Results 11 to 20 of about 302,337 (268)

Recent updates on the basic mechanisms and pathogenesis of inflammatory bowel diseases in experimental animal models [PDF]

Intestinal Research, 2020
The specific pathogenesis underlining inflammatory bowel disease (IBD) is very complicated, and it is further more difficult to clearly explain the pathophysiology of 2 major forms of IBD, Crohn’s disease (CD) and ulcerative colitis (UC), and both ...
Emiko Mizoguchi, Daren Low, Yui Ezaki, Toshiyuki Okada   +3 more
doaj   +1 more source

Safety and Efficacy of Ustekinumab in the Treatment of Crohn Disease: A Systematic Review and Meta-analysis

Journal of Coloproctology, 2022
Background and Aims The present systematic review and meta-analysis was designed to estimate the safety and effectiveness of ustekinumab in the treatment of Crohn disease (CD) in clinical trials and observational studies.
Mohammed Assem Khorshid, Ahmed Cordie, Sherief Abd-Elsalam   +2 more
doaj   +1 more source

SARS-CoV-2 vaccination in inflammatory bowel disease patients is not associated with flares: a retrospective single-centre Swiss study

Annals of Medicine
Introduction Vaccination hesitancy is an important barrier to vaccination among IBD patients. The development of adverse events is the main concern reported.
Laura N. Rossier, Natalie P. Décosterd, Christoph B. Matter, Dominic A. Staudenmann, André Moser, Bernhard Egger, Frank W. Seibold   +6 more
doaj   +1 more source

Medical trauma in young adults with inflammatory bowel disease: The role of trauma-informed care

Health Care Transitions
Medical trauma is a profound concern for those with chronic conditions like inflammatory bowel disease (IBD), especially young adults. This trauma, arising from both the disease itself and necessary medical interventions, manifests as an accumulation of ...
Amy K. Bugwadia, Sydney Reed, Mara Shapiro, Sneha Dave, Nikhil Jayswal, David Kohler, Laurie Keefer   +6 more
doaj   +1 more source

An Etiologic Profile of Anemia in 405 Geriatric Patients

Anemia, 2014
Background. Anemia is a common condition in the elderly and a significant risk factor for increased morbidity and mortality, reducing not only functional capacity and mobility but also quality of life.
Tabea Geisel, Julia Martin, Bettina Schulze, Roland Schaefer, Matthias Bach, Garth Virgin, Jürgen Stein   +6 more
doaj   +1 more source

Efficacy and Safety of Intravenous Ferric Carboxymaltose in Geriatric Inpatients at a German Tertiary University Teaching Hospital: A Retrospective Observational Cohort Study of Clinical Practice

Anemia, 2015
Current iron supplementation practice in geriatric patients is erratic and lacks evidence-based recommendations. Despite potential benefits in this population, intravenous iron supplementation is often withheld due to concerns regarding pharmacy expense,
Matthias Bach, Tabea Geisel, Julia Martin, Bettina Schulze, Roland Schaefer, Garth Virgin, Juergen Stein   +6 more
doaj   +1 more source

Temporal Trends in and Associations With Nonsteroidal Anti‐inflammatory Drug Prescription in Adult and Pediatric Patients With Inflammatory Bowel Disease

Arthritis Care &Research, EarlyView.
Objective Recent inflammatory bowel disease (IBD) treatment guidelines have recommended against nonsteroidal anti‐inflammatory drug (NSAID) use despite prevalent musculoskeletal symptoms and opioid overuse in this population. Given the discordance between changing national guidelines and potential clinical utility, we sought to assess national temporal
Adam S. Mayer, Rui Xiao, Andrew Grossman, Meenakshi Bewtra, Michael D. George, Pamela F. Weiss   +5 more
wiley   +1 more source

Impaired Long-Term Quantitative Cellular Response to SARS-CoV-2 Vaccine in Thiopurine-Treated IBD Patients

Cells
Background: Studies investigating the long-term cellular immune response to SARS-CoV-2 mRNA vaccines in patients with inflammatory bowel disease (IBD) remain limited, particularly among those receiving immunosuppressive therapy. Methods: We prospectively
Luis Mayorga Ayala, Claudia Herrera-deGuise, Juliana Esperalba, Xavier Martinez-Gomez, Elena Céspedes Martinez, Xavier Serra Ruiz, Virginia Robles, Ernesto Lastiri, Zahira Perez, Elena Oller, Candela Fernandez-Naval, Mónica Martinez-Gallo, Francesc Casellas, Natalia Borruel   +13 more
doaj   +1 more source

The Establishment of a National Tissue Bank for Inflammatory Bowel Disease Research in Canada

Canadian Journal of Gastroenterology, 2003
The Crohn’s and Colitis Foundation of Canada (CCFC) has established a national bank for tissue, serum and blood from patients with inflammatory bowel disease (IBD).
Stephen M Collins, Kevin McHugh, Ken Croitoru, Micheal Howorth   +3 more
doaj   +1 more source

Helminth Interactions with Bacteria in the Host Gut Are Essential for Its Immunomodulatory Effect

Microorganisms, 2021
Colonization by the benign tapeworm, Hymenolepis diminuta, has been associated with a reduction in intestinal inflammation and changes in bacterial microbiota. However, the role of microbiota in the tapeworm anti-inflammatory effect is not yet clear, and
Milan Jirků, Zuzana Lhotská, Lucia Frgelecová, Oldřiška Kadlecová, Klára Judita Petrželková, Evan Morien, Kateřina Jirků-Pomajbíková   +6 more
doaj   +1 more source