Results 111 to 120 of about 199,144 (206)

Effects of Lactobacillus fermentum GKF3 on Reducing Smoking and Brain Neurotransmitter Levels: Findings From Animal and Human Studies

open access: yesFood Frontiers, EarlyView.
1.Developing food‐grade probiotic strains with smoking reduction benefits presents a safer and more holistic health strategy. 2.An animal study demonstrated that L. fermentum GKF3 gavage elevated brain dopamine and serotonin levels. 3.A randomized controlled trial showed that L.
You‐Shan Tsai   +6 more
wiley   +1 more source

Deletion of epithelial HKDC1 decelerates cellular proliferation and impairs mitochondrial function of tumorous epithelial cells thereby protecting from intestinal carcinogenesis

open access: yes
Cancer Communications, EarlyView.
Lea Järke   +15 more
wiley   +1 more source

Alfalfa Flavonoids Mitigate Salmonella‐Induced Colitis via the Keap1‐Nrf2 and TLR4/NF‐κB/COX‐2 Pathways

open access: yesFood Frontiers, EarlyView.
Alfalfa flavonoids (AF) protected against Salmonella‐induced colitis by reducing inflammation and oxidative stress. AF inhibited the TLR4/IκB/NF‐κB/COX‐2 pathway and NLRP3 inflammasome, lowering pro‐inflammatory cytokines, while activating Keap1‐Nrf2 to boost antioxidants (e.g., HO‐1, NQO1, SOD, GPx), decreasing ROS‐driven oxidative stress.
Xiaoli Qin   +11 more
wiley   +1 more source

Bioactive Polysaccharides Targeting Gut Microbiota to Modulate Host Health: A Gear Effect Theory

open access: yesFood Frontiers, EarlyView.
The “Gear Effect” mechanism of bioactive polysaccharides driving gut microbiota to modulate host health. ABSTRACT Bioactive polysaccharides are macromolecular polymers with broad biological activities. Recent evidence has highlighted their role in modulating host health primarily through interactions with gut microbiota.
Yonggan Sun   +3 more
wiley   +1 more source

Pathogenic Escherichia coli Virulome in Top Soil Improvers and Irrigation Waters Devoted to Leafy Vegetable Production: Hazard Assessment From a Case Study in Italy

open access: yesFood Safety and Health, EarlyView.
Escherichia coli pathotype virulotyping to assess if combined top soil improver and water inputs would potentially lead to hybrid strains with shuffled virulence features in ready‐to‐eat vegetables. This is to support the transition toward safe and sustainable food production systems.
Giorgia Barbieri   +9 more
wiley   +1 more source

Phytochemical Contents and Bioactive Compounds in Widely Consumed Cereals, Legumes, and Vegetables in Abruzzo Region, Italy: A Critical Review

open access: yesFood Safety and Health, EarlyView.
This review aims to collect and identify cereals, legumes, and vegetables mostly consumed in the Abruzzo region from 2020 till now, pointing attention to their biological effects. ABSTRACT The Abruzzo region boasts a wide range of typical food products including cereals, legumes, and vegetables. In this context, they take part in the Mediterranean diet,
Giulia Gentile   +3 more
wiley   +1 more source

Combined Tumor Infiltrating Lymphocytes and PD‐L1 Status in Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma

open access: yesHead &Neck, EarlyView.
ABSTRACT Objectives To determine if the assessment of CD8+ tumor‐infiltrating lymphocytes (TILs) adds prognostic information to the PD‐L1 combined positive score (CPS) in recurrent/metastatic (R/M) head and neck squamous cell carcinoma (HNSCC). Methods A retrospective case series was performed of 77 patients with R/M HNSCC between 2003 and 2019.
Catherine T. Haring   +8 more
wiley   +1 more source

The causal relationship between systemic lupus erythematosus and juvenile myoclonic epilepsy: A Mendelian randomization study and mediation analysis

open access: yesIbrain, Volume 11, Issue 1, Page 98-105, Spring 2025.
Mendelian randomization (MR) studies were conducted using the inverse‐variance weighted (IVW) method, MR‐Egger and weighted median on juvenile myoclonic epilepsy (JME), and systemic lupus erythematosus (SLE) data from the Integrative Epidemiology Unit (IEU) Open genome‐wide association study (GWAS) database and the International League Against Epilepsy
Sirui Chen   +10 more
wiley   +1 more source

TNF signature in advanced melanoma patients treated with immune checkpoint inhibitors: Results from the MELANFα clinical study

open access: yesInternational Journal of Cancer, EarlyView.
What's New? Tumor necrosis factor (TNF) can promote tumor resistance to immune checkpoint inhibitors (ICIs), which are now the standard treatment for advanced melanoma patients. Here, in an advanced melanoma patient cohort, TNF was investigated for a possible predictive relationship with ICI response. Assessments show that after 12 weeks of ICI therapy,
Mathieu Virazels   +18 more
wiley   +1 more source

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