Epicutaneous immunization with type II collagen inhibits both onset and progression of chronic collagen-induced arthritis. [PDF]
, 2007 Epicutaneous immunization is a potential non-invasive technique for antigen-specific immune-modulation. Topical application of protein antigens to barrier-disrupted skin induces potent antigen-specific immunity with a strong Th2-bias.
Strobel, S +9 more
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Adjuvant polyarthritis. vii. The role of type ii collagen in pathogenesis [PDF]
Arthritis & Rheumatism, 1982 AbstractThe development of immune response in rats directed toward EL4 cells, after the injection of EL4 cells suspended in a saline/oil emulsion, was enhanced by the incorporation of Mycobacterium into the saline/oil emulsion; the incorporation of type II collagen into the saline–acetic acid/oil emulsion in concentrations ranging from 0.5–25 μg/ml had
Y, Iizuka, Y H, Chang
openaire +2 more sources
Topography and mechanical properties of single molecules of type I collagen using atomic force microscopy [PDF]
, 2005 Although the mechanical behavior of tendon and bone has been studied for decades, there is still relatively little understanding of the molecular basis for their specific properties.
Bozec, L. +5 more
core +1 more source
Autoimmunity against type VII collagen in inflammatory bowel disease [PDF]
Journal of Cellular and Molecular Medicine, 2009 Abstract Introduction The autoantigen: type VII collagen Autoimmunity to type VII collagen Inflammatory bowel disease Autoimmune phenomena in IBD Association of IBD with autoimmune diseases Autoimmunity to type VII collagen in IBD Autoimmunity against type VII collagen and EBA show a strong association with IBD Sequence of occurrence of skin ...
Hundorfean, Gheorghe +2 more
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Normal Molecular Weight of Type VII Collagen Produced by Recessive Dystrophic Epidermolysis Bullosa Keratinocytes [PDF]
, 1993 Studies of the recessive dystrophic form of epidermolysis bullosa (RDEB) have suggested that an abnormality in type VII collagen may be involved in the pathogenesis of this disorder.
O'Keefe, Edward +3 more
core +3 more sources
Cardiac valve disease: an unreported feature in Ehlers Danlos syndrome arthrocalasia type?
Italian Journal of Pediatrics, 2012 Ehlers Danlos syndrome (EDS) athrocalasia type (type VII), is characterized by joint hypermobility, skin hyperextensibility and tissue fragility. No heart involvement has been reported. Two forms have been described: type VII A and VII B.
Melis Daniela +6 more
doaj +1 more source
Structure and pathogenicity of antibodies specific for citrullinated collagen type II in experimental arthritis [PDF]
, 2009 Antibodies to citrulline-modifi ed proteins have a high diagnostic value in rheumatoid arthritis (RA). However, their biological role in disease development is still unclear.
Rikard Holmdahl +46 more
core +1 more source
Current approaches to the diagnosis of autoimmune bullous dermatoses
Vestnik Dermatologii i Venerologii, 2021 A modern review of highly effective methods for the diagnosis of autoimmune bullous dermatoses are presented. The specificity of the production of autoantibodies underlying bullous dermatoses are described.
Marianna B. Drozhdina +2 more
doaj +1 more source
The hinge region of type VII collagen is intrinsically disordered
Matrix Biology, 2014 Type VII collagen (Col7) is important for skin integrity. As a major component of the anchoring fibrils, Col7 is essential for linking different skin layers together. The central collagenous domain of Col7 contains several interruptions of the collagen triple helix.
Richer, Barbara Christine +1 more
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A Gene Gun-mediated Nonviral RNA trans-splicing Strategy for Col7a1 Repair
Molecular Therapy: Nucleic Acids, 2016 RNA trans-splicing represents an auspicious option for the correction of genetic mutations at RNA level. Mutations within COL7A1 causing strong reduction or absence of type VII collagen are associated with the severe skin blistering disease dystrophic ...
Patricia Peking +10 more
doaj +1 more source