Results 101 to 110 of about 860,994 (301)
Zinc Lozenges: Cold Cure or Candy? Solution Chemistry Determinations [PDF]
Bioscience Reports, 2004 Common colds were shortened by 7 days in a 1984 clinical trial using zinc gluconate throat lozenges each 2 h. Between then and 2004, 10 other double-blind, placebo-controlled clinical trials showed widely varying results. This re-analysis of these trials presents solution chemistry methods to elucidate differences in efficacy. Statistically significant
openaire +2 more sources
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Molecules and Ions at Very Low Temperatures
CHIMIA, 2009 The generation and study of 'cold' gas-phase molecules characterised by very low translational temperatures Ttrans ? 1 K is an upcoming field of research in physical chemistry which has received considerable attention over the past years.
Stefan Willitsch
doaj +1 more source
FEBS Open Bio, EarlyView.ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand +2 more
wiley +1 more source
Anchorage‐independent and faster growth in clonal population from UV‐irradiated NER‐deficient cells
FEBS Open Bio, EarlyView.UV‐irradiated cells expressing a DDB2 mutant protein unable to interact with PCNA (DDB2PCNA‐) form clones able to grow without anchorage. Different experimental approaches reveal heterogeneity in cell cycle regulation and drug response within these clones, emphasizing the crucial role of the DDB2‐PCNA interaction in preventing cellular transformation ...
Paola Perucca +6 more
wiley +1 more source
Nanomaterials6-thioguanine (6-TG) is an antimetabolite drug of purine structure, approved by the FDA for the treatment of acute myeloid lesukemia, and it is of interest in treating other diseases.
Sheriff Umar +4 more
doaj +1 more source
Molecular Identifications in Experiments with Astronomical Ice Analogues: New Data, Old Strategies, and the N2 + Acetone System [PDF]
A recent publication on the radiation chemistry and IR spectroscopy of N2 plus acetone ices is used to illustrate some of the difficulties encountered in the study of astronomical ice analogues.
Gerakines, Perry A., Hudson, Reggie L.
core +1 more source
Fast and efficient transport of large ion clouds
, 2015 The manipulation of trapped charged particles by electric fields is an accurate, robust and reliable technique for many applications or experiments in high-precision spectroscopy.
Champenois, Caroline +5 more
core +4 more sources
FEBS Open Bio, EarlyView.14‐day casting‐induced immobilization reduced gastrocnemius muscle mass and increased non‐heme iron and ferritin heavy chain levels. Despite iron accumulation, transferrin receptor 1 and iron regulatory protein 2 were paradoxically upregulated. Lipid peroxidation was elevated without compensatory antioxidant responses.
Haruka Yokogawa +2 more
wiley +1 more source
Nano Biomedicine and Engineering, 2016 We present the synthesis, characterization, biological and sensing applications of a Schiff base, (E)-3-((5-bromo-2-hydroxy-3-methoxycyclohexa-1, 3-dienyl)methyleneamino)-6-(hydroxymethyl)-tetrahydro-2H-pyran-2,4,5-triol.
Solomon Tadesse +4 more
doaj +1 more source