Carotenoids - Effective Radical Scavengers for Healthy and Beautiful Skin [PDF]
, 2019 Free radicals are involved in various diseases and skin aging. To reduce and prevent this risk, our body produces antioxidants that can neutralize free radicals.
Darvin, Maxim E. +4 more
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Detecting Collagen Molecules at Picogram Level through Electric Field-Induced Accumulation
Sensors, 2020 The demand for sensors capable of measuring low-abundant collagen in human fluids has highly increased in recent years. Indeed, collagen is expected to be a biomarker for chronic diseases and could monitor their progression.
Romina Rega +8 more
doaj +1 more source
Review of the role of collagen in tumorigenesis and development
Shanghai Jiaotong Daxue xuebao. Yixue ban, 2023 Collagen is one of the most abundant proteins in the body and is the main component of the extracellular matrix. Collagen regulates cellular behavior, and its dysregulation can cause a variety of diseases, including cancer.
TANG Lei, XU Yingchun, ZHANG Fengchun
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Scientific Reports, 2021 Available therapeutics for autoimmune disorders focused on mitigating symptoms, rather than treating the cause of the disorder. A novel approach using adeno-associated virus (AAV) could restore tolerance to the autoimmune targets and provide a permanent ...
Matthew Wade +3 more
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Urine peptidomic biomarkers for diagnosis of patients with systematic lupus erythematosus [PDF]
, 2018 Background: Systematic lupus erythematosus (SLE) is characterized with various complications which can cause serious organ damage in the human body. Despite the significant improvements in disease management of SLE patients, the non-invasive diagnosis ...
Burkly, L.C. +6 more
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Lessons from helminth infections: ES-62 highlights new interventional approaches in rheumatoid arthritis [PDF]
, 2014 Parasitic worms are able to survive in their mammalian host for many years due to their ability to manipulate the immune response by secreting immunomodulatory products. It is increasingly clear that, reflecting the anti-inflammatory actions of such worm-
Al-Riyami, L. +3 more
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Matrix metalloproteinases (MMP-1, -8, -13) in chronic periapical lesions [PDF]
Vojnosanitetski Pregled, 2008 Background/Aim. Matrix metalloproteinases (MMPs) are proteolytic enzymes capable of degrading almost all extracellular matrix and basement membrane components in many destructive pathological processes, such as chronic inflammation and bone-destructive ...
Andonovska Biljana +2 more
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Endostatin in Renal and Cardiovascular Diseases
Kidney Diseases, 2021 Endostatin, a protein derived from the cleavage of collagen XVIII by the action of proteases, is an endogenous inhibitor known for its ability to inhibit proliferation and migration of endothelial cells, angiogenesis, and tumor growth.
Mei Li +4 more
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Pain pathogenesis in rheumatoid arthritis -- what have we learned from animal models [PDF]
PAIN 2018 Sep; 159 Suppl:S98-S109, 2019 Rheumatoid arthritis (RA) is a systemic autoimmune disease characterized by joint inflammation and joint pain. Much of RA treatment is focused on suppressing inflammation, with the idea being that if inflammation is controlled other symptoms, such as pain, will disappear. However, pain is the most common complaint of RA patients, is often still present
arxiv +1 more source
The role of changes in extracellular matrix of cartilage in the presence of inflammation on the pathology of osteoarthritis. [PDF]
, 2013 Osteoarthritis (OA) is a degenerative disease that affects various tissues surrounding joints such as articular cartilage, subchondral bone, synovial membrane, and ligaments.
Maldonado, Maricela, Nam, Jin
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