Targeting inflammation with collagen
Clinical and Translational Medicine, 2022 Tissue damage caused by an infection or an autoimmune disease triggers degradation of collagen in the extracellular matrix (ECM), which further enhances inflammation.
Dennis Schwarz +3 more
doaj +1 more source
Glycosaminoglycans in the human cornea: age-related changes [PDF]
, 2015 AIM: To investigate possible age-related changes in glycosaminoglycans (GAGs) in the human cornea. The substances today called GAGs were previously referred to as mucopolysaccharides.
Anello, Giulia +6 more
core +2 more sources
Fibrotic and Vascular Remodelling of Colonic Wall in Patients with Active Ulcerative Colitis [PDF]
, 2016 open16noIntestinal fibrosis is a complication of inflammatory bowel disease [IBD]. Although fibrostenosis is a rare event in ulcerative colitis [UC], there is evidence that a fibrotic rearrangement of the colon occurs in the later stages.
Bassotti, Gabrio +15 more
core +2 more sources
Angiotensin type-2 (AT-2)-receptor activation reduces renal fibrosis in cyclosporine nephropathy: evidence for blood-pressure independent effect [PDF]
, 2016 Compound 21 (C21), selective agonist of AT2 receptors, shows antinflammatory effects in hypertension and nephroprotection in diabetes. The aim of this study was to evaluate the effects of C21 in cyclosporine nephropathy, which is characterized mainly by ...
Carletti, R +5 more
core +1 more source
Anemia revealing a collagenous gastritis in a young Tunisian man
The Pan African Medical Journal, 2018 Collagenous gastritis is a rare entity, characterized by the deposition of a subepithelial collagenous band with an inflammatory infiltrate in the mucosa. We report the first Tunisian case revealed by severe anemia.
Imen Akkari +4 more
doaj +1 more source
Collagen supplementation - does it bring real benefits?
Quality in Sport, 2023 Collagen is a protein and one of the main building blocks of our skin. It is found in bones, tendons, ligaments, internal organs, blood vessels, and the lining of the intestines.
Karolina Kaziród +6 more
doaj +1 more source
Early Detection and Staging of Lung Fibrosis Enabled by Collagen-Targeted MRI Protein Contrast Agent
Chemical & Biomedical Imaging, 2023 Chronic lung diseases, such as idiopathic pulmonary fibrosis (IPF) and chronic obstructive pulmonary disease (COPD), are major leading causes of death worldwide and are generally associated with poor prognoses. The heterogeneous distribution of collagen,
Oluwatosin Y. Ibhagui +24 more
doaj +1 more source
Mechanical forces regulate the interactions of fibronectin and collagen I in extracellular matrix [PDF]
, 2015 Despite the crucial role of extracellular matrix (ECM) in directing cell fate in healthy and diseased tissues--particularly in development, wound healing, tissue regeneration and cancer--the mechanisms that direct the assembly and regulate hierarchical ...
Gourdon, Delphine +7 more
core +2 more sources
Role of growth factors in the pathogenesis of tissue fibrosis in systemic sclerosis. [PDF]
, 2010 The most severe clinical and pathologic manifestations of systemic sclerosis (SSc) are the result of a fibrotic process characterized by the excessive and often progressive deposition of collagen and other connective tissue macromolecules in skin and ...
Castro, Susan V. +2 more
core +2 more sources
Detecting Collagen Molecules at Picogram Level through Electric Field-Induced Accumulation
Sensors, 2020 The demand for sensors capable of measuring low-abundant collagen in human fluids has highly increased in recent years. Indeed, collagen is expected to be a biomarker for chronic diseases and could monitor their progression.
Romina Rega +8 more
doaj +1 more source