Results 81 to 90 of about 33,804 (189)

Colistin-daptomycin, colistin-linezolid, colistin-vancomycin combination effects on colistin in multi-resistant acinetobacter baumannii strains

Medical Science and Discovery, 2018
Objective: The most important problem in the treatment of nosocomial Acinetobacter baumannii (A. baumannii) infections which is increasingly seen in recent years is that almost all strains are resistant to many antibiotics, including carbapenems, and that the extinction of antibiotic options to be used in treatment.
openaire   +3 more sources

Inhibition of Staphylococcus aureus Biofilm Formation by Plumbagin Combined With Ceftazidime and Cefazolin

eFood, Volume 7, Issue 4, August 2026.
Plumbagin can be potentially used in combination with antibiotics, as a safer, and effective agent solution against biofilms formed by Staphylococcus aureus in the healthcare, and food industry. ABSTRACT Biofilm‐forming Staphylococcus aureus is the major cause several foodborne diseases, and pose a serious challenge in the healthcare, and food industry.
Borel Ndezo Bisso, Humera Jahan, Akim Socohou, Mamadou Sawadogo, Jean Paul Dzoyem, M. Iqbal Choudhary   +5 more
wiley   +1 more source

Seasonal Restructuring of Microbial Communities and Resistomes in the Shitalakshya River, Bangladesh Revealed by Shotgun Metagenomics

MicrobiologyOpen, Volume 15, Issue 4, August 2026.
Dry‐season pollutant concentration drives microbial restructuring in Bangladesh's Shitalakshya River, shifting communities from Myroides to stress‐tolerant genera while enriching metal resistance genes and efflux pumps, revealing non‐antibiotic co‐selection as a key driver of antimicrobial resistance in urban waters.
Muhammad Ehteshamul Haque, Md. Shaminur Rahman, Munawar Sultana, Anowara Begum   +3 more
wiley   +1 more source

Colistin Resistance Development Following Colistin-Meropenem Combination Therapy Versus Colistin Monotherapy in Patients With Infections Caused by Carbapenem-Resistant Organisms

Clinical Infectious Diseases, 2019
Abstract Background We evaluated whether carbapenem-colistin combination therapy reduces the emergence of colistin resistance, compared to colistin monotherapy, when given to patients with infections due to carbapenem-resistant Gram-negative organisms.
Yaakov Dickstein, Jonathan Lellouche, David Schwartz, Amir Nutman, Nadya Rakovitsky, Yael Dishon Benattar, Sergey Altunin, Mariano Bernardo, Domenico Iossa, Emanuele Durante-Mangoni, Anastasia Antoniadou, Anna Skiada, Ioannis Deliolanis, George L Daikos, Vered Daitch, Dafna Yahav, Leonard Leibovici, Viktor Rognås, Lena E Friberg, Johan W Mouton, Mical Paul, Yehuda Carmeli, Mical Paul, Yael Dishon Benattar, Yaakov Dickstein, Roni Bitterman, Hiba Zayyad, Fidi Koppel, Yael Zak-Doron, Sergey Altunin, Nizar Andria, Ami Neuberger, Anat Stern, Neta Petersiel, Marina Raines, Amir Karban, Leonard Leibovici, Dafna Yahav, Noa Eliakim-Raz, Oren Zusman, Michal Elbaz, Heyam Atamna, Vered Daitch, Tanya Babich, Yehuda Carmeli, Amir Nutman, Amos Adler, Inbar Levi, George L Daikos, Anna Skiada, Ioannis Deliolanis, Ioannis Pavleas, Anastasia Antoniadou, Antigoni Kotsaki, Emanuele Durante-Mangoni, Roberto Andini, Domenico Iossa, Mariano Bernardo, Giusi Cavezza, Lorenzo Bertolino, Giuseppe Giuffre, Roberto Giurazza, Susanna Cuccurullo, Maria Galdo, Patrizia Murino, Adriano Cristinziano, Antonio Corcione, Rosa Zampino, Pia Clara Pafundi, Johan Mouton, Lena Friberg, Anders Kristoffersson, Ursula Theuretzbacher   +72 more
openaire   +3 more sources

Detection of OXA‐23 Among Carbapenem‐Resistant Acinetobacter baumannii Isolated From Intensive Care Units of a Tertiary Care Hospital in Pakistan

MicrobiologyOpen, Volume 15, Issue 4, August 2026.
Graphical Abstract of the Experimental Workflow for CRAB Isolate Characterization. ABSTRACT Carbapenem‐resistant Acinetobacter baumannii (CRAB) has been designated a top‐priority critical pathogen by the World Health Organization, and the CDC has also classified it as a serious and immediate public health threat. The Cross‐sectional study was conducted
Hafsa Waseem, Ihsan Ullah, Shahzad Ahmad, Irfan Ali Mirza, Benish Aleem, Shazia Iqbal   +5 more
wiley   +1 more source

Comparative in vivo evaluation of colistin resistance determinants in Escherichia coli clone ST131Research in context

EBioMedicine
Summary: Background: Colistin is a last-resort antimicrobial for multidrug-resistant (MDR) Gram-negative infections. Health risks associated with colistin resistance are commonly inferred from resistance phenotypes, despite limited in vivo evidence ...
Toyotaka Sato, Soh Yamamoto, Jirachaya Toyting-Hiraishi, Mana Tohyama, Masaru Usui, Hiharu Inoue, Noriko Ogasawara, Yoshinori Ikenaka, Wataru Hayashi, Hidetaka Kosako, Masato Suzuki, Noriyuki Nagano, Takayuki Wada, Chie Nakajima, Yasuhiko Suzuki, Motohiro Horiuchi, Satoshi Takahashi, Shin-ichi Yokota, Yutaka Tamura   +18 more
doaj   +1 more source

Longitudinal Molecular Epidemiology and Genomic Surveillance of Carbapenem‐Resistant Klebsiella pneumoniae in the Gut of Healthy Individuals in China

MedComm, Volume 7, Issue 8, August 2026.
Using 16,040 stool samples from healthy individuals across 30 Chinese provinces (2016–2024), we performed longitudinal genomic surveillance of carbapenem‑resistant Klebsiella pneumoniae (CRKP) colonizing the gut. We reveal rising community CRKP prevalence, especially in southern China, a shift from blaKPC‐2 to plasmid‑borne blaNDM‐5 on IncHI2/IncHI2A ...
Zelin Yan, Yan Li, Yi Sun, Qiaoling Sun, Congcong Liu, Yanyan Zhang, Yuchen Wu, Hongwei Zhou, Shangshang Qin, Gongxiang Chen, Ruichao Li, Rong Zhang   +11 more
wiley   +1 more source

Adaptive colistin resistance dynamics in mcr-9-positive and -negative Enterobacterales following low-level colistin exposure

Microbiology Spectrum
The mcr-9 gene has been reported across different sources and was recognized as a potential contributor to increased minimum inhibitory concentrations after colistin exposure. This study aimed to determine the prevalence of intestinal carriage of the mcr-
Eva Smelikova, Marie Brajerova, Jan Tkadlec, Pavel Drevinek, Marcela Krutova   +4 more
doaj   +1 more source

Vibrio Community Structure Shapes the Diversity of Carbenicillin‐Hydrolysing Class A β‐Lactamase Circulating in European Coastal Environments

Environmental Microbiology, Volume 28, Issue 8, August 2026.
Vibrio communities shape carbenicillinase diversity in European coasts. Sediments serve as reservoirs of antibiotic‐resistant Vibrio alginolyticus, which can move into the water column and accumulate in bivalves. This spreads β‐lactamase resistance and raises human exposure risks to antibiotic‐resistant pathogenic Vibrio, especially as higher seawater ...
Berenice Reggiardo, Jamal Saad, Marie‐Agnès Travers, Yannick Labreuche, David Goudenège, Eve Toulza, Coralie Broquard, Karl B. Andree, Julia Mougin, Nicolas Argenta, Gaëlle Courtay, Juliette Pouzadoux, Océane Romatif, Audrey Caro, Dolors Furones, Luigi Vezzulli, Gianluca Corno, Andrea Di Cesare, Ignasi Gairin, Bruno Petton, K. Mathias Wegner, Caroline Montagnani, Viviane Boulo, Delphine Destoumieux‐Garzón   +23 more
wiley   +1 more source

Resistance to Colistin in Klebsiella pneumoniae: A 4.0 Strain?

Infectious Disease Reports, 2017
The global rise of multidrug-resistant gram-negative bacteria represents an increasing threat to patient safety. From the first observation of a carbapenem-resistant gramnegative bacteria a global spread of extendedspectrum beta-lactamases and carbapenemases producing Klebsiella pneumoniae has been observed. Treatment options for multidrug-resistant K.
Guido Granata, Nicola Petrosillo
openaire   +4 more sources