Results 81 to 90 of about 4,790,269 (352)
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
We study physical properties of a Luttinger liquid in a superlattice which is characterized by alternating two tunneling parameters. Employing the Bosonization approach, we describe the corresponding Hubbard model by the equivalent Tomonoga-Luttinger ...
Bhattacherjee, Aranya B +3 more
core +1 more source
The Incidence of Low-Metallicity Lyman-Limit Systems at z~3.5: Implications for the Cold-Flow Hypothesis of Baryonic Accretion [PDF]
Cold accretion is a primary growth mechanism of simulated galaxies, yet observational evidence of "cold flows" at redshifts where they should be most efficient ($z=2$-4) is scarce.
Cooksey, Kathy L. +4 more
core +2 more sources
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
Purpose – The purpose of this paper is to analyze how far technology and information enable, facilitate or support the planning and implementation decisions in humanitarian vaccine cold chains for vaccination campaigns. The authors specifically focus on three emerging technologies that have the potential to create more flexible conditions in the field,
Tina Comes +2 more
openaire +1 more source
Evolution of the Relativistic Plasmoid-Chain in the Poynting-Dominated Plasma
In this paper, we investigate the evolution of the plasmoid-chain in a Poynting-dominated plasma. We model the relativistic current sheet with cold background plasma using the relativistic resistive magnetohydrodynamic approximation, and solve its ...
Takamoto, Makoto
core +1 more source
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
Fresh fruits are inherently prone to postharvest deterioration due to loss of moisture, respiration, mechanical damage, and microbial decay, making quality preservation a persistent challenge across fresh fruit supply chains.
Siphumle Owen Jama +4 more
doaj +1 more source
Variation in the prevalence of enteropathogenic Yersinia in slaughter pigs from Belgium, Italy, and Spain [PDF]
Tonsils of 829 fattening pigs originating from Belgium (n = 201), Italy (n = 428), and Spain (n 200) were collected between 2005 and 2007 to study the prevalence of enteropathogenic Yersinia in slaughter pigs.
Fredriksson-Ahomaa, Maria +5 more
core +1 more source
DDX3X induces mesenchymal transition of endothelial cells by disrupting BMPR2 signaling
Elevated DDX3X expression led to downregulation of BMPR2, a key regulator of endothelial homeostasis and function. Our co‐immunoprecipitation assays further demonstrated a molecular interaction between DDX3X and BMPR2. Notably, DDX3X promoted lysosomal degradation of BMPR2, thereby impairing its downstream signaling and facilitating endothelial‐to ...
Yu Zhang +7 more
wiley +1 more source

