Results 11 to 20 of about 3,995 (211)

Study the toxic effect of non-bound colicins extracted from Escherichia coil on transplanted Murine adenocarcinoma (AM3)

مجلة مركز بحوث التقنيات الاحيائية, 2009
Four types of non-bound colicins (H5, H9, H13, H19) extracted from intestinal normal flora E.coli isolated from apparently healthy people’s stool. Then cytotoxic effect of colicins on transplanted murine adenocarcinoma (AM3) was studied.
Hind Hussein Obaid, Nahiy Yousif Yaseen, Rajwa Hassan Essa   +2 more
doaj   +3 more sources

Bacteriocins as a Promising Antimicrobial Strategy Against Multidrug‐Resistant Pathogens: Mechanisms of Action, Applications in Human and Animal Health, and the Food Industry [PDF]

BioMed Research International, Volume 2026, Issue 1, 2026.
The global rise of antimicrobial resistance has significantly increased the difficulty treating infectious agents, creating an urgent need for alternative therapeutic strategies. In this context, bacteriocins have emerged as a promising solution, offering a potential alternative to conventional antibacterial therapies.
Abdo Megra Geda, Aregash Wendimu Tumebo, Solomon Lulie Abey, Gashaw Enbiyale Kasse, Abraham Belete Temesgen, Zerihun Getie Wassie, Baisakhi Banerjee   +6 more
wiley   +2 more sources

Isolation and characterization of bacteriocin-producing E. coli isolates from a poultry slaughterhouse, and cell-free production and evaluation of native and engineered bacteriocins [PDF]

Poultry Science
Antimicrobial resistance (AMR) is a growing public health threat, particularly in food animal production. Poultry acts as a major reservoir for AMR dissemination, underscoring the need for sustainable alternatives to antibiotics.
Irene Lafuente, Ester Sevillano, Nuria Peña, Luis M. Cintas, Estefanía Muñoz-Atienza, Pablo E. Hernández, Juan Borrero   +6 more
doaj   +2 more sources

Salt bridge disruption in colicin Ib channel-forming domain enhances membrane translocation and bactericidal activity [PDF]

Journal of Structural Biology: X
Pore-forming colicins are bacteriocins produced by Escherichia coli to kill competing bacterial strains by forming ion-permeable channels in the inner membrane of target cells, leading to membrane depolarization, ion leakage, and ultimately cell death ...
Jie Yang, Pei-Fen Liu, Wei-Jie Wang, Shih-Chun Yang, Chia-Liang Lin, Yung-Chuan Liu, Che-An Tsai, Jiann-Hwa Chen, Nien-Jen Hu   +8 more
doaj   +2 more sources

Binding Free Energy Analysis of Colicin D, E3 and E8 to Their Respective Cognate Immunity Proteins Using Computational Simulations [PDF]

Molecules
Colicins are antimicrobial proteins produced by bacteria for the purpose of destroying neighboring bacteria. Colicin activity is neutralized by a specific cognate immunity protein in order to protect the host.
Mahesh Koirala, Clifton K. Fagerquist
doaj   +2 more sources

Shigella sonnei utilises colicins during inter-bacterial competition. [PDF]

Microbiology (Reading)
International audienceThe mammalian colon is one of the most densely populated habitats currently recognised, with 10 11 –10 13 commensal bacteria per gram of colonic contents.
Leung PB, Matanza XM, Roche B, Ha KP, Cheung HC, Appleyard S, Collins T, Flanagan O, Marteyn BS, Clements A, Clements A.   +10 more
europepmc   +2 more sources

Mannose-Presenting “Glyco-Colicins” Convert the Bacterial Cell Surface into a Multivalent Adsorption Site for Adherent Bacteria [PDF]

JACS Au
Biofilm formation is integral to the pathogenesis of numerous adherent bacteria and contributes to antimicrobial resistance (AMR). The rising threat of AMR means the need to develop novel non-bactericidal anti-adhesion approaches against such bacteria is
Natasha E. Hatton, Joe Nabarro, Nicholas D. J. Yates, Alison Parkin, Laurence G. Wilson, Christoph G. Baumann, Martin A. Fascione   +6 more
doaj   +3 more sources

Convergence of plasmid-driven virulence and antibiotic resistance in Escherichia coli [PDF]

Nature Communications
Plasmids are major vehicles for the spread of antibiotic resistance genes. Some plasmids additionally carry virulence genes that enhance host pathogenicity.
Zheng Jie Lian, Nguyen Thi Khanh Nhu, Chitra Ravi, Chyden Chang, Irene Martinez-Roman, Minh-Duy Phan, Mark A. Schembri   +6 more
doaj   +2 more sources

Colicins and T6SS-based competition systems enhance enterotoxigenic E. coli (ETEC) competitiveness [PDF]

Gut Microbes
Diarrheal diseases are still a significant problem for humankind, causing approximately half a million deaths annually. To cause diarrhea, enteric bacterial pathogens must first colonize the gut, which is a niche occupied by the normal bacterial ...
Jonas Kjellin, Danna Lee, Hans Steinsland, Rachel Dwane, Oda Barth Vedoy, Kurt Hanevik, Sanna Koskiniemi   +6 more
doaj   +2 more sources

Comparative genome analysis of Pseudomonas chlororaphis strains reveals biosynthetic diversity underlying plant growth promotion and soil health improvement [PDF]

BMC Genomics
Background The growing need for sustainable farming methods has led to increased efforts to understand plant-beneficial microbes that can serve as alternatives to chemical fertilizers and pesticides.
Izzah Shahid, Lucas Gabriel Castellani, Abdul Aziz Eida, Emrah Nikerel, Deeba Noreen Baig, Qurat ul Ain Hanif, Maged M. Saad, Kauser Abdulla Malik, Samina Mehnaz   +8 more
doaj   +2 more sources