The use of urinary proteomics in the assessment of suitability of mouse models for ageing [PDF]
, 2017 Ageing is a complex process characterised by a systemic and progressive deterioration of biological functions. As ageing is associated with an increased prevalence of age-related chronic disorders, understanding its underlying molecular mechanisms can ...
Bajwa, Seerat +17 more
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Collagens - structure, function and biosynthesis. [PDF]
, 2003 The extracellular matrix represents a complex alloy of variable members of diverse protein families defining structural integrity and various physiological functions.
Aigner, T, Gelse, K, Poschl, E
core +1 more source
Developing Regenerative Treatments for Developmental Defects, Injuries, and Diseases Using Extracellular Matrix Collagen-Targeting Peptides. [PDF]
, 2019 Collagen is the most widespread extracellular matrix (ECM) protein in the body and is important in maintaining the functionality of organs and tissues.
Goldbloom-Helzner, Leora +2 more
core +1 more source
Hepatic stellate cells and parasite-induced liver fibrosis [PDF]
, 2010 : Fibrogenesis is a common feature of many diseases where there is severe insult to the liver. The hepatic stellate cell trans-differentiation into a myofibroblast has been identified as an important event in liver fibrogenesis and has been well ...
Allen, JT +3 more
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The role of nailfold capillaroscopy in interstitial lung diseases - Can it differentiate idiopathic cases from collagen tissue disease associated interstitial lung diseases? [PDF]
, 2015 Introduction: Nailfold capillaroscopy (NFC) is a non-invasive diagnostic test that is mostly used for early diagnosis of collagen tissue diseases (CTDs). We aimed to evaluate whether NFC findings could be a clue for discriminating idiopathic interstitial
Altınışık, Göksel +4 more
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Jornal de Pediatria, 2001 OBJETIVO: descrever um caso clínico raro na infância, com achados clínicos da síndrome do anticorpo antifosfolípide. DESCRIÇÃO: criança, sexo masculino, com 2 anos e 6 meses de idade, com insuficiência renal, trombose da artéria renal e diagnóstico de ...
Célia S. Macedo +3 more
doaj +1 more source
Dystrophic Epidermolysis Bullosa: COL7A1 Mutation Landscape in a Multi-Ethnic Cohort of 152 Extended Families with High Degree of Customary Consanguineous Marriages [PDF]
, 2017 Dystrophic epidermolysis bullosa is a heritable skin disease manifesting with sub-lamina densa blistering, erosions, and chronic ulcers. COL7A1, encoding type VII collagen, has been identified as the candidate gene for dystrophic epidermolysis bullosa. In
Abiri, Maryam +11 more
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Carotenoids - Effective Radical Scavengers for Healthy and Beautiful Skin [PDF]
, 2019 Free radicals are involved in various diseases and skin aging. To reduce and prevent this risk, our body produces antioxidants that can neutralize free radicals.
Darvin, Maxim E. +4 more
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Collagens and collagen-related diseases
Annals of Medicine, 2001 The collagen superfamily of proteins plays a dominant role in maintaining the integrity of various tissues and also has a number of other important functions. The superfamily now includes more than 20 collagen types with altogether at least 38 distinct polypeptide chains, and more than 15 additional proteins that have collagen-like domains.
J, Myllyharju, K I, Kivirikko
openaire +2 more sources
Elevated expression of type VII collagen in the skin of patients with systemic sclerosis. Regulation by transforming growth factor-beta. [PDF]
, 1994 A hallmark of systemic sclerosis (SSc) is the development of tissue fibrosis. Excessive production of several connective tissue components normally present in the dermis, including type I, III, V, and VI collagens as well as fibronectin and proteoglycans,
Christiano, Angela M. +5 more
core +3 more sources