Results 71 to 80 of about 1,359,174 (352)

Second harmonic generation confocal microscopy of collagen type I from rat tendon cryosections [PDF]

open access: yes, 2006
We performed second harmonic generation (SHG) imaging of collagen in rat-tendon cryosections, using femtosecond laser scanning confocal microscopy, both in backscattering and transmission geometries.
Becker, DL   +3 more
core  

Performance of new gellan gum hydrogels combined with human articular chondrocytes for cartilage regeneration when subcutaneously implanted in nude mice [PDF]

open access: yes, 2009
Gellan gum is a polysaccharide that has been recently proposed by our group for cartilage tissueengineering applications. It is commonly used in the food and pharmaceutical industry and has the ability to form stable gels without the use of harsh ...
Andersson   +39 more
core   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Type II collagen scaffolds for tissue engineering

open access: yesCommunications Materials
Type II collagen (CII), a key component of cartilaginous tissues, offers an attractive option for fabricating biomimetic scaffolds that provide mechanical support and biochemical signals to facilitate cell adhesion, proliferation, and differentiation ...
Xu Hu   +4 more
doaj   +1 more source

Substrate elasticity modulates TGF beta stimulated re-differentiation of expanded human articular chondrocytes [PDF]

open access: yes, 2018
Substrate elasticity has emerged as important biomaterial design parameter. In particular, it has been reported that on soft substrates (~4kPa) freshly isolated porcine chondrocytes better maintain their phenotype than on stiffer ones (>20kPa).
Barbero, Andrea   +6 more
core  

Coinvasion of dentinal tubules by Porphyromonas gingivalis and Streptococcus gordonii depends upon binding specificity of streptococcal antigen I/II adhesin [PDF]

open access: yes, 2000
Cell wall-anchored polypeptides of the antigen I/II family are produced by many species of oral streptococci. These proteins mediate adhesion of streptococci to salivary glycoproteins and to other oral microorganisms and promote binding of cells to ...
Jenkinson, Howard F.   +3 more
core   +2 more sources

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

open access: yesMolecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak   +10 more
wiley   +1 more source

FT-IR Microspectroscopy of Rat Ear Cartilage. [PDF]

open access: yesPLoS ONE, 2016
Rat ear cartilage was studied using Fourier transform-infrared (FT-IR) microspectroscopy to expand the current knowledge which has been established for relatively more complex cartilage types.
Benedicto de Campos Vidal   +1 more
doaj   +1 more source

Increased autophagy-related 5 gene expression is associated with collagen expression in the airways of refractory asthmatics [PDF]

open access: yes, 2017
Background: Fibrosis, particularly excessive collagen deposition, presents a challenge for treating asthmatic individuals. At present, no drugs can remove or reduce excessive collagen in asthmatic airways.
Arron, Joseph R.   +10 more
core   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

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