Results 91 to 100 of about 1,359,174 (352)
Arthritogenicity of collagen type II is increased by chlorination
Summary During inflammation, activated neutrophils, monocytes and macrophages produce and release myeloperoxidase (MPO). MPO converts hydrogen peroxide to hypochlorous acid, a highly reactive and oxidizing agent. Proteins subjected to hypochlorous acid become chlorinated.
E, Westman +2 more
openaire +3 more sources
Piezoelectricity in collagen type II fibrils measured by scanning probe microscopy
The converse piezoelectric effect in collagen type II fibrils, the main collagen constituent in cartilage, was investigated using piezoresponse force microscopy.
D. Denning +5 more
semanticscholar +1 more source
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
wiley +1 more source
Responses to altered oxygen tension are distinct between human stem cells of high and low chondrogenic capacity [PDF]
Background Lowering oxygen from atmospheric level (hyperoxia) to the physiological level (physioxia) of articular cartilage promotes mesenchymal stem cell (MSC) chondrogenesis.
Brandon D. Markway +4 more
core +4 more sources
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin +3 more
wiley +1 more source
Expression of the mouse α1(II) collagen gene is not restricted to cartilage during development [PDF]
The mouse alpha 1(II) collagen gene has been isolated and a 5' portion of the gene which has low homology to other collagen genes was used to study the pattern of expression during mouse embryogenesis. In situ hybridization studies show that in the mouse,
Au, PKC, Cheah, KSE, Lau, ET, Tam, PPL
core
Characterization of the Temporomandibular Joint of Southern Sea Otters (Enhydra lutris nereis). [PDF]
The structure-function relationship of the temporomandibular joint (TMJ) of southern sea otter has largely not been described. This study aims to describe the histological, biochemical, and biomechanical features of the TMJ disk in the southern sea otter.
Arzi, Boaz +5 more
core +2 more sources
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová +2 more
wiley +1 more source
Prostaglandin E2 role in inhibition of articular cartilage collagen degradation in patients with osteoarthritis. Objective. To assess prostaglandin E2 (PGE2) role in inhibition of type II collagen digestion in explants of articular cartilage of pts with ...
E V Chetina, D DiBattista, A R Pool
doaj +1 more source
Characterization of collagen response to bone fracture healing using polarization-SHG
In this study, we extend on the three parameter analysis approach of utilizing a noninvasive dual-liquid–crystal-based polarization-resolved second harmonic generation (SHG) microscopy to facilitate the quantitative characterization of collagen types I ...
Anupama Nair +7 more
doaj +1 more source

