Results 61 to 70 of about 1,136,104 (305)

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Task Management to enhance Collaborative Work

Journal of Science and Research, 2016
The collaborative work in the classroom is not something new, the really new is the Management of tasks that enhance the collaborative work that is supported in Web 2.0, considered as an appendix of the web, the same that is based on communities Of users
Luis Amilcar Olvera Vera, Denisse Salcedo, Joffre Loor Rosales   +2 more
doaj   +1 more source

COMPUTER-ASSISTED COLLABORATIVE WRITING AND STUDENTS’ PERCEPTIONS OF GOOGLE DOCS AND WIKIS: A REVIEW PAPER

Language Literacy: Journal of Linguistics, Literature, and Language Teaching, 2020
Computer-assisted collaborative writing has been gradually employed in L2 and FL contexts due to the introduction of Web 2.0 applications and tools (i.e., Google Docs and wikis) and its benefits in developing learners’ writing skills.
Husam Masaoud Alwahoub, Mohd Nazri Latiff Azmi, Mohammad Halabieh   +2 more
doaj   +1 more source

Space for Two to Think: Large, High-Resolution Displays for Co-located Collaborative Sensemaking [PDF]

, 2011
Large, high-resolution displays carry the potential to enhance single display groupware collaborative sensemaking for intelligence analysis tasks by providing space for common ground to develop, but it is up to the visual analytics tools to utilize this ...
Andrews, Christopher, Bradel, Lauren, Endert, Alex, Hutchings, Duke, North, Chris, Vogt, Katherine   +5 more
core   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source

Designing Online Tools for Collaborative Knowledge Integration

Education Sciences
Collaborative discussions can significantly contribute to learners’ knowledge acquisition; however, research has shown that K-12 students will add ideas without integrating them into their existing schemas and often adopt unsubstantiated claims as their ...
Adi Kidron
doaj   +1 more source

A novel approach to collaborative product development in the medical-equipment industry [PDF]

, 2013
In this study, we summarise the requirements for collaborative product development based on our investigation of the differences in the resources and tools that are needed for the various stages of collaborative product development and the needs of ...
Chien-Lung, Hsu, Tseng, Kevin C
core  

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

A ROS2 based communication architecture for control in collaborative and intelligent automation systems [PDF]

, 2019
Collaborative robots are becoming part of intelligent automation systems in modern industry. Development and control of such systems differs from traditional automation methods and consequently leads to new challenges. Thankfully, Robot Operating System (
Bengtsson, Kristofer, Dahl, Martin, Erős, Endre, Falkman, Petter, Hanna, Atieh   +4 more
core   +3 more sources

Molecular cancer prevention: Intercepting disease

Molecular Oncology, EarlyView.
Oncological practice must evolve, from treating established tumours to proactive cancer interception before clinical manifestation. This will require mechanistic insight into tumour initiation, validated biomarkers of early disease development and redesigned clinical trials, enabling cancer interception to become a core pillar of oncology with the ...
Charlotte Grieco, Tej Pandya, Charles Swanton   +2 more
wiley   +1 more source