1 stimulation downregulates lysosomal channel TRPML1 in pulmonary fibroblasts. The TRPML1 agonist ML‐SA5 suppressed fibroblast‐to‐myofibroblast activation and collagen production. Mechanistically, ML‐SA5 inhibited mTOR phosphorylation, restored autophagic flux, and its effects were enhanced by rapamycin (mTOR inhibitor) and reversed by MHY1485 ...
Jiatong Yao, Xiaoting Kang, Lulu Meng, Shaoxuan Zhang, Qiujie Li, Jinyu Zhou, Mengyue Xue, Chu Li, Hua Zhu, Pengzhou Hang, Jing Zhao   +10 more
wiley   +1 more source

Effects of the Short-term Temporary Rearing of Micropterus salmoides on Gallic Acid on Its Oxidative Stress Level, Muscle Quality, and Storage Quality

Shipin gongye ke-ji
To explore an efficient and low-cost temporary rearing method from the perspective of the quality assurance of raw materials, we investigated the effects of the temporary rearing of Micropterus salmoides on gallic acid on its oxidative stress level ...
Yiwen WU, Chenxin WANG, Yuting XIA, Ao HU, Lang CHEN, Xiaojia GUO, Wenjin WU, Liu SHI, Tao YIN, Guangquan XIONG, Lan WANG, Sheng CHEN   +11 more
doaj   +1 more source

Multi-State Logging Freeze Detection Passive RFID Tags [PDF]

, 2014
In this work the design and measurement of a passive UHF RFID smart tag suitable for monitoring and recording critical temperature violations in cold chain management are presented.
Ziai, M. Ali, John C. Batchelor, M. Ali Ziai, Batchelor, John C.   +3 more
core   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Evaluation of Dried Plasma Spot‐Based Quantification of Glial Fibrillary Acidic Protein as a Disease‐Associated Biomarker in Neuromyelitis Optica Spectrum Disorder

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate the diagnostic accuracy of glial fibrillary acidic protein (GFAP) measured in dried plasma spots versus conventional plasma‐ and serum‐GFAP testing for assessment of disease severity in aquaporin‐4 immunoglobulin G–positive neuromyelitis optica spectrum disorder (AQP4‐IgG+ NMOSD).
Felix Wohlrab, Evelyn Alvarez, Roua Hamdi, Bingqing Zhang, Hayeun Ji, Niyati Jhaveri, Patrick Schindler, Pedro Sanchez, Pia S. Sperber, Tanja Schmitz‐Hübsch, Frederike C. Oertel, Nisa Vorasoot, Najib Kissani, Falko Böhringer, Jens Kuhle, Anne‐Katrin Pröbstel, Xiao‐Jun Ma, Péter Körtvelyessy, Patrick Waters, Friedemann Paul   +19 more
wiley   +1 more source

Effects of plasma-activated water on structural and functional properties of PSE-like chicken protein isolate

Current Research in Food Science
Pale, soft and exudative (PSE)-like chicken meat is rich in high-quality proteins, however, due to the properties of PSE-like meat, the functional characteristics of PSE-like chicken meat protein isolate (PPI) are affected.
Ke Li, Yanfang Zhou, Chenyan Zhu, Manting Du, Bo Chen, Dianbo Zhao, Yanhong Bai   +6 more
doaj   +1 more source

Current Status and Challenges in Data Collection for Aerospace Coatings Deposited by Plasma Spraying

Advanced Engineering Materials, EarlyView.
An innovative approach has been integrated into the GRENAT project to optimize plasma spraying and coating performance. Raw materials are accelerated and melted in the plasma generated by torches, creating coatings. Monitoring sensors collect process data which are combined with ex situ characterization data.
Lila Randriamananjara, Vincent Rat, Quentin Dubreuil, Patrice Valorge, Simon Goutier, Alain Denoirjean, Olivier Messe, Céline Ruelle, Jean‐Philippe Poli   +8 more
wiley   +1 more source

Research on the Influence of Moisture State, Microscopic Morphology and Physical Properties of the Resting Dough

Shipin gongye ke-ji
To study the effect of resting on the quality of frozen dough, the changes in the moisture state of the dough during the resting process (0, 30, 60, 90, 120 min), the moisture distribution of dough and their effects on ice crystal distribution ...
Yanyan ZHANG, Jie ZHANG, Jing ZHANG, Pu ZHANG, Xingli LIU, Hua ZHANG   +5 more
doaj   +1 more source

Supply Chain in Relation to Tourism and Crowd Management

, 2022
Proceedings of the 40th International Business Information Management Association Conference, Seville, Spain, November 23-24, 2022.The tourism industry is one of the fastest growing economic sectors in the world, and the developments in the industry are ...
Almaktoom, Abdulaziz, Shami, Atheer
core