Results 11 to 20 of about 672,024 (402)

Landscape of inflammatory bowel disease in Singapore [PDF]

Intestinal Research, 2022
Inflammatory bowel disease (IBD), primarily Crohn’s disease and ulcerative colitis, had been widely recognized to affect the Western population. However, the notable rise in prevalence of IBD in Asia, including Singapore, had garnered much attention to ...
Daren Low, Nidhi Swarup, Toshiyuki Okada, Emiko Mizoguchi   +3 more
doaj   +1 more source

Zinc Protoporphyrin Is a Reliable Marker of Functional Iron Deficiency in Patients with Inflammatory Bowel Disease

Diagnostics, 2021
Iron deficiency (ID) is a common manifestation of inflammatory bowel disease (IBD), arising primarily due to chronic inflammation and/or blood loss. There is no gold standard for ID diagnosis, which is often complicated by concomitant inflammation.
Eleni Leventi, Aysegül Aksan, Carl Thomas Nebe, Jürgen Stein, Karima Farrag   +4 more
doaj   +1 more source

Flipside of the Coin: Iron Deficiency and Colorectal Cancer

Frontiers in Immunology, 2021
Iron deficiency, with or without anemia, is the most frequent hematological manifestation in individuals with cancer, and is especially common in patients with colorectal cancer.
Aysegül Aksan, Aysegül Aksan, Aysegül Aksan, Karima Farrag, Karima Farrag, Sami Aksan, Sami Aksan, Oliver Schroeder, Oliver Schroeder, Jürgen Stein, Jürgen Stein, Jürgen Stein   +11 more
doaj   +1 more source

Gut microbiota from green tea polyphenol-dosed mice improves intestinal epithelial homeostasis and ameliorates experimental colitis

Microbiome, 2021
Background Alteration of the gut microbiota may contribute to the development of inflammatory bowel disease (IBD). Epigallocatechin-3-gallate (EGCG), a major bioactive constituent of green tea, is known to be beneficial in IBD alleviation. However, it is
Zhenhua Wu, Shimeng Huang, Tiantian Li, Na Li, Dandan Han, Bing-Kun Zhang, Z. Xu, Shiyi Zhang, Jiaman Pang, Shilan Wang, Guolong Zhang, Jiangchao Zhao, Junjun Wang   +12 more
semanticscholar   +1 more source

Mannose ameliorates experimental colitis by protecting intestinal barrier integrity

Nature Communications, 2022
Metabolite alteration has been associated with the pathogenesis of inflammatory bowel disease (IBD), including colitis. Mannose, a natural bioactive monosaccharide that is involved in metabolism and synthesis of glycoproteins, exhibits anti-inflammatory ...
Lijun Dong, Jingwen Xie, Youyi Wang, Hongliang Jiang, Kai Chen, Dantong Li, Jing Wang, Yunzhi Liu, Jia He, Jia Zhou, Li-yun Zhang, Xiao Lu, X. Zou, Xiang-Yang Wang, Qingqing Wang, Zhengliang Chen, Daming Zuo   +16 more
semanticscholar   +1 more source

Oral administration of turmeric-derived exosome-like nanovesicles with anti-inflammatory and pro-resolving bioactions for murine colitis therapy

Journal of Nanobiotechnology, 2022
Background Ulcerative colitis (UC) is an inflammatory bowel disease (IBD) characterized by diffuse inflammation of the colonic mucosa and a relapsing and remitting course.
Cui Liu, X. Yan, Yujie Zhang, Mei Yang, Yana Ma, Yuanyuan Zhang, Qiuran Xu, K. Tu, Mingzhen Zhang   +8 more
semanticscholar   +1 more source

Long-term outcomes of infliximab in a real-world multicenter cohort of patients with acute severe ulcerative colitis [PDF]

Intestinal Research, 2021
Background/Aims Infliximab (IFX) has proven effective as rescue therapy in steroid-refractory acute severe ulcerative colitis (ASUC), however, the long-term real-world data are scarce.
Shin Ju Oh, Ga Young Shin, Hosim Soh, Jae Gon Lee, Jong Pil Im, Chang Soo Eun, Kang-Moon Lee, Dong Il Park, Dong Soo Han, Hyo Jong Kim, Chang Kyun Lee   +10 more
doaj   +1 more source

Probiotics (Lactobacillus plantarum HNU082) Supplementation Relieves Ulcerative Colitis by Affecting Intestinal Barrier Functions, Immunity-Related Gene Expression, Gut Microbiota, and Metabolic Pathways in Mice

Microbiology spectrum, 2022
Many studies have focused on the therapeutic effect of probiotics on ulcerative colitis (UC), but few studies have paid attention to the mechanism of probiotics, especially the therapeutic effect.
Yuqing Wu, R. Jha, Ao Li, Huanwei Liu, Zeng Zhang, Chengcheng Zhang, Q. Zhai, Jiachao Zhang   +7 more
semanticscholar   +1 more source

Dimethyl Fumarate Alleviates Dextran Sulfate Sodium-Induced Colitis, through the Activation of Nrf2-Mediated Antioxidant and Anti-inflammatory Pathways. [PDF]

, 2020
Oxidative stress and chronic inflammation play critical roles in the pathogenesis of ulcerative colitis (UC) and inflammatory bowel diseases (IBD). A previous study has demonstrated that dimethyl fumarate (DMF) protects mice from dextran sulfate sodium ...
Farzaneh, Ted, Ichii, Hirohito, Lau, Hien, Li, Shiri, Robles, Lourdes, Stamos, Michael J, Takasu, Chie, Vaziri, Nosratola D, Vo, Kelly   +8 more
core   +2 more sources

Clostridium butyricum and Its Derived Extracellular Vesicles Modulate Gut Homeostasis and Ameliorate Acute Experimental Colitis

Microbiology spectrum, 2022
This study indicated that C. butyricum provided a prevention effect against colitis mice, which involved protection of the intestinal barrier and positively regulating gut microbiota. Furthermore, we confirmed that the gut microbiota and metabolites that
Lingyan Ma, Qichen Shen, W. Lyu, Lu Lv, Wen Wang, Minjie Yu, Hua Yang, Shiyu Tao, Yingping Xiao   +8 more
semanticscholar   +1 more source